Results 91 to 100 of about 345,453 (201)
Aisthesis, 2017 Through an analysis of some crucial passages from Giovanni Gentile’s Sistema di logica come teoria del conoscere, Filosofia dell’arte, Introduzione alla filosofia and Genesi e struttura della società, the paper discusses the role and significance of the ...
Roberto Diodato
doaj
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Par sentiment de cœur. Polisemia di un luogo etico-antropologico pascaliano
NoctuaThe ‘heart’, an object of misunderstanding in a sentimentalist sense, condenses in Pascal’s thought a plurality of meanings that make it, in several respects, an anthropologically pregnant and fundamental ‘place’ for the understanding of his philosophy ...
Alberto Peratoner
doaj +1 more source
Education SciencesThe purpose of this study was to measure the sense of security and comfort (SSC) as a latent construct in compulsory education. Taking theoretical considerations into account, a questionnaire for primary and secondary schools was developed in several pre-
Matthias Huber, Christoph Helm
doaj +1 more source
, 2011 In “Thinking Feeling” a camera zooms in and around an animated constellation of words. There are ten words, each repeated one hundred times. The individual words independently pulse and orbit an invisible nucleus.
Stevens, Grant William, Stevens, G
core
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Feeling our way in ecopsychology
, 2014 At a recent conference, I was asked about ecopsychology. Specifically: What kind of approach did I take to try and understand the human-nature relationship?
Stevens, Paul, Paul Stevens
core +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source