Results 121 to 130 of about 345,453 (201)
FEBS Open Bio, EarlyView.Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
FRIEDRICH SCHLEIERMACHER'E GÖRE DİN
Felsefe Dünyası, 2013 Friedrich Schleiermacher'e göre, din temelde duygusal bir olgudur. Oldukça dar anlamıyla, o, mutlak bağımlılık duygusudur. Bu duygu Tanrı ile ilişki içinde bulunma bilinci ile bir ve aynıdır.
Cenan Kuvancı
doaj
, 2010 碩士如同羅蘭巴特在對索緒爾著作的結論所言：「如果把集體的徵象視做為一種符號的體系，那就可以超越過去，很單純虔誠地揭露它。」但是我們所揭露的角度是站在什麼樣的立場？或許質疑的自問，所謂本我的立場並非如此「潔白」而是被經過交叉感染的，所以很難找到單純與虔誠的角度，只能接受神話學的說法：活在矛盾的到達極限的時代，諷刺、挖苦成為真理的代言。也許這就是人與空間對談的語言，那我的立場又是什麼？ 並不支持傳統一分為二黑白判斷觀念的我，或許對於把自身放置在一個灰色模糊地帶更能貼切現象中的真實 ...
劉康鉞; Liu, Kang-yueh
core
Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
FEBS Open Bio, EarlyView.This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
Консультативная психология и психотерапия, 2012 Article presents a model of contact in terms of phenomenology and dialogue approach. The basis of this model is described and examined with special attention to its phenomenological foundation.
Pogodin I.A.
doaj
FEBS Open Bio, EarlyView.We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia +9 more
wiley +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez +4 more
wiley +1 more source