Results 141 to 150 of about 625,964 (315)
Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
Organ donation campaigns could be more effective if they focused on feelings rather than facts [PDF]
, 2018 First paragraph: There are over 6,000 people waiting for a life-enhancing organ transplant in the UK, but there is a serious shortage of organ donors. Every day three people die waiting for a lifesaving transplant, so finding ways to increase the number ...
Miller, Jordan
core
Ciencia y Enfermería, 2007 Os objetivos desteõestudo foram identificar se as auxiliares e técnicas de enfermagem de urna unidade de internação médico-cirúrgica vivenciam sentímentos de satisfação e insatisfação no trabalho e identificar os fatores que mais contribuíram para a ...
JULIA TREVISAN MARTINS +2 more
doaj
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
WordNet-feelings: A linguistic categorisation of human feelings [PDF]
, 2018 In this article, we present the first in depth linguistic study of human feelings. While there has been substantial research on incorporating some affective categories into linguistic analysis (e.g.
Lowe, Leroy +5 more
core +1 more source
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Harm, Feelings, and Wrongness [PDF]
, 2011 While feelings and emotions are quite important in daily life, their role in morality has often been underplayed. Although there have been some ethical theories, such as David Hume's sentimentalism, that place feelings as an important cornerstone of ...
Lind, Michael
core +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source