Results 131 to 140 of about 625,964 (315)
Drawing on methods and theories from the history of emotions, this paper examines the Twin Stelae that flank the entrance into Ramses II’s Great Temple at Abu Simbel in order to investigate the feelings associated with ancient Egyptian kingship from an ...
Tara Prakash
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Latent variable modelling of the relationship between flow and exercise-induced feelings: an intuitive appraisal perspective [PDF]
[Abstract]: The present study examined the relationship between self-reported levels of Flow (Csikszentmihalyi, 1975) and the post-exercise feelings of Positive Engagement, Revitalisation, Tranquillity, and Physical Exhaustion (Gauvin & Rejeski, 1993 ...
Terry, Peter C. +2 more
core
Feeling Poor, Feeling Rich, or Feeling Middle-Class
Based on their objective economic situation and comparing with their peers, individuals form perceptions of their economic position in a society. Data from the three waves of the Life in Transition surveys of European countries show that these perceptions systematically deviate from the rankings obtained using consumption levels.
Lebrand, Mathilde +3 more
openaire +1 more source
Astrocyte heterogeneity in brain metastases
Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver +2 more
wiley +1 more source
Emotions, Feelings, and Personhood [PDF]
The paper argues that an analysis of the language of feelings and emotions display the recognition by most that they are two distinct, though related, ideas.
Kira, Joshua, Gilhooly, John R.
core
Editorial: How do Emotions and Feelings Regulate Physical Activity?
Darko Jekauc, Ralf Brand
doaj +1 more source
From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard +8 more
wiley +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source

