Results 131 to 140 of about 2,258,876 (361)
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Emotional intelligence: on the problem of defining the concept
Вестник университетаThe article is devoted to substantiate the need to clarify the definition of emotional intelligence (hereinafter referred to as EI). With consideration to the accumulated data on the neurophysiological foundations of EI and psychological trauma, as well ...
E. N. Rastorgueva
doaj +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
SpekiThis special issue, Feeling Forward: Contemporary Nordic perspectives on emotion, affect and feeling in philosophy of education, brings together contributions that examine the role of emotion, feeling and affect in educational theory and practice from ...
Claudia Schumann , Marie Hållander
doaj +1 more source
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
Feature Review of Matthew Bannister (1999) Positively George Street: A personal history of Sneaky Feelings and the Dunedin Sound, Auckland: Reed [PDF]
, 2001 Feature review of the book: Matthew Bannister (1999) Positively George Street: A personal history of Sneaky Feelings and the Dunedin Sound, Auckland ...
McCleay, Colin
core +1 more source
The Feel of Life: Resonance, Race, and Representation
International Journal of Communication, 2015 This article uses examples of the viral circulation of the images of Black people in the new media ecology of television news and YouTube to suggest that the feelings these images evoke exceed the legibility of their semiotic meaning and the promise of ...
Herman Gray
doaj
ArtsDrawing on methods and theories from the history of emotions, this paper examines the Twin Stelae that flank the entrance into Ramses II’s Great Temple at Abu Simbel in order to investigate the feelings associated with ancient Egyptian kingship from an ...
Tara Prakash
doaj +1 more source