Results 61 to 70 of about 11,973,388 (377)

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

Molecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim, Myunghee Kang, Soyeon Jeong, Jisup Kim, Kyoung Oh Kim, Won‐Suk Lee, Jeong‐Heum Baek, Jung Ho Kim, Seungyoon Nam   +8 more
wiley   +1 more source

Interaction of sperm with endometrium can regulate genes involved in endometrial receptivity pathway in mice: An experimental study

International Journal of Reproductive BioMedicine, 2020
Background: Many researchers consider implantation and endometrial receptivity as pertinent issues in reproductive science. Although, several experiments have been performed and their results evaluated, yet there is no confirmed evidence about the ...
Marziyeh Ajdary, Zahra Zandieh, Fatemeh Sadat Amjadi, Fariborz Keyhanfar, Mehdi Mehdizadeh, Reza Aflatoonian   +5 more
doaj   +1 more source

A novel and compact review on the role of oxidative stress in female reproduction

Reproductive Biology and Endocrinology, 2018
In recent years, the study of oxidative stress (OS) has become increasingly popular. In particular, the role of OS on female fertility is very important and has been focused on closely.
Jiayin Lu, Zixu Wang, Jing Cao, Yaoxing Chen, Yulan Dong   +4 more
semanticscholar   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

Holoprosencephaly: A Case Report and Review of Prenatal Sonographic Findings [PDF]

International Journal of Fertility and Sterility, 2008
Holoprosencephaly is a rare intracranial abnormality. The incidence of holoprsencephaly is between 0.56-0.63 of 10,000 live-born infants10. It has classified into three degrees, alobar, semilobar and lobar.
Maryam Niknejadi, Firoozeh Ahmadi, Shohreh Irani   +2 more
doaj   +1 more source

Divided Consciousness And Female Companionship: Reconstructing Female Subjectivity On Greek Vases [PDF]

, 1997
Art ...
Petersen, Lauren H.
core   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

Exposure to high dose of polystyrene nanoplastics causes trophoblast cell apoptosis and induces miscarriage

Particle and Fibre Toxicology
Background With rapid increase in the global use of various plastics, microplastics (MPs) and nanoplastics (NPs) pollution and their adverse health effects have attracted global attention.
Shukun Wan, Xiaoqing Wang, Weina Chen, Manli Wang, Jingsong Zhao, Zhongyan Xu, Rong Wang, Chenyang Mi, Zhaodian Zheng, Huidong Zhang   +9 more
doaj   +1 more source

Cardiovascular Disease and the Female Disadvantage

International Journal of Environmental Research and Public Health, 2019
Age-standardised rates of cardiovascular disease (CVD) are substantially higher in men than women. This explains why CVD has traditionally been seen as a “man’s problem”.
M. Woodward
semanticscholar   +1 more source

Female Gamers: [PDF]

, 2013
International evidence indicates that the number of females involved in video-gaming is increasing. Within the context of this increase, there is a need to explore the experiences of this group of gamers in detail.
A.Lewis, C. L.Muehlenhard, D. A.Gentile, D.Ghuman, M. D.Giffiths, M. D.Griffiths, R. T. A.Wood   +6 more
core   +1 more source