Results 61 to 70 of about 8,726,539 (311)
Molecular Oncology, EarlyView.This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke +12 more
wiley +1 more source
Cardiovascular DiabetologyObjective To evaluate the efficacy of anti-CD3 monoclonal antibody (mAb) in patients with type 1 diabetes (T1D) and identify the influencing factors.
Qi Wu +5 more
doaj +1 more source
Sexual Medicine, 2016 Introduction: Female sexual dysfunction affects up to 43% of women in the United States and hypoactive sexual desire disorder (HSDD) is the most common type; however, we lack treatment options showing improvement for this condition.
Susan H. Oakley, MD, FACOG +3 more
doaj +1 more source
Successful Treatment of Obstructive Oligospermia/Azoospermia Due to Mullerian Duct Cyst by Transurethral Resection: A Case Report [PDF]
International Journal of Fertility and Sterility, 2007 Cystic lesions in midline of prostate are uncommon and considered as congenital disorders. Here we report a 33- year- old male who presented with either azoospermia or decreased ejaculate volume leading to infertility and for whom performing Transrectal ...
Ahmad Vosough +4 more
doaj +1 more source
Simulation of reproductive risk and emergence of female reproductive cessation [PDF]
, 2002 Using a simple computer model for evolution, we show that in a sexual population subject only to age-increasing reproductive risk, a cessation of female reproduction emerges.
arxiv +1 more source
Genomic landscape and preclinical models of angiosarcoma
Molecular Oncology, Volume 19, Issue 4, Page 965-983, April 2025.Angiosarcomas are a rare and aggressive cancer with a poor prognosis for patients. The genomic landscape of angiosarcoma can be highly complex and heterogenous; however, recent studies have identified some common features especially within anatomic and molecular subgroups.
Annaleigh Benton +3 more
wiley +1 more source
Breast density in polycystic ovarian syndrome patients: A case-control study
International Journal of Reproductive BioMedicine, 2019 Background Epidemiological studies suggested a positive relationship between breast density and risk of breast cancer. One of the common hormonal disorders in women's reproductive age is polycystic ovarian syndrome (PCOS) and the results from the ...
Bita Eslami +4 more
doaj +1 more source
Molecular Oncology, Volume 19, Issue 5, Page 1386-1403, May 2025.Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale +9 more
wiley +1 more source
Advanced ScienceHuman trophoblast cells are crucial for healthy pregnancy. However, whether the defective homologous recombination (HR) repair of dsDNA break (DSB) in trophoblast cells may induce miscarriage is completely unknown.
Weina Chen +11 more
doaj +1 more source
Molecular Oncology, EarlyView.The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu +3 more
wiley +1 more source