Results 91 to 100 of about 1,407,592 (395)

Beware of bone pain with bisphosphonates [PDF]

, 2019
A 71-year-old woman who had been taking ibandronate for 10 years presented to an Endocrinology Department with persistent mid-thigh pain. Pelvic X-ray showed bilateral femoral cortical expansion, indicating impending atypical femoral fractures (AFFs ...
Fraser, William, Mailoo, Venthan Jeyarantan, Srinivas, Vidya, Turner, Jeremy   +3 more
core   +1 more source

Association of atypical femoral fractures with bisphosphonate use by patients with varus hip geometry.

Journal of Bone and Joint Surgery. American volume, 2014
BACKGROUND There is increasing evidence associating "atypical" femoral fractures with prolonged exposure to bisphosphonate therapy. The cause of these fractures is unknown and likely multifactorial.
J. Hagen, A. Miller, S. Ott, M. Gardner, Saam Morshed, K. Jeray, Timothy B. Alton, Dennis Ren, W. P. Abblitt, J. Krieg   +9 more
semanticscholar   +1 more source

Ultrasound‐Responsive Piezoelectric Membrane Promotes Osteoporotic Bone Regeneration via the “Two‐Way Regulation” Bone Homeostasis Strategy

Advanced Science, EarlyView.
Patients with osteoporosis face a higher risk of bone injury, mainly due to weakened osteogenic differentiation and bone formation, along with increased osteoclast differentiation and bone resorption activity, leading to bone homeostasis imbalance.
Xinhui Wu, Tianlong Wang, Jinhui Zhao, Lei Zhang, Zhiqing Liu, Yixing Chen, Yiping Luo, Yaqi Liu, Yan Chen, Hui Jiang, Dilixiati Duolikun, Junjian Liu, Wentao Cao, Longpo Zheng   +13 more
wiley   +1 more source

Growth Plate Injuries of the Lower Extremity: Case Examples and Lessons Learned. [PDF]

, 2018
BackgroundThe presence of growth plates at the ends of long bones makes fracture management in children unique in terms of the potential risk of developing angular deformities and growth arrest.Materials and methodsWe discuss three distinct cases ...
Sabharwal, Samir, Sabharwal, Sanjeev
core   +3 more sources

Targeting Hyperglycemic Bone Pre‐Metastatic Niche for Breast Cancer Bone Metastasis Therapy

Advanced Science, EarlyView.
This study reveals that breast cancer creates a hyperglycemic pre‐metastatic niche in bone prior to colonization and amplifies glucose metabolism post‐metastasis. To target this mechanism, a biomimetic enzyme‐engineered nanoplatform that disrupts tumor glycolytic pathways, proposing a therapeutic strategy to inhibit breast cancer bone metastasis by ...
Jianxin Ye, Peng Hu, Rui Zhang, Lei Zhou, Zonghua Luo, Yanan Chen, Shengzhe Ruan, Mengyi Zhu, Huaze Ding, Yike Qian, Yan Xing, Tong Meng, Changping Wang, Dianwen Song   +13 more
wiley   +1 more source

Age relationship with incidence of proximal femur fracture at PKU Muhammadiyah Yogyakarta Hospital in 2022 [PDF]

BIO Web of Conferences
Femoral fracture is a condition where there is a disturbance in the discontinuity of the femur bone which can be caused by accidents, degenerative and pathological processes.
Arrozhi Muhammad Yusuf, Hikmawan Taufiek, Sambada Benni, Silvia Ipho, Latif Anwarudin, Wijaya Adi Indra, Kadarmo Dhiwangkoro Aji   +6 more
doaj   +1 more source

Dual-mobility socket in challenging total hip arthroplasty : 2-6 years follow-up. [PDF]

, 2018
The success of dual-mobility sockets in achieving implant stability in primary hip replacement is already well established. However, stability cannot always be achieved, especially when dealing with more difficult indications.
Audenaert, Emmanuel, Pattyn, Christophe, Willekens, Philippe   +2 more
core   +1 more source

Biomechanical properties of bone in a mouse model of Rett syndrome [PDF]

, 2015
Rett syndrome (RTT) is an X-linked genetic disorder and a major cause of intellectual disability in girls. Mutations in the methyl-CpG binding protein 2 (<i>MECP2</i>) gene are the primary cause of the disorder.
Cobb, Stuart R, Constante, Diogo, Isaksson, Hanna,, Kamal, Bushra, Lund University., Mathavan, Neashan,, Payne, Anthony, Russell, David, Tanner, Elizabeth   +8 more
core   +1 more source

A Study of Skeletal Stem Cell Dynamics and Its Potential Applications in the Design of a Titanium Implant for Senile Osteoporosis

Advanced Science, EarlyView.
Senescent mesenchymal stromal cells (MSCs) drive age‐related osteoporosis (A‐OP) via adipogenic bias. Resveratrol, selected from transcriptome‐identified core genes, is delivered locally using GelMA‐chitosan hydrogel‐functionalised titanium implants. In A‐OP microenvironments, the hydrogel enables the sustained release of resveratrol, which reverses ...
Wuzhe Fan, Tao Zheng, Mingsong Mao, Pengfei Gao, Yulu Yang, Rong Wang, Yao Yang, Yangpeng Zuo, Tiantian Yuan, Ruqing Bai, Weihu Yang, Xingchen Yan, Kaiyong Cai   +12 more
wiley   +1 more source

Alendronate or alfacalcidol in glucocorticoid-induced osteoporosis [PDF]

, 2006
BACKGROUND: Treatment with glucocorticoids is associated with bone loss starting soon after therapy is initiated and an increased risk of fracture. METHODS: We performed a randomized, double-placebo, double-blind clinical trial of 18 months' duration ...
Ale Algra, Anne-Margriet Huisman, Ans C.M. Oostveen, Ben A.C. Dijkmans, Chris E.D. de Laet, de Nijs RN, Erik Buskens, George A.W. Bruyn, Johannes W.G. Jacobs, Johannes W.J. Bijlsma, Michel BA, Piet P.M.M. Geusens, Roland F.J. Laan, Ron N.J. de Nijs, Willem F. Lems   +14 more
core   +4 more sources