Results 81 to 90 of about 412,843 (303)

Locking plates for distal femur fractures does an increased working length improve healing? [PDF]

open access: yes, 2013
Includes abstract.Includes bibliographical references.Distal femur locking plates have become a very popular means of internal fixation because of their ability to provide stable distal periarticular fixation.
Koller, Ian M
core   +1 more source

Femoral Neck Fracture With Anterior Tilt

open access: yesOrthopaedic Surgery
Objective Posteriorly tilted femoral neck fractures have been extensively studied, whereas anteriorly tilted fractures remain largely unreported. This study aims to characterize the clinical features, radiographic patterns, and postoperative outcomes of ...
Yu‐Kai Wang   +7 more
doaj   +1 more source

Dynamic Hip Screw and Compression Plate Fixation of Ipsilateral Femoral Neck and Shaft Fractures

open access: yesJournal of Orthopaedic Surgery, 2008
Purpose. To evaluate surgical outcomes of ipsilateral femoral neck and shaft fractures. Methods. Between April 1997 and September 2004, 29 men and 8 women (mean age, 37 years) underwent fixation of femoral neck and shaft fractures using a dynamic ...
A Abalo   +5 more
doaj   +1 more source

Matrix Stiffness Orchestrates Mesenchymal Stem Cell Lineage Commitment Toward Osteogenesis and Adipogenesis Through the PIEZO1/SP1/STC2 Axis

open access: yesAdvanced Science, EarlyView.
Matrix stiffness directs mesenchymal stem cell lineage commitment through PIEZO1‐dependent activation of the SP1/STC2 pathway. Stiff matrices favor osteogenesis and suppress adipogenesis, whereas the loss of PIEZO1 function impairs early bone formation. STC2 retains lineage‐regulatory activity even when PIEZO1 is inactive.
Shuo Zhang   +12 more
wiley   +1 more source

Femoral Neck Shaft Angle in Men with Fragility Fractures

open access: yesJournal of Osteoporosis, 2011
Introduction. Femoral neck shaft angle (NSA) has been reported to be an independent predictor of hip fracture risk in men. We aimed to assess the role of NSA in UK men. Methods. The NSA was measured manually from the DXA scan printout in men with hip (62,
S. P. Tuck   +6 more
doaj   +1 more source

Gut Microbiota‐Derived Indole‐3‐Propionic Acid Alleviates Diabetic Osteoporosis Through Nrf2‐Mediated Ferroptosis Suppression

open access: yesAdvanced Science, EarlyView.
Diabetes‐associated dysbiosis is accompanied by reduced Clostridium abundance, impaired microbial tryptophan metabolism, and lower circulating indole‐3‐propionic acid (IPA). Exogenous IPA improves trabecular microarchitecture and bone formation and restores Nrf2‐associated antioxidant signaling in bone marrow mesenchymal stem cells, limiting iron ...
Jinwu Bai   +12 more
wiley   +1 more source

TNAP and PHOSPHO1 Function Synergistically to Afford Critical Control Over the Mineralization of the Postnatal Murine Skeleton

open access: yesAdvanced Science, EarlyView.
Biomineralization underpins skeletal development, yet its molecular control remains incompletely understood. Using a novel murine knockout model, this study reveals the essential and complementary roles of PHOSPHO1 and TNAP in postnatal skeletal development.
Lucie E. Bourne   +15 more
wiley   +1 more source

Bisphosphonate-induced femoral fragility fractures: What do we know?

open access: yes, 2010
Arkan S Sayed-Noor1,2, Bakir K Kadum1, Göran O Sjödén1,21Department of Orthopaedic Surgery, Sundsvall Hospital, Sundsvall, Sweden; 2Department of Surgical and Perioperative Sciences, Norrlands University Hospital, Ume& ...
Göran O Sjödén   +2 more
core  

Puerarin‑Loaded pH‑Responsive ZIF‑90 Nanoparticles Ameliorate Osteoporosis via Enhancing H3K18 Lactylation and Suppressing Aberrant Osteoclast Activation

open access: yesAdvanced Science, EarlyView.
Schematic illustration of the mechanism by which ZIF‐90@PU alleviates osteoporosis via H3K18la‐mediated NFATc1 pathway suppression. ABSTRACT Osteoporosis is characterized by dysregulated osteoclast activity, leading to excessive bone resorption and structural damage.
Jiajia Lu   +5 more
wiley   +1 more source

Encouraging Results of Treating Femoral Trochanteric Fractures with Specially Designed Double-Screw Nails

open access: yes, 2008
Background: Conventional intramedullary nails for trochanteric fractures have the disadvantages of intraoperative splintering resulting from large proximal section and postoperative femoral fracture caused by stress concentration at the nail tip.
LIN, JINN, 林晉
core  

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