Results 61 to 70 of about 86,807 (268)

Targeting Endogenous Lipophagy: A Novel Strategy to Enhance MSC Osteogenesis and Mineralization for Senile Osteoporosis Therapy

Advanced Science, EarlyView.
Schematic representation of the role of lipophagy in bone mesenchymal stem cells(MSCs). In healthy MSCs, functional lipophagy efficiently degrades lipid droplets to support oxidative phosphorylation and cellular energy production, thereby facilitating osteogenic differentiation and matrix mineralization.
Chaoqiang Chen, Zhidong Liu, Yanhang Sun, Xiaojun Xu, Zhexiao Lan, Junhao Zhao, Peitao Xu, Guiwen Ye, Jinteng Li   +8 more
wiley   +1 more source

Performance of the resurfaced hip. Part 1: the influence of the prosthesis size and positioning on the remodelling and fracture of the femoral neck

, 2010
Hip resurfacing is an established treatment for osteoarthritis in young active patients. Failure modes include femoral neck fracture and prosthesis loosening, which may be associated with medium-term bone adaptation, including femoral neck narrowing and ...
Taylor, Andrew C., Browne, Martin, Dickinson, Alexander   +2 more
core   +1 more source

A Piezo‐Mimetic Ionic Hydrogel Harnessing Joint Motion for Cartilage Repair

Advanced Science, EarlyView.
A piezo‐mimetic ionic hydrogel converts mechanical deformation into bioactive ionic currents via stress‐induced asymmetric ion migration. Coupled with sustained Mg2+ release, this mechano‐electrochemical platform bridges mechanical loading and cellular signaling, enabling load‐adaptive stimulation and enhanced cartilage regeneration. ABSTRACT Articular
Chenyuan Gao, Xinyu Wang, Zhifeng Wu, Xinya Zhang, Xiao Geng, Ti Zhang, Yue Wang, Hongwei Xia, Jun Zhang, Xianbo Qiu, Cuiru Sun, Yingjie Yu, Wenli Dai, Hua Tian, Qing Cai   +14 more
wiley   +1 more source

Influence of associated femoral head fractures on surgical outcomes following osteosynthesis in posterior wall acetabular fractures

BMC Musculoskeletal Disorders, 2022
Background To date, no study has compared the surgical outcomes between posterior wall acetabular fractures with and without associated femoral head fractures. Therefore, we evaluated whether an associated femoral head fracture increases the incidence of
Po-Ju Lai, Chih-Yang Lai, I-Chuan Tseng, Chun-Yi Su, Yi-Hsun Yu   +4 more
doaj   +1 more source

Orchestrated Engineered Polyphenol‐Peptide Condensates Coupled With β‐GP Reverses Diabetic Osteoporosis by Remodeling Mitophagy

Advanced Science, EarlyView.
A multifunctional β‐GP@EGCG‐E7 nanoplatform is engineered by polyphenol–peptide condensation and phosphate loading. Bone‐targeted delivery, antioxidant and anti‐inflammatory activity, and mitophagy restoration are integrated in one system, enabling protection of osteoblasts and endothelial cells and promoting bone regeneration under diabetic ...
Xiuyun Xu, Meiqin Zhang, Ting Wu, Erfan Wei, Andrei Y. Hancharou, Zeying Wang, Zijuan Wang, Letian Lv, Likun Wu, Xingtong Pan, Qiyue Zhu, Xinyi Dong, Hao Liu, Yongsheng Zhou   +13 more
wiley   +1 more source

Prevalent morphometric vertebral fractures in professional male rugby players.

, 2014
There is an ongoing concern about the risk of injury to the spine in professional rugby players. The objective of this study was to investigate the prevalence of vertebral fracture using vertebral fracture assessment (VFA) dual energy X-ray ...
Beck, B., Hind, K., Birrell, F., Birrell, Fraser, Birrell Fraser, Hind, K, Belinda Beck, Beck, Belinda, Fraser Birrell, Hind Karen, Hind, Karen, Beck Belinda, Karen Hind, Beck, B, Birrell, F   +14 more
core   +1 more source

Biodegradable Zn‐Based Implants: Progress, Challenges, and Pathways toward Clinical Translation

Advanced Science, EarlyView.
Exploring biodegradable Zn‐based implants offers a promising pathway to next‐generation biomedical devices with balanced degradation and biocompatibility. A comprehensive overview of biodegradable Zn‐based implants, covering their biological significance, material design principles, and advanced engineering strategies is provided.
Panfeng Zhao, Zhengquan Wang, Hui Yang, Xiyuan Zhang, Hanyuan Liu, Xiaotong Lu, Xiaocheng Li, Yanyan Liu, Xi Zhao, Wenhao Zhou, Yufeng Zheng   +10 more
wiley   +1 more source

Failure after operative repair is higher for ballistic femoral neck fractures than for closed, blunt-injury fractures: a multicenter retrospective cohort study

Trauma Surgery & Acute Care Open
Introduction The purpose of this study was to describe the outcomes after operative repair of ballistic femoral neck fractures. To better highlight the devastating nature of these injuries, we compared a cohort of ballistic femoral neck fractures to a ...
Ranjan Gupta, Henry Tout Shu, Diane Ghanem, Davis L. Rogers, Oscar Covarrubias, Paul Izard, Jacques Hacquebord, Philip Lim, Greg M. Osgood, Babar Shafiq   +9 more
doaj   +1 more source

Dynamic Hip Screw and Compression Plate Fixation of Ipsilateral Femoral Neck and Shaft Fractures

Journal of Orthopaedic Surgery, 2008
Purpose. To evaluate surgical outcomes of ipsilateral femoral neck and shaft fractures. Methods. Between April 1997 and September 2004, 29 men and 8 women (mean age, 37 years) underwent fixation of femoral neck and shaft fractures using a dynamic ...
A Abalo, A Dossim, AF Ouro Bangna, K Tomta, A Assiobo, A Walla   +5 more
doaj   +1 more source

Femoral insufficiency fractures in the elderly – Excessive medial femoral bowing complicates intramedullary nailing

Acta Orthopaedica et Traumatologica Turcica, 2020
Objective: The aim of this study was to evaluate the characteristics of low-energy femoral insufficiency fractures in elderly patients. Methods: The study retrospectively evaluated the clinical course of 4 patients with low-energy femoral shaft and ...
Mehmet Hakan Ozsoy, Mehmet Atıf Erol Aksekili, Onur Kizilay, Veysel Ercan Dincel, Nevres Hurriyet Aydogan, Arzu Ozsoy   +5 more
doaj   +1 more source