Results 91 to 100 of about 412,843 (303)

The design, manufacture and analysis of a new implant for fracture fixation in human and veterinary orthopaedic surgery: the bone fastenerod [PDF]

, 2002
Fracture fixation in humans and animals has troubled surgeons and scientists since first it was attempted right up to the present day. At every milestone of achievement in the understanding and practice of fracture repair there has remained a significant
McCartney, William T.
core   +2 more sources

Comparison of Atypical and Osteoporotic Femoral Shaft Fractures in the Elderly: A Multicenter Study

Advances in Orthopedics, 2018
Background. In atypical femoral fractures, owing to the high rates of complications and delayed healing that accompany the plate fixation, the most favorable treatment is intramedullary nailing.
Takanori Miura, Hiroaki Kijima, Noriyuki Ishikawa, Toshihito Ebina, Takayuki Tani, Shuichi Chida, Tetsuya Suzuki, Satoshi Yumto, Hiroshi Tazawa, Naohisa Miyakoshi, Yoichi Shimada   +10 more
doaj   +1 more source

Transfer RNA‐Derived Small RNA‐5’tiRNAGln Drives HNRNPC Phase Separation to Promote Breast Cancer Bone Metastasis by Regulating IGF1R

Advanced Science, EarlyView.
This study reveals that 5'tiRNA‐Gln interacts with hnRNPC to promote IGF1R liquid‐liquid phase separation, which drives ERK1/2 signaling activation, EMT, and breast cancer bone metastasis. These findings highlight a novel mechanism of breast cancer bone metastasis and potential therapeutic target in metastatic breast cancer.
Bingnan Wang, Dongsong Liu, Xiaozhi Fan, Jiale Fan, Xuesi liu, Yu Wang, Zixin Wang, Mo Cheng, Ping Zhou, Wangjun Yan   +9 more
wiley   +1 more source

A Neutrophil Membrane‐Encapsulated Pd/hCeO2 Nanoformulation for Alleviating Age‐Dependent Perioperative Neurocognitive Disorders

Advanced Science, EarlyView.
This study reports a neutrophil membrane‐encapsulated Pd/hCeO2 nanozyme (PCN) for targeted treatment of perioperative neurocognitive disorders (PND) in aged mice. PCN inhibits glycolysis‐driven microglial activation and neuroinflammation, improves mitochondrial respiration, and maintains blood‐brain barrier integrity and synaptic function, ultimately ...
Lili Huang, Jiahui Cheng, Huan Xu, Qiang Zhang, Xiao Zhang, Ye Liu, Yizhe Zhang, Wanbing Dai, Zhi Xiong, Linghuan Guo, Lingling Xu, Wen Wang, Xin Xu, Yan Zhou, Weifeng Yu, Bo Li, Diansan Su, Daxiang Wen   +17 more
wiley   +1 more source

Changes in the anatomical position of the superficial and deep femoral arteries during internal fixation of intertrochanteric fractures

, 2022
Introduction Fixation for intertrochanteric proximal femoral fractures are increasing globally, one of the risks with surgical treatment is injury to the deep and superficial femoral arteries (DFA and SFA, respectively).
Coughlan, A, Nusem, I, Ng, SK
core   +1 more source

The prevalence of fracture extension in displaced femoral neck fractures in the elderly

OTA International, 2019
. Objective:. Arthroplasty is the common treatment for intracapsular femoral neck fractures in the elderly. Recent studies have shown that there may be more overall complications related to uncemented hemiarthroplasty compared to cemented, including more
Kyle Matsuo Natsuhara, MD, Robert Downey Boutin, MD, Mark Andrew Lee, MD, John Patrick Meehan, MD   +3 more
doaj   +1 more source

Severe ADEM‐Like Neuroinflammatory Disease and Cerebrovascular Fragility With Recurrent Pseudoaneurysms and Moyamoya in a Familial Germline CBL Mutation: Expanding the Clinical Phenotype

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Heterozygous germline variants in CBL disrupt its function as a negative regulator of the Ras/MAPK pathway, classically predisposing to Juvenile myelomonocytic leukemia (JMML) and moyamoya. We describe two affected siblings carrying a paternally inherited CBL variant (c.1210 T> C, p.
Michal Bar‐Hakim, Anat Abramovich, Sara Via‐Dorembus, Gali Heimer, Bruria Ben‐Zeev, Etai Adam, Assaf A. Barg, Jonathan Roth, Basheer Sheick‐Yousif, Rony Beeri Berkowiz, Michal Feldon, Haim Bassan, Moran Hausman‐Kedem   +12 more
wiley   +1 more source

Global Trends in the Incidence and Primary Causes of Femoral Fractures, Excluding Femoral Neck Fractures: A Global Epidemiological Study [PDF]

Fanyu Fu,1,* Bo Liu,2,* Haifang Pu,3 Yuebin Wang,3 Pengfei Zhang,1 Song Wei,1 Hao Gu,1 Qian Zhang,4 Hengli Ye5 1College of Physical Education and Health Science, Yibin University, Yibin, 644000, People’s Republic of China; 2Department of ...
Fu F, Gu H, Wei S, Liu B, Pu H, Wang Y, Ye H, Zhang Q, Zhang P   +8 more
core  

Antibiofilm-coated intramedullary nailing for tibial and femoral diaphyseal fractures at high-risk infection: outcomes of 103 consecutive patients

Journal of Orthopaedics and Traumatology
Background Fracture-related infection (FRI) is a devastating complication of intramedullary nailing of tibial and femoral diaphyseal fractures. The present study evaluates the clinical efficacy of an antibacterially coated intramedullary nail in patients
Giovanni Vicenti, Filippo Migliorini, Michele Loiodice, Alessandro Scarpino, Priscilla D’attis, Luise Schäfer, Giulia Colasuonno, Giuseppe Solarino   +7 more
doaj   +1 more source

Severe Phenotype in an Indian Family With Progressive Pseudorheumatoid Arthropathy of Childhood

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Progressive pseudorheumatoid arthropathy of childhood (PPAC) is a rare autosomal recessive progressive condition that affects the cartilage of joints and bones. The symptoms of PPAC include stiffness of the joints, bony swelling of the toes and fingers, short stature, kyphosis, and muscle weakness.
Narinder Singh, Arpita Neogi, Liliane H. Gibbs, Jagdish Soni, Elizabeth Chao, Virginia Kimonis   +5 more
wiley   +1 more source