Results 101 to 110 of about 1,407,592 (395)

Denosumab and atypical femoral fractures

Acta Orthopaedica, 2014
Stress fractures of the femoral shaft or subtrochanteric region (atypical femoral fractures) are clearly associated with bisphosphonate use. This association is stronger than the one between smoking and lung cancer.
P. Aspenberg
semanticscholar   +1 more source

A Phase 3 Multicenter, Double‐Blind Study Comparing Efficacy, Safety, Immunogenicity, and Pharmacokinetics of Alkem's Biosimilar Teriparatide Versus Reference Teriparatide in Postmenopausal Osteoporosis

AGING MEDICINE, Volume 8, Issue 3, Page 267-274, June 2025.
This phase III study demonstrated that Alkem's biosimilar teriparatide is noninferior to reference teriparatide in improving bone mineral density at the lumbar spine and femoral neck in postmenopausal osteoporosis patients, with comparable safety, pharmacodynamics, and immunogenicity profiles over 48 weeks of treatment.
Nitin Kapoor, Thomas Paul, Rajeshwar Nath Srivastava, Saurabh Singh, Sunil Maheshwari, Vishal Patil, Awadhesh Kumar Yadav, Girish Bhatia, Sushil H. Mankar, Joe Joseph Cherian, Surabhi Maheshwari, Sudeepti Srivastava, Dattatray Pawar, Roshan Pawar, Amol Aiwale, Amitrajit Pal, Yogesh Rane, Vinayaka Shahavi, Akhilesh Sharma   +18 more
wiley   +1 more source

Influence of the arterial elastic component on the response to balloon angioplasty in femoral arteries of a healthy porcine model

Animal Models and Experimental Medicine, EarlyView.
This study evaluates the role of elastin in vascular response 28 days after balloon angioplasty using uncoated and paclitaxel‐coated balloons in a healthy porcine model. The results show higher elastin content in external femoral arteries, which is inversely correlated with vascular injury, inflammation, smooth muscle cell loss, proteoglycan and fibrin
María Gracia de Garnica García, Marina Gil Bernabé, Claudia Pérez‐Martínez, Laura Mola Solà, Luis Duocastella Codina, María Molina Crisol, Alex Gómez Castel, Armando Pérez de Prado   +7 more
wiley   +1 more source

A secondary atypical diaphyseal femoral fracture after intramedullary nailing for an atypical subtrochanteric femoral fracture: A case report

Trauma Case Reports
Intramedullary nailing is the gold standard of treatment for atypical femoral fractures, with a few reports of secondary atypical subtrochanteric femoral fractures following intramedullary nailing for atypical diaphyseal femoral fractures. However, there
Shuya Nohmi, Masakazu Kogawa, Taro Ogawa
doaj  

Hoffa fracture associated with ipsilateral femoral shaft fracture: clinical feature and treatment

Chinese Journal of Traumatology, 2012
【Abstract】Hoffa fracture associated with ipsilateral femoral shaft fracture is very rare. Three cases of this rare type of injury were retrospectively reviewed. The sites of femoral shaft fractures and Hoffa fractures were documented.
GONG Yu-bao, LI Qing-song, YANG Chen, LI Shu-qiang, LIU Jian-guo, QI Xin   +5 more
doaj  

Vascular injuries due to cerclage passer: Relevant anatomy and note of caution

Journal of Orthopaedic Surgery, 2018
Purpose: The cerclage passer instrument was introduced for aiding percutaneous reduction in spiral femur fractures, thereby overcoming the risk of devascularization of the fracture ends commonly associated with traditional open cerclage wiring techniques.
Agraharam Devendra, M Avinash, Dinesh Chidambaram, Jayaramaraju Dheenadhayalan, S Rajasekaran   +4 more
doaj   +1 more source

Hoffa Fracture of the Femoral Condyle

Radiology Case Reports, 2008
In this report, we present a case of an uncommon coronal fracture of the femoral condyle, known as a Hoffa fracture. Classification of these injuries and commonly associated injuries are discussed. We describe previously proposed mechanisms of injury and review the current literature.
Eva M. Escobedo, John K. Hunter, Walter Mak   +2 more
openaire   +3 more sources

Histology of 8 atypical femoral fractures

Acta Orthopaedica, 2014
Background and purpose — The pathophysiology behind bisphosphonate-associated atypical femoral fractures remains unclear. Histological findings at the fracture site itself may provide clues. Patients and methods — Between 2008 and 2013, we collected bone
J. Schilcher, O. Sandberg, H. Isaksson, P. Aspenberg   +3 more
semanticscholar   +1 more source

Rapid severe hypertension and organ damage in two‐kidney two‐clip rats produced by different sizes of clips

Animal Models and Experimental Medicine, EarlyView.
Blood pressure increases immediately when the 2K2C rats (made with 0.3, 0.25, and 0.2 mm U‐shaped clips) regain consciousness from anesthesia. 100% of the rats develop hypertension on the day of 2K2C surgery. Blood pressure continues to rise, resulting in severe hypertension and organ damage to the brain, heart, aorta, and kidneys at 1, 2, 4, and 6 ...
Jia‐Sheng Tian, Qi‐Sheng Ling, Yu‐Chen Wei, Dao‐Xin Wang, Chao‐Yu Miao   +4 more
wiley   +1 more source

Endoprosthetic Reconstruction for a Displaced Atypical Femoral Fracture in a Cancer Patient with Poor Prognosis

Case Reports in Orthopedics, 2018
Zoledronate or denosumab treatment is beneficial for cancer patients with bone metastasis. However, each agent may trigger atypical femoral fractures.
Hironari Tamiya, Hiroki Hagizawa, Takaaki Nakai, Yoshinori Imura, Takaaki Tanaka, Kazuya Oshima, Toshikazu Ito, Norifumi Naka, Shigeyuki Kuratsu   +8 more
doaj   +1 more source