Results 141 to 150 of about 205,023 (305)

DEL‐1 is an Endogenous Senolytic Protein that Inhibits Senescence‐Associated Bone Loss

open access: yesAdvanced Science, EarlyView.
Senescent bone marrow stromal cells accumulate in the aging bone microenvironment, promoting bone degeneration. DEL‐1, an endogenous secreted protein, acts as a natural senolytic that selectively eliminates these cells. By engaging a β3 integrin/CD73/adenosine/p38 MAPK/BCL‐2 pathway, DEL‐1 counters aging‐related bone loss, revealing promising ...
Jong‐Hyung Lim   +11 more
wiley   +1 more source

Wedelolactone, a Novel TLR2 Agonist, Promotes Neutrophil Differentiation and Ameliorates Neutropenia: A Multi‐Omics Approach to Unravel the Mechanism

open access: yesAdvanced Science, EarlyView.
Wedelolactone (WED), a natural TLR2 agonist, promotes neutrophil differentiation and enhances bactericidal function, offering a potential therapeutic strategy for neutropenia. Using a multi‐omics approach, this study reveals that WED activates the TLR2/MEK/ERK pathway, upregulating key transcription factors (PU.1, CEBPβ) to drive neutrophil development.
Long Wang   +16 more
wiley   +1 more source

Challenging the myth: comparing early complications of native and periprosthetic distal femur fractures. The role of implant stability. [PDF]

open access: yesArch Orthop Trauma Surg
Lampert C   +7 more
europepmc   +1 more source

Relationship between Plate Length and Fracture Height as a Predictor of Non-Union in Distal Femur Fractures. A Restrospective Study [PDF]

open access: hybrid, 2020
Alvaro Martínez-Ayora   +5 more
openalex   +1 more source

Wearable and Implantable Devices for Continuous Monitoring of Muscle Physiological Activity: A Review

open access: yesAdvanced Science, EarlyView.
Recent advances in materials and device engineering enable continuous, real‐time monitoring of muscle activity via wearable and implantable systems. This review critically summarizes emerging technologies for tracking electrophysiological, biomechanical, and oxygenation signals, outlines fundamental principles, and highlights key challenges and ...
Zhengwei Liao   +4 more
wiley   +1 more source

Sensitivity analysis diagram of the impact of tennis on left femur BMD in male.

open access: green
Huang Huiwen (22120607)   +4 more
openalex   +1 more source

Reliability of measuring lateral bowing angle of the femur in patients with atypical femur fractures [PDF]

open access: gold, 2019
Young‐Kyun Lee   +5 more
openalex   +1 more source

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