Results 141 to 150 of about 493,797 (347)

Numerical evaluation of wearing pressure and cloth stiffness on vibration of human skeletal muscle during athletic movement [PDF]

open access: yes, 2019
In the design of sportswear which is expected to modify the performance of athletes, it is important to clarify the effects of the wear's rigidity and wearing pressure on the vibrations during exercise because they have been considered to reduce the ...
Sakuma, Atsushi, Ueda, Shodai
core  

Bifidobacterium Pseudolongum‐Derived Acetate Attenuates Acute Pancreatitis Through GPR43‐Mediated Suppression of M1 Macrophage Polarization

open access: yesAdvanced Science, EarlyView.
The severity of acute pancreatitis (AP) is linked to reduced abundance of Bifidobacterium pseudolongum (B. pseudolongum). Administration of B. pseudolongum or its key metabolite acetate alleviates pancreatic and systemic inflammation by suppressing M1 macrophage polarization.
Langyi Guan   +16 more
wiley   +1 more source

Computer vs human: Deep learning versus perceptual training for the detection of neck of femur fractures

open access: yesJournal of Medical Imaging and Radiation Oncology, 2019
M. Adams   +5 more
semanticscholar   +1 more source

Distinct Immunomodulatory Strategies Guide Mesenchymal Stromal/Stem Cell‐Mediated Bone Regeneration

open access: yesAdvanced Science, EarlyView.
Bone regeneration by mesenchymal stem cells is strongly influenced by immune signals. This study shows that priming stem cells with regulatory immune cells or an inflammation‐resolving lipid molecule enhances bone formation through distinct immune pathways.
Salwa Suliman   +5 more
wiley   +1 more source

FRACTURES OF THE FEMUR

open access: yesAnnals of Surgery, 1916
This paper will treat the subject of simple fractures of the shaft of the femur in a general manner, laying down the principles applicable to the management of fractures in the several regions of the bone, or divisions ordinarily designated in the study and treatment of fractures of the femur.
openaire   +3 more sources

Delivery of Pleckstrin‐Homology Domains Suppresses PI3K/Akt Signaling and Breast Cancer Metastasis

open access: yesAdvanced Science, EarlyView.
Current therapies curb tumor growth but not metastasis. Obscurin, a giant metastasis suppressor lost in breast cancer, restrains PI3K/Akt signaling but is impractical to restore. We deploy a mini‐obscurin, comprising the obscurin‐PH‐domain, which sequesters PI3K‐p85, potently suppressing invasion and metastasis.
Matthew Eason   +12 more
wiley   +1 more source

Population-based epidemiology and incidence of distal femur fractures

open access: yesInternational Orthopaedics, 2017
Rasmus Elsøe   +2 more
semanticscholar   +1 more source

Context‐Dependent Role of GDF15: GDF15+ Tumor‐Associated Macrophages Suppress OSCC Progression by Enhancing Phagocytosis

open access: yesAdvanced Science, EarlyView.
This study identifies GDF15+ TAMs as a cell subset mediating tumor regression after immunotherapy. Macrophage‐intrinsic GDF15 enhances phagocytosis and antigen cross‐presentation to CD8+ T cells through the NF‐κB signaling pathway, thereby inhibiting tumor progression.
Xinyu Zhou   +9 more
wiley   +1 more source

Closing-Wedge Distal Femoral Osteotomies- Retrospective Study

open access: yesRevista Brasileira de Ortopedia
Objective To describe the surgical technique of distal closing-wedge femoral osteotomy and a cases series submitted to this technique. Methods A total of 26 patients submitted to medial closing-wedge distal femoral osteotomy from 2002 to 2013 were ...
Pedro Barreira Cabral   +5 more
doaj   +1 more source

PAF Triggered Pyroptotic NETosis Aggravates Myocardial Ischemia/Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
Platelet activating factor (PAF) secreted by cardiomyocytes during MI/R, drives NETs formation and subsequent NETosis. PAF/NETosis signaling activation is an initiative and causal factor in driving MI/R injury. This study identifies dapagliflozin as a potent NETosis inhibitor, and demonstrates that manipulating PAF‐NETosis signal by dapagliflozin or ...
Jiawei Wu   +11 more
wiley   +1 more source

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