Results 151 to 160 of about 205,023 (305)

Skeletal Muscle HSF1 Alleviates Age‐Associated Sarcopenia and Mitochondrial Function Decline via SIRT3‐PGC1α Axis

Advanced Science, EarlyView.
Aged HSF1 muscle‐specific knockout mice show deteriorated muscle atrophy and metabolic dysfunction, while active HSF1 overexpression improves muscle function via activating SIRT3 to deacetylate both PGC1α1 and PGC1α4, which boosts mitochondrial function and muscle hypertrophy in a fiber‐type specific manner, and induces FNDC5/Irisin for tissue ...
Jun Zhang, Min Hu, Xia Wu, Mingwei Guo, Ying Ma, Jin Qiu, Siqi Wang, Yuxiang Cao, Yinzhao Zhong, Fangfang Chen, Yiwen Wang, Wei Wei, Yan Lu, Yong Zhang, Junjie Xiao, Zhenji Gan, Cheng Hu, Xinran Ma, Lingyan Xu   +18 more
wiley   +1 more source

Evaluation and Categorization of Femur Morphometry with Digital Measurement Method

, 2019
Gamze Taşkın Şenol, Ahmet Hilmi Yücel   +1 more
openalex   +1 more source

Finite element modeling of proximal femur with quantifiable weight-bearing area in standing position [PDF]

, 2020
Peng Yang, Tianye Lin, Jingli Xu, Hui-Yu Zeng, Da Chen, Bing-Lang Xiong, Fengxiang Pang, Zhenqiu Chen, Wei He, Qiushi Wei, Qingwen Zhang   +10 more
openalex   +1 more source

Targeting Itga8 Mitigates Neurogenic Bladder Fibrosis Driven by Trem2⁺ Macrophage‐Derived Fn1 via FAK/RhoA/ROCK Signaling

Advanced Science, EarlyView.
Normal bladders exhibit quiescent fibroblasts/macrophages, whereas neurogenic bladders show acute‐phase Itga8⁺ fibroblast expansion driven by Trem2⁺ macrophage‐secreted Fn1, which activates FAK/RhoA/ROCK signaling, promotes cytoskeletal remodeling, and upregulates pro‐fibrotic genes.
Jiaxin Wang, Siyuan Wang, Lida Ren, Xinqi Liu, Lei Zhang, Peng Hu, Wenchao Xu, Shuaixiang Zheng, Jihong Liu, Qing Ling   +9 more
wiley   +1 more source

Acute Correction of Acquired Genu Valgum Secondary to Post-Traumatic Growth Arrest at the Time of Distal Femur Fracture. [PDF]

J Am Acad Orthop Surg Glob Res Rev
Wolf J, Pelz N, Mansour A, Iobst C, Kadado A.   +4 more
europepmc   +1 more source

Comparative analysis of bone regeneration in critical-sized defects using self-assembling peptide hydrogel-178, bone morphogenetic protein-2, and calcium phosphate scaffolds in a rat femur model.

Ippei Yamauchi, Hiroaki Nakashima, Sadayuki Ito, Naoki Segi, Jun Ouchida, Yoshinori Morita, Yukihito Ode, Yasuhiro Nagatani, Yuya Okada, Kei Ando, Shiro Imagama   +10 more
openalex   +2 more sources

Open Transcervical Fracture of Femur Resulted from Gunshot Injury: A Case Report [PDF]

, 2018
Chan Ho, Chan Kin-yan Kenneth, Ip Ka-Chun, Wilson Li   +3 more
openalex   +1 more source

Postoperative Stress Accelerates Atherosclerosis Through Inflammatory Remodeling of the HDL Proteome and Impaired Reverse Cholesterol Transport

Advanced Science, EarlyView.
The study shows that noncardiac surgical inflammation rapidly disrupts HDL function and cholesterol efflux in mice and human patients. Impaired reverse cholesterol transport after surgery drives rapid lipid accumulation, NETosis, and apoptosis within atherosclerotic plaques.
Dominique M. Boucher, Victoria Lorant, Valerie Rochon, Abigail Carter, Cameron Stotts, My‐Anh Nguyen, Thomas Laval, Christina Emerton, Nathan Joyce, Nysa Vinayak, Marlena Scaffidi, David Cook, Katey J. Rayner, Rebecca C. Auer, Scott M. Gordon, Mireille I. Ouimet   +15 more
wiley   +1 more source

PATTERNS AND SHORT OUTCOMES OF PROXIMAL FEMUR FRACTURE IN SKELETALLY MATURE PATIENTS

*1Dr. Mustafa Ammar Dahham, 2Dr. Mubder A. Mohammed Saeed, 3Dr. Falih Waheed Hashim
openalex   +1 more source

A Case of Enchondromatosis Treated by Correction Osteotomy for Valgus Deformity of the Femur

, 2009
Masato Tomita, Kenji Kumagai, Takayuki Nakamura, Takayuki Shida, Tomonori Yanai, Hiroyuki Shindo   +5 more
openalex   +2 more sources