Results 11 to 20 of about 2,490 (179)

Investigation of Fenbendazole Solubility Using Particle Size Reduction Methods in the Presence of Soluplus^® [PDF]

Pharmaceutics
Background/Objectives: Fenbendazole is a potential cancer treatment and a proven antiparasitic in veterinary applications. However, its poor water solubility limits its application.
Amirhossein Karimi, Pedro Barea, Óscar Benito-Román, Beatriz Blanco, María Teresa Sanz, Clement L. Higginbotham, John G. Lyons   +6 more
doaj   +2 more sources

Solid Dispersions of Fenbendazole with Polymers and Succinic Acid Obtained via Methods of Mechanochemistry: Their Chemical Stability and Anthelmintic Efficiency

Powders, 2023
The substance fenbendazole is included in the composition of many anthelmintic drugs, in which the “chemical stability” parameter is one of the main characteristics when obtaining permission for the use of drugs in veterinary practice.
Salavat S. Khalikov, Ekaterina A. Khakina, Marat S. Khalikov, Anastasiya I. Varlamova   +3 more
doaj   +1 more source

Pharmacological activity and targeted delivery of supramolecular fenbendazole obtained by mechanochemical technology with various components

Российский паразитологический журнал, 2021
The purpose of the research is studying the influence of various components on the targeted delivery of fenbendazole and evaluation of their efficacy in mice experimentally infected with Trichinella spiralis.Materials and methods.
A. I. Varlamova, I. A. Arkhipov, V. E. Abramov, M. V. Arisov, S. S. Khalikov, A. V. Dushkin   +5 more
doaj   +1 more source

Evaluation of the efficacy of solid dispersion of fenbendazole against different stages of gastrointestinal nematodes of sheep in Samara region

Российский паразитологический журнал, 2023
The purpose of the research is to study the efficacy of a solid dispersion of fenbendazole at different stages of gastrointestinal nematodes of young sheep. Materials and methods.
I. A. Arkhipov, A. I. Varlamova, K. M. Sadov   +2 more
doaj   +1 more source

Risk Assessment of Human Consumption of Meat From Fenbendazole-Treated Pheasants

Frontiers in Veterinary Science, 2021
Fenbendazole is a benzimidazole-class anthelmintic that is used for the control of immature and adult stages of internal parasites, such as nematodes and trematodes, in domestic food-animal species.
Marta Carreño Gútiez, Lisa A. Tell, Beatriz Martínez-López   +2 more
doaj   +1 more source

Impact of fenbendazole resistance in Ascaridia dissimilis on the economics of production in turkeys

Poultry Science, 2021
: Feed conversion efficiency is among the most important factors affecting profitable production of poultry.Infections with parasitic nematodes can decrease efficiency of production, making parasite control through the use of anthelmintics an important ...
James B. Collins, Brian Jordan, Anand N. Vidyashankar, Pablo Jimenez Castro, Justin Fowler, Ray M. Kaplan   +5 more
doaj   +1 more source

Biological Activity of Fenbendazole Solid Dispersion Obtained by Mechanochemical Technology with Various Components for Targeted Delivery

Российский паразитологический журнал, 2020
The purpose of the research is studying anthelmintic efficacy of fenbendazole solid dispersion obtained by mechanochemical technology with various components for targeted delivery.Materials and methods.
A. V. Varlamova
doaj   +1 more source

Anthelmintic efficiency of doramectin, fenbendazole, and nitroxynil, in combination or individually, in sheep worm control

Revista Brasileira de Parasitologia Veterinária, 2016
The anthelmintic efficiency of doramectin, fenbendazole, and nitroxynil, used individually or in combination, was determined by the Fecal Egg Count Reduction (FECR) test and cultivation of larvae of anthelminthic-treated sheep grouped as follows: G1 ...
Luciane Holsback, Pedro Alex Ramsey Luppi, Camile Sanches Silva, Gustavo Kremer Negrão, Gabriel Conde, Hugo Vinícius Gabriel, João Vitor Balestrieri, Lucas Tomazella   +7 more
doaj   +1 more source

Drug-Induced Liver Injury in a Patient with Nonsmall Cell Lung Cancer after the Self-Administration of Fenbendazole Based on Social Media Information

Case Reports in Oncology, 2021
Fenbendazole is a benzimidazole anthelmintic agent, with a broad antiparasitic range in animals such as dogs and pigs. The agent is also reported to exert antitumor effects and inhibit microtubule-associated tubulin polymerization, but its safety and ...
Teppei Yamaguchi, Junichi Shimizu, Yuko Oya, Yoshitsugu Horio, Toyoaki Hida   +4 more
doaj   +1 more source

DETERMINATION OF FENBENDAZOLE AND ITS METABOLITES IN MILK BY THE METHOD OF LIQUID CHROMATOGRAPHY COUPLED WITH TANDEM MASS SPECTROMETRY

Российский паразитологический журнал, 2016
Objective of research: Development of methods for the determination of fenbendazole and its metabolites in milk by liquid chromatography coupled with tandem mass spectrometry.Materials and methods: Fenbendazole was administered orally to five cows ...
P. P. Kochetkov, A. I. Varlamova, V. E. Abramov, N. S. Misura, E. V. Abramova, S. B. Abramov, N. I. Koshevarov, I. A. Arkhipov   +7 more
doaj   +1 more source