Protective effects of different doses of inhaled fenoterol on methacholine-induced bronchoconstriction in asthmatic children [PDF]
São Paulo Medical Journal, 1998 OBJECTIVE: To evaluate the protective effect of different doses of inhaled fenoterol (F) on bronchoconstriction induced by methacholine (M). DESIGN: randomized double-blind study. SETTING: Referrence center. PARTICIPANTS: 9 children (aged from 7 to 15
Irma Douglas Gomez +4 more
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Hemi-Babim and Fenoterol as Potential Inhibitors of MPro and Papain-like Protease against SARS-CoV-2: An In-Silico Study [PDF]
Medicina, 2022 The coronaviruses belong to the Coronaviridae family, and one such member, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), is causing significant destruction around the world in the form of a global pandemic.
Ahmad Alzamami +6 more
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Intelligent spectrophotometric resolution platforms for the challenging spectra of ipratropium and fenoterol in their combination inhaler with ecological friendliness assessment [PDF]
Scientific ReportsAsthma and chronic obstructive pulmonary disease (COPD) are the most common diagnoses for adults and children with respiratory tract inflammation. Recently, a novel fixed dose combination consisting of Ipratropium and Fenoterol has been released for the ...
Salma N. Ali +3 more
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Ecofriendly colorimetric set-up coupled with mathematical filtration strategy for simultaneous determination of ipratropium and fenoterol in their novel anti-asthmatic metered dose inhaler [PDF]
BMC ChemistryIpratropium bromide (IPR) and fenoterol hydrobromide (FEN) are well-known medications for treating asthma and chronic obstructive pulmonary disease (COPD).
Salma N. Ali +3 more
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Neuroprotective effects of phenylacetylglycine via β2AR on cerebral ischemia/reperfusion injury in rats [PDF]
Saudi Pharmaceutical JournalPhenylacetylglycine (PAGly) is a small molecule derived from phenylalanine in the gut via glycine degradation and conjugation. It has been associated with both the progression of atherosclerosis and protective effects on the myocardium.
Wenjie Hu +4 more
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Biomedicines, 2022 A hallmark of atrial fibrillation is an excess of spontaneous calcium release events, which can be mimicked by β1- or β2-adrenergic stimulation. Because β1-adrenergic receptor blockers (β1-blockers) are primarily used in clinical practice, we here ...
Sergi Casabella-Ramón +12 more
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Wnt/β-catenin signaling modulates human airway sensitization induced by β2-adrenoceptor stimulation. [PDF]
PLoS ONE, 2014 BACKGROUND: Regular use of β2-agonists may enhance non-specific airway responsiveness. The wingless/integrated (Wnt) signaling pathways are responsible for several cellular processes, including airway inflammation and remodeling while cAMP-PKA cascade ...
Christophe Faisy +6 more
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Increased response to β₂-adrenoreceptor stimulation augments inhibition of IKr in heart failure ventricular myocytes. [PDF]
PLoS ONE, 2012 Increasing evidence indicates that the rapid component of delayed rectifier potassium current (I(Kr)) is modulated by α- and β-adrenergic stimulation.
Hegui Wang +7 more
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Frontiers in Pharmacology, 2021 Organic cation transporter 1 (OCT1, SLC22A1) is localized in the sinusoidal membrane of human hepatocytes and mediates hepatic uptake of weakly basic or cationic drugs and endogenous compounds. Common amino acid substitutions in OCT1 were associated with
Sarah Römer +15 more
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Gi proteins regulate adenylyl cyclase activity independent of receptor activation. [PDF]
PLoS ONE, 2014 BACKGROUND AND PURPOSE: Despite the view that only β2- as opposed to β1-adrenoceptors (βARs) couple to G(i), some data indicate that the β1AR-evoked inotropic response is also influenced by the inhibition of Gi.
Caroline Bull Melsom +5 more
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