Results 71 to 80 of about 5,569 (193)

Progress on the development of Class A GPCR‐biased ligands

British Journal of Pharmacology, Volume 182, Issue 14, Page 3249-3300, July 2025.
Class A G protein‐coupled receptors (GPCRs) continue to garner interest for their essential roles in cell signalling and their importance as drug targets. Although numerous drugs in the clinic target these receptors, over 60% GPCRs remain unexploited. Moreover, the adverse effects triggered by the available unbiased GPCR modulators, limit their use and
Paula Morales, Magdalena M. Scharf, Marcel Bermudez, Attila Egyed, Rafael Franco, Olivia K. Hansen, Nadine Jagerovic, Jan Jakubík, György M. Keserű, Dóra Judit Kiss, Pawel Kozielewicz, Olav Larsen, Maria Majellaro, Ana Mallo‐Abreu, Gemma Navarro, Rubén Prieto‐Díaz, Mette M. Rosenkilde, Eddy Sotelo, Holger Stark, Tobias Werner, Laura M. Wingler   +20 more
wiley   +1 more source

The test for nitric oxide metabolites in the exhaled aircondensate as a method of assessing NO-reactivity of theairways in patients with bronchial asthma

Терапевтический архив, 2003
Aim. To estimate airways NO-reactivity in response to their stimulation with fenoterol in different clinical forms of bronchial asthma (BA). Material and methods. The study included 73 patients with BA: mild disease was in 21, moderate in 24 and severe -
B I Geltser, E E Peteshova, E A Kochetkova, E V Eliseeva   +3 more
doaj  

Modeling fire‐related smoke inhalation injury using the human lung‐on‐a‐chip and organoid platform: Pathogenesis insights and therapeutic evaluation

VIEW, Volume 6, Issue 3, June 2025.
Fire‐related smoke inhalation‐induced acute lung injury (SI‐ALI) poses a significant public health risk, yet effective treatments are limited due to the lack of suitable models. This study developed a more realistic model of SI‐ALI using organ‐on‐a‐chip and organoid technologies, identified key molecules such as catechol‐O‐methyltransferase and ...
Junmin Li, Dezhong Zhang, Yan Meng, Yongqing Chang, Wenbo Wei, Peng Wu, Lin Peng, Wei Chang, Wei Wang, Jie Huang, Jingjing Fang, Keming Zhu, Xiaojian Wan   +12 more
wiley   +1 more source

Efecto broncodilatador de fenoterol y salbutamol asociados a un corticoide en niños con crisis de asma.

Revista Médica Herediana, 1996
RESUMEN Objetivo: Evaluar los efectos clínicos y colaterales de Fenoterol 100 ug/inh en microdosificador inhalatorio (MDI) con aerocámara y salbutamol 100 ug/inh en MDI con aerocámara ambos asociados a dexametasona endovenosa (0.3 mg/kg) en bolo ...
Raúl Huaman, José Velasco, Ronald Vargas, Alberto Diaz, Alfredo Garcia, Pascual Chiarella, Rafael Whu, Juan Fukuda, Oswaldo Zegarra   +8 more
doaj  

Limited β₂-adrenoceptor haplotypes display different agonist mediated airway responses in asthmatics

Respiratory Research, 2006
Background In vitro and some in vivo studies suggested that genetic haplotypes may have an impact on β2-agonist mediated airway responses in asthmatics.
Hart Guus AM, Weller Frank R, Westland Robert, Wierenga Eddy A, van Veen Anneke, Jansen Henk M, Jonkers René E   +6 more
doaj   +1 more source

Do inhaled beta-agonists control cough in URIs or acute bronchitis? [PDF]

, 2004
Patients who receive inhaled beta-agonists for cough due to acute upper respiratory infections (URI) are just as likely to report a productive cough at 7 days compared with patients treated with placebo (strength of recommendation [SOR]: A, based on a ...
Nashelsky, Joan, Stephens, Mary Maniscalco   +1 more
core  

Eosinophil Apoptosis and Clearance in Asthma [PDF]

, 2013
Peer reviewedPublisher ...
Bickham U.R., Duval E., Fadok V.A., Fadok V.A., Gaipl U.S., Hart S.P., Luttmann W., Meagher L.C., Schwartz B.R., Walsh G.M.   +9 more
core   +3 more sources

Clinical Application Guideline of Combination With Traditional Chinese Medicine and Western Medicine in the Prevention and Treatment of Chronic Obstructive Pulmonary Disease (2024)

Journal of Evidence-Based Medicine, Volume 18, Issue 2, June 2025.
ABSTRACT Aim Chronic Obstructive Pulmonary Disease (COPD) is a common chronic airway disease that can lead to decreased lung function in patients. It places a heavy economic burden on patients and society. Traditional Chinese medicine (TCM) and Western medicine have played important roles in managing COPD.
Di Wu, Wei Liu, Jianxin Wang, Wei Chen, Mengyao Shi, Lu Zhang, Hui Wang, Huanzhang Ding, Xiao Ma, Yating Gao, Zengtao Sun, Jiangtao Lin, Hongchun Zhang, Suyun Li, Zhuying Li, Zhenhui Lu, Fuqiang Wen, Zegeng Li   +17 more
wiley   +1 more source

EVALUASI KUANTITAS PENGGUNAAN OBAT ANTIASMA PADA PASIEN ASMA SERANGAN AKUT DI RUMAH SAKIT PARU RESPIRA YOGYAKARTA

JIIS: Jurnal Ilmiah Ibnu Sina, 2017
Asma adalah penyakit inflamasi kronik saluran napas yang ditandai adanya mengi, batuk, dan rasa sesak di dada akibat penyumbatan saluran napas. Serangan asma bervariasi dari ringan sampai berat bahkan dapat bersifat fatal atau mengancam jiwa (Rai dan ...
Lolita Lolita, Mas Ulfah Lestari
doaj   +3 more sources

Athletes and fenoterol [PDF]

Thorax, 2000
In a review of doping in athletes by Dr Dekhuijzen published recently in Thorax 1 the substance fenoterol was included in table 2 which listed respiratory drugs permitted by the International Olympic Committee (IOC). However, according …
openaire   +2 more sources