Results 11 to 20 of about 16,203 (229)

Impact of hippocampal α-synuclein oligomers on cognitive trajectory in patients with dementia with Lewy bodies. [PDF]

Alzheimers Dement
Increasing evidence indicates that α‐synuclein (αSYN) oligomers are toxic. We sought to determine whether αSYN oligomers were associated with faster cognitive decline in prospectively‐followed patients with dementia with Lewy bodies (DLB).
Sekiya H, Franke L, Ono D, DeTure M, Ross OA, Murray ME, McLean PJ, Ferman TJ, Dickson DW.   +8 more
europepmc   +3 more sources

Eski Hitit Dönemine Ait Bir Ferman

Ankara Üniversitesi Dil ve Tarih-Coğrafya Fakültesi Tarih Bölümü Tarih Araştırmaları Dergisi, 2007
Tawananna\\'nin ve onun cocuklarinin dahi adinin telaffuzunu siddetleyasaklayan, diger orneklerinden farkli icerigi ile dikkati ceken KBo III 27 no\\'lu fermani yazdiran kral I.Hattusili\\'dir. Belgede soz konusu olan Tawananna\\'nin bukralm kiz kardesi olmasi gerektigi, donemin diger metinlerinde yer alan paralel konulara dair kayitlarla ortaya ...
Turgut Yi̇ği̇t
openaire   +4 more sources

FERMAN PADİŞAHINDIR: III. AHMED’İN SAKAL FERMANINA DAİR BİR TARİH MANZUMESİ

HİKMET-Akademik Edebiyat Dergisi (Journal Of Academic Literature), 2020
“Beard” is one of the recurring themes in classic Turkish poetry and in addition to the word sakal, its Turkish equivalent, it is referred to as hat (calligraphic piece), lihye, and rîş. In poetry, it might be considered a positive quality for being an element of beauty and for its religious significance, as well as being used with negative ...
Özlem Düzlü
openaire   +4 more sources

Selçuklu-İlhanlı Devrine Ait Bilinmeyen Bir Ferman

Marmara Türkiyat Araştırmaları Dergisi
Ortaçağ Türk-İslȃm devletlerine ait ancak sınırlı sayıdaki belge zamanın yok edici tahribatından kurtularak günümüze ulaşma imkȃnı bulabilmiştir. Bu çalışmada da ilk defa tanıtılarak, neşir, tercüme ve değerlendirmesi yapılacak olan Selçuklu-İlhanlı devrine ait Farsça bir ferman (misȃl) da bu cümledendir.
Osman Özgüdenli
openaire   +3 more sources

Association between Human Leukocyte Antigen Alleles and Neuropathological Outcomes in Lewy Body Disease. [PDF]

Ann Neurol
Objective Lewy body disease (LBD) is a complex neurodegenerative disorder characterized by the accumulation of misfolded α‐synuclein in the brain. Neuroinflammation has long been implicated in LBD pathogenesis, and recent genetic studies in Parkinson's disease (a clinical manifestation of LBD) have shown consistent association with the human leukocyte ...
Gavrielatos M, Heckman MG, Soto-Beasley AI, Blumenfeld SG, Hou X, Koga S, Murray ME, Kasanuki K, Ono D, Fiesel FC, Uitti RJ, Fields JA, Botha H, Ramanan VK, Kantarci K, Lowe VJ, Jack CR, Ertekin-Taner N, Gibbs JR, Traynor BJ, Dalgard CL, Savica R, Graff-Radford J, Petersen RC, Reichard RR, Graff-Radford NR, Ferman TJ, Boeve BF, Wszolek ZK, Springer W, Gan-Or Z, Mignot E, Scholz SW, Dickson DW, Ross OA.   +34 more
europepmc   +2 more sources

Longitudinal 123I‐FP‐CIT SPECT Analysis Using DaTQUANT Software in Autopsy Confirmed Dementia with Lewy Bodies Patients [PDF]

Alzheimers Dement
Abstract Background Dementia with Lewy Bodies (DLB) has been overlooked or misdiagnosed as Alzheimer's disease (AD) dementia due to its frequent concomitant AD pathology with Lewy Body Disease (LBD) pathology. Although autopsy confirmation has been the gold standard for the precise diagnosis of DLB, time‐course 123I‐FP‐CIT SPECT (DaT‐SPECT) findings in
Miyagawa T, Przybelski S, Vernon C, Min H, Forsberg L, Fields J, McCarter S, Ferman T, Ramanan V, Graff‐Radford J, Jones D, Savica R, Reichard R, Parisi J, Nguyen A, Dickson D, Murray M, Day G, Graff‐Radford N, St. Louis E, Jain M, Kantarci K, Lowe V, Boeve B.   +23 more
europepmc   +4 more sources

Association between visual hallucinations and α-synuclein oligomers in patients with dementia with Lewy bodies. [PDF]

Alzheimers Dement
Abstract INTRODUCTION Visual hallucinations (VHs) represent one of the core clinical features of dementia with Lewy bodies (DLB); however, their underlying pathology remains unclear. METHODS We employed proximity ligation assay (PLA) and phosphorylated α‐synuclein (αSYN) immunohistochemistry to compare αSYN oligomers and Lewy‐related pathology across ...
Sekiya H, Franke L, Ono D, DeTure M, Ross OA, Day GS, Lachner C, Graff-Radford NR, McLean PJ, Ferman TJ, Dickson DW.   +10 more
europepmc   +2 more sources

Substantia Nigra Iron Deposition in Lewy Body Disease: A Magnetic Resonance Imaging and Neuropathology Study. [PDF]

Mov Disord
Abstract Objective To compare iron deposition in the substantia nigra (SN) as measured with quantitative susceptibility mapping (QSM) on antemortem magnetic resonance imaging (MRI) between individuals with and without Lewy‐related pathology at autopsy. Methods We performed a retrospective cohort study including 54 participants who underwent autopsy and
Diaz-Galvan P, Przybelski SA, Lesnick TG, Murray ME, Nguyen A, Reichard RR, Dickson DW, Ono D, Senjem ML, Schwarz CG, Gunter J, Lowe V, Forsberg LK, Fields JA, Savica R, Graff-Radford J, Ramanan VK, Jones D, Botha H, St Louis EK, Knopman D, Day GS, Graff-Radford N, Kremers W, Petersen RC, Jack CR, Ferman TJ, Boeve BF, Kantarci K.   +28 more
europepmc   +2 more sources

NODDI reveals white matter microstructural changes in isolated REM sleep behavior disorder [PDF]

Alzheimers Dement
Abstract Background Isolated REM sleep behavior disorder (iRBD) is a parasomnia that reflects an evolving α‐synucleinopathy disorder, providing an opportunity to study early pathological changes. While diffusion tensor imaging (DTI) studies have shown white matter changes in iRBD, Neurite Orientation Dispersion and Density Imaging (NODDI) may offer ...
Mak E, Przybelski S, Reid R, Fought A, Schwarz C, Vemuri P, Jack C, Nie Y, De La Cruz H, Avidan A, Bliwise D, Campbell M, Criswell S, Davis A, Duff K, Martens K, Elliot J, Ferman T, Fields J, Forsberg L, Gagnon J, Gan‐Or Z, Howell M, Hu M, Hu X, Huddleston D, Kotzbauer P, Langley J, Lim M, Locke J, Lowe V, McCarter S, McLeland J, Miglis M, Mignot E, Miyagawa T, Neilson L, Nichols K, Pelletier A, Ross O, Schenck C, Wolfgang S, St. Louis E, Trotti L, Videnovic A, Xiong C, Postuma R, Ju Y, Boeve B, Kantarci K.   +49 more
europepmc   +2 more sources

Research criteria for the diagnosis of prodromal dementia with Lewy bodies

Neurology, 2020
The prodromal phase of dementia with Lewy bodies (DLB) includes (1) mild cognitive impairment (MCI), (2) delirium-onset, and (3) psychiatric-onset presentations.
I. McKeith, T. Ferman, Alan J. Thomas, F. Blanc, B. Boeve, H. Fujishiro, K. Kantarci, C. Muscio, J. O'Brien, R. Postuma, D. Aarsland, C. Ballard, L. Bonanni, P. Donaghy, M. Emre, J. Galvin, D. Galasko, J. Goldman, S. Gomperts, L. Honig, M. Ikeda, J. Leverenz, S. Lewis, K. Marder, M. Masellis, D. Salmon, John-Paul Taylor, D. Tsuang, Z. Walker, P. Tiraboschi   +29 more
semanticscholar   +1 more source