Results 111 to 120 of about 533,740 (272)
Developing Quorum Sensing‐Based Collaborative Dynamic Control System in Halomonas TD01
Advanced Science, EarlyView.A standardized and streamlined inducer‐free quorum sensing (QS)‐based collaborative dynamic control pattern is developed for sufficient gene expression control in Halomonas TD by mixing two engineered cells, cells A and B. Proof‐of‐concept studies are designed to test the dynamic control performance in mixed cultures in fed‐batch conditions.
Yi‐Na Lin +12 more
wiley +1 more source
Advanced Science, EarlyView.This study shows how selected pericytes outperform stromal cells in promoting angiogenesis as well as vasculogenesis in a microfluidic organ‐on‐a‐chip platform and by whole mRNA sequencing. It demonstrates how pericyte extracellular vesicles, and more specifically interleukin‐6, mediate this angiogenic stimulation.
Julian Gonzalez‐Rubio +9 more
wiley +1 more source
Nudix Hydrolase 13 Impairs the Initiation of Colorectal Cancer by Inhibiting PKM1 ADP‐Ribosylation
Advanced Science, EarlyView.This study identified NUDT13 as a roadblock in the progression from colorectal adenoma to CRC, and revealed that NUDT13 stabilizes PKM1 protein by reducing the PARylation that is catalyzed by PARP1, thereby reprogramming the metabolic propensity of CRC cells.
Jinlong Lin +12 more
wiley +1 more source
LACTATEing Salmonella: A Host-Derived Fermentation Product Fuels Pathogen Growth [PDF]
, 2018 Bärbel Stecher, Kirsten Jung
openalex +1 more source
Advanced Science, EarlyView.The N‐acetyltransferase‐10 (NAT10)‐mediated mRNA N4‐acetylcytidine modification enhances the stability of CXCL2 and KLF5 mRNA. Then, secreted CXCL2 promotes M2 macrophage polarization and oncostatin M secretion, activating NAT10 expression via STAT3 signaling.
Chen Chen +17 more
wiley +1 more source
Products deriving from microbial fermentation are linked to insulinaemic response in pigs fed breads prepared from whole-wheat grain and wheat and rye ingredients [PDF]
, 2010 Peter Kappel Theil +4 more
openalex +1 more source
Gut Microbiota‐Butyrate‐PPARγ Axis Modulates Adipose Regulatory T Cell Population
Advanced Science, EarlyView.This study identifies the indispensable role of gut microbiota in the maintenance of ST2+ adipose Treg cell population, and defines gut microbiota‐derived butyrate as an endogenous PPARγ agonist, modulating adipose Treg cell populations via promoting PPARγ activation. Butyrate or fiber supplementation restores the VAT ST2+ Treg population in obese mice
Banru Chen +16 more
wiley +1 more source
Advanced Science, EarlyView.This study presents engineered probiotics that convert immunosuppressive adenosine into inosine in tumors, alleviating immunosuppression and enhancing antitumor immunity. Demonstrating efficacy in murine ectopic and orthotopic tumor models, this approach offers a promising probiotic‐based cancer immunotherapy strategy, highlighting the potential of ...
Jinhui Wang +11 more
wiley +1 more source
RNAlater facilitates remote sampling of aquaculture Atlantic salmon liver for proteomic analysis
Aquaculture, Fish and Fisheries, Volume 2, Issue 6, Page 578-586, December 2022., 2022 Graphical Abstract Proteomes of similar sizes were obtained in samples preserved by snap‐freezing or RNAlater. Proteins involved in transcriptional and translational machinery were affected in RNAlater stored samples. Abundance of published markers for heat and oxidative stress was not affected by snap‐freezing or RNAlater.
Anca G. Rusu +6 more
wiley +1 more source