Results 71 to 80 of about 200,822 (325)

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Fermentation of Cereals and Legumes: Impact on Nutritional Constituents and Nutrient Bioavailability

Fermentation, 2022
Fermented food products, especially those derived from cereals and legumes are important contributors to diet diversity globally. These food items are vital to food security and significantly contribute to nutrition.
Janet Adeyinka Adebo, Patrick Berka Njobeh, Sefater Gbashi, Ajibola Bamikole Oyedeji, Opeoluwa Mayowa Ogundele, Samson Adeoye Oyeyinka, Oluwafemi Ayodeji Adebo   +6 more
doaj   +1 more source

MOESM1 of Efficient production of α-acetolactate by whole cell catalytic transformation of fermentation-derived pyruvate

, 2019
Additional file 1: Table S1. Primers and gBlock sequence (bl-ALS). Table S2. Catalytic properties of used ALS enzymes. Figures S1-S9. Supplementary results.
Dorau, Robin, Chen, Lin, Liu, Jianming, Jensen, Peter, Solem, Christian   +4 more
openaire   +1 more source

Hydrogen production using Purple Non-Sulfur Bacteria (PNSB) cultivated under natural or artificial light conditions with synthetic or fermentation derived substrates [PDF]

, 2014
The aim of this thesis was to verify the feasibility of the hydrogen production process with purple non sulfur bacteria both under sunlight irradiation in an up-scaled system and with the use of low cost substrates. Among the products offermentations tested the best results were obtained with a medium derived from vegetable wastes.
openaire   +2 more sources

Integrating microalgae production with anaerobic digestion: a biorefinery approach [PDF]

, 2014
This is the peer reviewed version of the following article: [Uggetti, E. , Sialve, B. , Trably, E. and Steyer, J. (2014), Integrating microalgae production with anaerobic digestion: a biorefinery approach. Biofuels, Bioprod. Bioref, 8: 516-529.
Al Seadi, Amaro, Azov, Bchir, Becker, Becker, Belarbi, Benemann, Bjornsson, Cai, Chen, Chen, Cheng, Cherubini, Chisti, Chisti, Cho, Coats, Collet, Coombs, Crofts, De Schamphelaire, Delruea, Dhargalkar, Dismukes, Domozych, Doušková, Ehimen, Ferreira, Frigon, Godfree, González-Fernández, González-Fernández, González-Fernández, Guieysse, Guo, Harun, Harun, Harun, Hidayet, Hw, Kallqvist, Kayhanian, Lakaniemi, Lardon, Li, Marcato, Markou, Mendesa, Meuser, Molinuevo-Salces, Monteiro, Mussgnug, Muñoz, Möller, Naim, Nguyen, Ogbonna, Olguín, Park, Park, Park, Passos, Passos, Perez-Garcia, Phang, Pieber, Pires, Razon, Richmond, Sahlström, Sialve, Singh, Singh, Skjånes, Subhadra, Travieso, Türker, Uggetti, Van der Ha, Wi, Wijffels, Williams, Wu, Wu, Yacoby, Yang, Yang, Yuan, Zamalloa, Zamalloa   +90 more
core   +4 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Study on the Changes of Bone Calcium during the Fermentation of Bone Powders with Different Fermenters

Foods
Two fermenters, Lactobacillus acidophilus (LA) and the active dry yellow wine yeast (HY), were utilized to ferment cattle bones in order to release calcium.
Jia Meng, Ying Wang, Jinxuan Cao, Wendi Teng, Jinpeng Wang, Yuemei Zhang   +5 more
doaj   +1 more source

Combining Cellulosic Ethanol Fermentation Waste and Municipal Solid Waste-derived Fiber with a Kraft Black Liquor-derived Binder for Recycled Paper Making

BioResources, 2015
Rice straw cellulosic ethanol fermentation waste (CEFW) and municipal solid waste derived fiber (MSWF) were used as alternative fibers for recycled paper making.
Chun-Han Ko, Shao-Yuan Leu, Chia-Chi Chang, Ching-Yuan Chang, Yi-Chung Wang, Ya-Nang Wang   +5 more
doaj   +1 more source

Identification and biotechnological characterization of lactic acid bacteria isolated from chickpea sourdough in northwestern Argentina [PDF]

, 2019
Chickpea, a relevant legume worldwide, can be nutritional and functionally improved by fermentation with lactic acid bacteria (LAB). In order to select suitable autochthonous starter cultures, we isolated and identified LAB from kabuli chickpeas ...
Hebert, Elvira Maria, Saavedra, Maria Lucila, Saez, Gabriel Dario, Zarate, Gabriela del Valle   +3 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source