Dissecting the Ecological Structure of Health and Disease in the Global Gut Microbiome
We introduce Wiredancer, a framework that identifies three continuous ecological factors of the gut microbiota. These factors exhibit distinct patterns across health and disease, jointly capturing disrupted ecological stability and offering a new perspective for precision diagnostics and therapeutic strategies.
Baoyuan Zhu +19 more
wiley +1 more source
Intermittent oxygenation during peak fermentation: Effect on fermentation kinetics, volatile composition, and sensory properties. [PDF]
Cui D +6 more
europepmc +1 more source
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang +32 more
wiley +1 more source
Construction of Synthetic Microbial Community with Core Microorganisms for Soy Sauce Fermentation. [PDF]
Chen P, Du G, Chen J, Fang F.
europepmc +1 more source
Cross Kingdom Metabolic Engineering Paradigm Elevating Sustainable Protein Production
ABSTRACT Confronting the dual crisis of escalating global protein demand and unsustainable agriculture necessitates transformative solutions. Here, we pioneer evolutionary insights from maize nitrogen optimization via asparagine synthetase (ASNS) to rewire metabolism in Pichia pastoris.
Yuanyuan Du +4 more
wiley +1 more source
Optimization of solid-state fermentation process of diets and its effects on growth performance and intestinal function in growing pigs. [PDF]
Ji M +8 more
europepmc +1 more source
Nutraceutical potential of rocket (Eruca vesicaria) after bacterial fermentation
openLa fermentazione è una delle tecniche più utilizzate per incrementare la shelf-life degli ali-menti e per migliorarne le caratteristiche sensoriali.
CHINELLO, MANUEL
core
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu +18 more
wiley +1 more source
Lactic Acid Fermentation of Carrot Juice: Effects of LAB Strains, Total Soluble Solids, Inoculum Level, and Fermentation Time. [PDF]
Nguyen TV +5 more
europepmc +1 more source
CD4+ Tregs Drive Post‐Ischemic Sprouting Angiogenesis via Endothelial YY1/MAML1 Reactivation
ABSTRACT Microvascular complications of diabetes are chronic diseases of small vessels. We previously found that CD4+ regulatory T‐cells (Tregs) are markedly reduced in type 2 diabetes (T2D) after ischemic injury in both mice and humans, and that Treg deficiency in immunodeficient mice impairs vascular regeneration.
Hang Qu +10 more
wiley +1 more source

