Results 61 to 70 of about 401,983 (317)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Kinetics of Ethanol Production from Whey by Fermentation using Kluyveromyces marxianus [PDF]

, 2012
Whey is the liquid remaining after milk has been curdled and strained. It is a by-product of the manufacture of cheese or casein and has several commercial uses.
H, Hadiyanto, Dessy , Ariyanti, Desiyantri , Siti Pinundi, Apsari , Puspita Aini, Djoko , Murwono   +4 more
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Review of physiological compounds and health benefits of soybean paste (doenjang): exploring its bioactive components

Journal of Ethnic Foods
This review paper explores the history, cultural significance, and functional characteristics of soybean paste (doenjang) in Korean cuisine. In particular, it covers its origins, cultural importance, production methods, functionalities, and associated ...
Young Kyoung Park, Jinwon Kim, Myeong Seon Ryu, Do-Youn Jeong, Hee-Jong Yang   +4 more
doaj   +1 more source

Optimization of spray drying process of camellia oleifera seed oil microcapsule by response surface methodology

Liang you shipin ke-ji, 2019
On the basis of single factor experiment,the processing technology of microencapsulated camellia oleifera seed oil was optimized by response surface method.The results showed that the optimized parameters were as follows： solid content 19%,inlet air ...
BAO Zhen, LU Qing, ZHANG Liang, XIAO Yong-sheng   +3 more
doaj   +1 more source

Design Process of Ethanol Production by Extractive -Fermentation to Increase The Yield and Productivity of Ethanol [PDF]

, 2012
Ethanol is generally produced by batch fermentation process. However, this process will bring about accumulation of ethanol product which can poison the microorganism and lead to low productivity which finally results in an economical disadvantage.
Ayu Ratna , Permanasari,, Ririn , Indriani AR,, Tri , Widjaja,, Ali , Altway   +3 more
core  

Chemical kinetics and fermentation simulations

, 2021
the thesis is a simulation of fermentation processes and their data analysis with a conclusion about the temperature factorChemical EngineeringBSc ...
Madder, Hamza
core  

Screening of Non- Saccharomyces cerevisiae Strains for Tolerance to Formic Acid in Bioethanol Fermentation [PDF]

, 2015
Formic acid is one of the major inhibitory compounds present in hydrolysates derived from lignocellulosic materials, the presence of which can significantly hamper the efficiency of converting available sugars into bioethanol. This study investigated the
Phister, Trevor G., Oshoma, Cyprian E., Chris Powell, Du Chenyu, Louis, Edward, Chenyu Du, Oshoma Cyprian E., C. Powell (7643243), Cyprian E Oshoma, Greetham, Darren, C. Du (7643246), Darren Greetham, Trevor G Phister, Phister, Trevor, Edward John Louis (7604981), Phister Trevor G., Powell, Chris, Oshoma, Cyprian, Katherine A Smart, K. A. Smart (7630229), Louis, Edward J., T. G. Phister (7630223), Smart, Katherine A., Powell Chris, D. Greetham (7630211), Du, Chenyu, Smart, Katherine, Edward J Louis, Greetham Darren, Smart Katherine A., C. E. Oshoma (7643240), Louis Edward J.   +31 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Bioactivity of tempe by inhibiting adhesion of ETEC to intestinal cells, as influenced by fermentation substrates and starter pure cultures

, 2010
Soya bean tempe is known for its bioactivity in reducing the severity of diarrhoea in piglets. This bioactivity is caused by an inhibition of the adhesion of enterotoxigenic Escherichia coli (ETEC) to intestinal cells.
Nout, M.J.R., Roubos-van den Hil, P.J., Meulen, J., van der, Gruppen, H.   +3 more
core   +1 more source