Results 81 to 90 of about 403,883 (317)
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Liang you shipin ke-ji, 2019 On the basis of single factor experiment,the processing technology of microencapsulated camellia oleifera seed oil was optimized by response surface method.The results showed that the optimized parameters were as follows： solid content 19%,inlet air ...
BAO Zhen +3 more
doaj +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
AMB Express, 2017 Secretion of heterologous proteins into Escherichia coli cell culture medium offers significant advantages for downstream processing over production as inclusion bodies; including cost and time savings, and reduction of endotoxin. Signal peptides play an
SooJin Han +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
SOLID AND LIQUID PINEAPPLE WASTE UTILIZATION FOR LACTIC ACID FERMENTATION USING Lactobacillus delbrueckii [PDF]
, 2007 The liquid and solid pineapple wastes contain mainly sucrose, glucose, fructose and other nutrients. It therefore can potentially be used as carbon source for fermentation to produce organic acid.
Abdullah, Abdullah
core
Enhancing Ethanol Production by Fermentation Using Saccharomyces cereviseae under Vacuum Condition in Batch Operation [PDF]
, 2012 Ethanol is one of renewable energy, which considered being an excellent alternative clean-burning fuel to replaced gasoline. In fact, the application of ethanol as fuel still blended with gasoline. The advantages of using ethanol as fuel are that the raw
Ariyanti, D. (Dessy) +5 more
core +1 more source
The design of unit cells by combining the self-reproduction systems and metabolic cushioning loads
Communications BiologyRecently, we published a comprehensive theoretical analysis of the self-reproduction processes in proto-cells (doubling of their components) composed of different combinations of cellular subsystems.
Kristo Abner +8 more
doaj +1 more source
Influences of Lactate on the High-density Fermentation by Bacillus licheniformis HK
Shipin gongye ke-jiTo improve the biomass and spore rate of Bacillus licheniformis HK, influences of lactate on cell growth and metabolism and spore production were investigated at a 20 L bioreactor, and lactate addition was conducted by coupling with pH7.0 from 16 h to 32
Yanmei ZHAO +6 more
doaj +1 more source