Results 301 to 310 of about 292,601 (358)

p16Ink4a‐Positive Hepatocytes Drive Liver Fibrosis Through Activation of LIFR Family Pathway

Advanced Science, EarlyView.
This study found that, following the long‐term CCl4 treatment, p16high hepatocytes appeared in zone 3, spatially co‐localizing with fibrotic areas. A specific cluster of p16high hepatocytes upregulated CTF1/LIF expression which induced HSC activation and further liver fibrosis, as revealed by single cell transcriptomic analysis.
Koji Nishikawa, Teh‐Wei Wang, Satoshi Kawakami, Shota Tanimoto, Kiyoshi Yamaguchi, Taketomo Kido, Masamichi Kimura, Tsunekazu Hishima, Yuki T. Okamura, Satotaka Omori, Takumi Iritani, Toshikaze Chiba, Takehiro Jimbo, Michio Katano, Kansuporn Kamataki, Ryoichi Yokoyama, Eigo Shimizu, Kiminori Kimura, Satoshi Yamzaki, Seiya Imoto, Yoichi Furukawa, Atsushi Miyajima, Yoshikazu Johmura, Makoto Nakanishi   +23 more
wiley   +1 more source

Effect of Growth Stage on Nutrition, Fermentation Quality, and Microbial Community of Semidry Silage from Forage Soybean. [PDF]

Plants (Basel)
Wang K, Sun S, Zou Y, Gao Y, Gao Z, Wang B, Hua Y, Lu Y, Hu G, Qin L.   +9 more
europepmc   +1 more source

A Hydrodynamic Bioreactor for High‐Yield Production of Extracellular Vesicles from Stem Cell Spheroids with Defined Cargo Profiling

Advanced Science, EarlyView.
This study harnesses hydrodynamic flows to generate, confine and stimulate stem cell spheroids, enabling the large‐scale production of extracellular vesicles (EVs). This innovative method not only streamlines spheroid formation and subsequent EV release in a single, integrated process, but also ensures the generation of EVs with enhanced biological ...
Solène Lenoir, Elliot Thouvenot, Giacomo Gropplero, Léonie Dec, Damarys Loew, Clotilde Théry, Jose E Perez, Claire Wilhelm   +7 more
wiley   +1 more source

Effects of tillage and maturity stage on the yield, nutritive composition, and silage fermentation quality of whole-crop wheat. [PDF]

Front Plant Sci
Xu L, Tang G, Wu D, Han Y, Zhang J.
europepmc   +1 more source

Characterizing Stage‐Specific Cellular Dynamics and Microenvironmental Remodeling in Lung Adenocarcinoma by Single‐Cell RNA Sequencing

Advanced Science, EarlyView.
This study integrated early‐stage patient specimens with publicly available datasets encompassing non‐malignant lung tissues and advanced‐stage LUAD through single‐cell sequencing, revealing a dynamically remodeled tumor microenvironment characterized by a hypoxia‐adapted malignant subset (C5), immunosuppressive LGMN+ macrophages, STAT1‐driven ...
Bomiao Qing, Xiaolan Li, Xiang He, Junyi Wang, Yi Yang, Manling Jiang, Bingbing Yan, Lei Zhang, Anying Xiong, Qin Ran, Guoping Li   +10 more
wiley   +1 more source

Erratum: Utilisation of Lactiplantibacillus plantarum and propionic acid to improve silage quality of amaranth before and after wilting: fermentation quality, microbial communities, and their metabolic pathway. [PDF]

Front Microbiol
Frontiers Production Office.
europepmc   +1 more source

Co-ensiling pomegranate (Punica granatum L.) peels and molasses with berseem (Trifolium alexandrinum L.) alters fermentation quality, nutrient composition, ruminal fermentation and methane production in buffalo bulls in-vitro. [PDF]

Trop Anim Health Prod
Ahmed MG, El-Zarkouny SZ, Al-Sagheer AA, Elwakeel EA.   +3 more
europepmc   +1 more source

Cytokinins affect Fermentation Product Accumulation, Vitamin C Reservation and Quality of Stored Broccoli in Modified Atmosphere Packages

, 2008
Fariba Khalili, M Shekarchi, Y. Mostofi, M Pirali-Hamedani, Noushin Adib   +4 more
openalex   +1 more source

Bacillus velezensis promotes the proliferation of lactic acid bacteria and influences the fermentation quality of whole-plant corn silage. [PDF]

Front Plant Sci
Wang Y, Ying G, Zhang Z, Tang Y, Zhang Y, Chen L.   +5 more
europepmc   +1 more source