Results 41 to 50 of about 10,590 (289)

Mitochondrial ferredoxin determines vulnerability of cells to copper excess [PDF]

, 2017
The essential micronutrient copper is tightly regulated in organisms, as environmental exposure or homeostasis defects can cause toxicity and neurodegenerative disease.
Avery, Simon V., Holland, Sara L., Vallières, Cindy   +2 more
core   +3 more sources

Ferredoxin binding site on ferredoxin: NADP⁺ reductase [PDF]

European Journal of Biochemistry, 1993
The chloroplast enzyme ferredoxin:NADP+ reductase (FNR) catalyzes the reduction of NADP+ by ferredoxin (Fd). FNR and Fd form a 1:1 complex that is stabilized by electrostatic interactions between acidic residues of Fd and basic residues of FNR. To localize lysine residues at the Fd binding site of FNR, the FNR:Fd complex (both proteins from spinach ...
I, Jelesarov, A R, De Pascalis, W H, Koppenol, M, Hirasawa, D B, Knaff, H R, Bosshard   +5 more
openaire   +2 more sources

Structure of the atypical bacteriocin pectocin M2 implies a novel mechanism of protein uptake [PDF]

, 2014
The colicin-like bacteriocins are potent protein antibiotics that have evolved to efficiently cross the outer membrane of Gram-negative bacteria by parasitizing nutrient uptake systems.
Adams, Barreteau, Barreteau, Barreteau, Barreteau, Bernadó, Brookes, Buchanan, Cascales, Chen, Clarke, Denayer, Devanathan, Durand, Elfarash, Emsley, Faraldo-Gomez, Fyfe, Grinter, Grinter, Grinter, Helbig, Housden, Housden, Incardona, Jakes, Kleanthous, Konarev, Laskowski, Lloyd, Loftus, Lukacik, McCoy, Michel-Briand, Murshudov, Noinaj, Noinaj, Patzer, Petoukhov, Rai, Rambo, Riley, Shirvanyants, Svergun, Svergun, Udho, Udho, Usher, Wandersman, Winn, Zeth   +50 more
core   +3 more sources

Two distinct ferredoxins are essential for nitrogen fixation by the iron nitrogenase in Rhodobacter capsulatus

mBio
Nitrogenases are the only enzymes able to fix gaseous nitrogen into bioavailable ammonia and hence are essential for sustaining life. Catalysis by nitrogenases requires both a large amount of ATP and electrons donated by strongly reducing ferredoxins or ...
Holly Addison, Timo Glatter, Georg K. A. Hochberg, Johannes G. Rebelein   +3 more
doaj   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Minimal ATP‐Independent N2‐Reducing Systems Defined by L‐Cluster‐Bound Nitrogenase Assembly Platforms

Angewandte Chemie, EarlyView.
Association of the L‐cluster with the nitrogenase assembly proteins NifEN (NifENL) or NifB (NifBL) intrinsically endows these proteins with N2‐reducing activity, enabling in vitro N2‐reduction by NifENL and NifBL when supplied with chemical reductants or photoexcited quantum dots while supporting in vivo N2‐fixation in NifENL‐ and NifENL‐expressing ...
Robert Quechol, Yimo Yang, Chi Chung Lee, Markus W. Ribbe, Yilin Hu   +4 more
wiley   +2 more sources

Isolation and Characterization of Single and Sulfide‐Bridged Double [4Fe–4S] Cubane Clusters with 4‐Pyridinethiolato Ligands [PDF]

, 2013
Cuboidal iron–sulfur clusters, [4Fe–4S], are important electron‐transfer (ET) sites in biology. In addition, more complex structures, usually consisting of modified or fused cubane clusters, are used as active sites in many important enzymes. For example,
Coucouvanis, Dimitri, Gerlach, Deidra L., Kampf, Jeff, Lehnert, Nicolai   +3 more
core   +1 more source

Light Activated Induction of Cuproptosis in Resistant Cancer Cells Using Polymeric BODIPY Nanoparticles for Photoactivated Chemotherapy

Advanced Functional Materials, EarlyView.
This article presents a photo‐responsive nanoparticle platform that precisely triggers copper‐dependent cuproptotic cell death in (drug‐resistant) cancer cells. The system remains stable and inactive in the dark but releases cytotoxic species upon red‐light irradiation, achieving potent activity in drug‐resistant breast cancer cells.
Ricarda Zimmermann, Nicolás Montesdeoca, Johannes Karges   +2 more
wiley   +1 more source

Growth-promoting effect on iron-sulfur proteins on axenic cultures of Entamoeba dispar

Parasite, 2006
A growth-promoting factor (GPF) that promotes the growth of Entamoeba dispar under axenic culture conditions was found in fractions of mitochondria (Mt), hydrogenosomes (Hg) and chloroplasts (Cp) obtained from cells of six different protozoan, mammalian ...
Khalifa S.A.M., Imai E., Kobayashi S., Haghighi A., Hayakawa E., Takeuchi T.   +5 more
doaj   +1 more source

Unique flexibility in energy metabolism allows mycobacteria to combat starvation and hypoxia. [PDF]

PLoS ONE, 2010
Mycobacteria are a group of obligate aerobes that require oxygen for growth, but paradoxically have the ability to survive and metabolize under hypoxia. The mechanisms responsible for this metabolic plasticity are unknown.
Michael Berney, Gregory M Cook
doaj   +1 more source