Results 101 to 110 of about 123,714 (295)

Identification of a l‐Threonine‐Utilizing Hydrazine Synthetase for Thrazarine Biosynthesis in Streptomyces coerulescens MH802‐fF5

open access: yesChemBioChem, EarlyView.
A putative thrazarine biosynthetic gene cluster is discovered in the genome sequence of Streptomyces coerulescens MH802‐fF5. In vivo and in vitro analyses of ThzN, a hydrazine synthetase with cupin and methionyl‐tRNA synthetase‐like domains encoded in the cluster, showed that it synthesizes a key intermediate of thrazarine by catalyzing condensation ...
Yusuke Shikai   +4 more
wiley   +1 more source

Inflammation is not the cause of an elevated serum ferritin in non-alcoholic fatty liver disease

open access: yesAnnals of Hepatology, 2014
Background. In non-alcoholic fatty liver disease (NALFD), it has often been assumed that an elevation in serum ferritin is likely related to inflammation rather than iron overload.Material and methods.
Melanie D. Beaton   +2 more
doaj  

ELECTRON MICROSCOPIC STUDIES OF EXPERIMENTAL NEPHRITIS WITH FERRITIN-CONJUGATED ANTIBODY [PDF]

open access: bronze, 1963
Giuseppe A. Andres   +4 more
openalex   +1 more source

Manganese Neurotoxicity and Familial Disorders of Manganese Transport

open access: yesAnnals of the Child Neurology Society, EarlyView.
ABSTRACT Manganese is the 12th most common element in the Earth's crust and is an essential industrial component. Biologically, this metal plays an important role as a constituent of numerous enzymes. While manganese is required for normal biochemical and physiological processes, manganese excess can lead to significant toxicity, particularly to the ...
Sidney M. Gospe Jr.
wiley   +1 more source

Extracellular vesicles-derived ferritin from lipid-induced hepatocytes regulates activation of hepatic stellate cells

open access: yesHeliyon
Introduction: and objectives: Extracellular vesicles (EVs) have emerged as key players in intercellular communication within the context of non-alcoholic fatty liver disease (NAFLD).
Mengxue Sun   +11 more
doaj  

Hallmarks of Neuroblastoma—Pathophysiology, Diagnosis, and Therapeutic Interventions

open access: yesCancer Nexus, EarlyView.
ABSTRACT Neuroblastoma, the most common extracranial solid tumor in childhood, continues to challenge clinicians and researchers because of its heterogeneous nature and complex pathophysiology. Recent breakthroughs in molecular profiling revealed intricate genetic alterations driving tumor progression, necessitating an updated perspective on the ...
Abhimanyu Thakur, Anne Dijkstra
wiley   +1 more source

Relationship between serum ferritin and proinflammatory markers in late pregnancy: An exploratory analysis from Cartagena, Colombia

open access: yesBiomédica: revista del Instituto Nacional de Salud
Introduction. In a previous study, we identified an inverse relationship between adverse perinatal outcomes and iron status during late pregnancy of women recruited from a maternal hospital in Cartagena, Colombia.
Alejandra Puerto   +4 more
doaj   +1 more source

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