Results 81 to 90 of about 168,132 (304)

Design and Application of Nanozymes: Current Trends and Cutting‐Edge Breakthroughs

Advanced Science, EarlyView.
Kelong Fan, Hui Wei, Xiyun Yan
wiley   +1 more source

Magnetically Guided Macrophage Immunobots Coordinate Iron‐Metabolic Cascades and Immunogenic Ferroptosis for Tumor Immunotherapy

Advanced Science, EarlyView.
Magnetically guided macrophage immunobots integrate active tumor targeting with immunometabolic therapy. After systemic administration, magnetic actuation enhances immunobot retention and tumor penetration, while LPS‐functionalized FePt microrollers sustain M1‐like polarization through inflammatory and iron‐amplified oxidative signaling and trigger ...
Xirui Zeng, Yingfei Zhang, Chong Wu, Qijia Duan, Mengqi Fan, Kuan Wang, Shirong Cai, Immihan Ceren Yasa   +7 more
wiley   +1 more source

Spatial Au+ Mapping Reveals a Self‐Amplifying Anti‐Tumor Immunity Loop Driven by Au(I) Complexes

Advanced Science, EarlyView.
The first report of spatial Au+ mapping of a representative gold complex (Au9). Macrophages, DCs, and tumor cells ranked as the top three in Au+ enrichment after Au9 treatment. Interestingly, Au9 treatment could induce ferroptosis and suppress cellular cholesterol, further eliciting a self‐amplifying anti‐tumor immunity loop.
Zhongren Xu, Zhiyue Fan, Lin Lv, Wei Lu, Zhenfan Wen, Wukun Liu   +5 more
wiley   +1 more source

Extracellular vesicles-derived ferritin from lipid-induced hepatocytes regulates activation of hepatic stellate cells

Heliyon
Introduction: and objectives: Extracellular vesicles (EVs) have emerged as key players in intercellular communication within the context of non-alcoholic fatty liver disease (NAFLD).
Mengxue Sun, Min Tang, Yiting Qian, Guannan Zong, Gaowang Zhu, Yan Jiang, Yingjie Mu, Minjun Zhou, Qin Ding, Hao Wang, Fengshang Zhu, Changqing Yang   +11 more
doaj   +1 more source

Elevated serum ferritin: what should GPs know?

, 2012
Background Elevated serum ferritin is commonly encountered in general practice. Ninety percent of elevated serum ferritin is due to noniron overload conditions, where venesection therapy is not the treatment of choice.
Bentley, Peter, Olynyk, John, Hazeldine, S., Olynyk, J., Hazeldine, Simon, Goot, K., Crawford, D., Bentley, P., Goot, Katie, Crawford, Darrell   +9 more
core  

Comparison of Magnetic Properties of Polysaccharide Iron Complex (P.I.C.) and Ferritin [PDF]

, 1994
The synthetic polysaccharide iron complex (PIC) molecule has been suggested as a ‘biomimic’, i.e. a counterpart, to the naturally occurring biological molecule ferritin with respect to its magnetic properties based on the identification of ferrihydrite ...
Frankel, Richard B., Mohie-Eldin, M. E. Y., Gunther, L.   +2 more
core   +1 more source

PLXDC2 siRNA‐Mediated Intervention Attenuates Microglial Senescence Through cGAS‐STING Signaling

Advanced Science, EarlyView.
PLXDC2 was identified as a microglial target in Parkinson's disease through human and mouse single‐cell analyses. Ferritin‐armed biomimetic nanovesicles delivered PLXDC2 siRNA, deferoxamine, and CeO2 nanoparticles across the blood–brain barrier, reducing cGAS‐STING activation, iron burden, oxidative stress, and senescence in microglia, thereby ...
Heyue Lu, Zitian Zheng, Feiran Wang, Huanhuan Luo, Fei Ju, Yucheng Zhu, Zheng Zhou, Jie Sun, Zhenghui Qiu, Xiang Luo, Zhongzheng Jia, Jianquan Wang, Hongjie Huang, Bo Zhang   +13 more
wiley   +1 more source

The Role of Ferritin in the Body [PDF]

Ferritin, a crucial iron-storage protein, plays a vital role in controlling iron homeostasis, safeguarding cells from iron-induced oxidative damage, and facilitating cellular metabolism.
Xidirova, Nigora Xolmurzayevna, Amirqulova, Gulhayo Murodullayevna   +1 more
core  

Magnetoreceptor Promotes Hepatocellular Carcinoma Development and Blunts Sorafenib‐Induced Ferroptosis by Regulating Iron Homeostasis

Advanced Science, EarlyView.
Magnetoreceptor (MagR) regulates iron homeostasis and mitochondrial function in hepatocellular carcinoma (HCC) cells. Specifically, MagR deficiency suppresses tumor cell proliferation, migration, and invasion and enhances sorafenib‐induced ferroptosis through iron accumulation.
Tao Wang, Chenghua Song, Xin He, Mengzhou Wang, Wuming Liu, Xiaolin Wang, Yuanyuan Zhang, Jia Zhang, Lin Zhang, Dan Li, Yu Zhang, Zheng Wu, Yi Lyu, Rongqian Wu   +13 more
wiley   +1 more source

Correlation of serum ferritin levels, in female patients with chronic diffuse hair loss: A cross sectional study

Indian Journal of Health Sciences and Biomedical Research KLEU, 2017
Context: Iron is involved in critical physiological processes within the hair follicle, suggesting that iron deficiency (ID) could disrupt hair synthesis.
Sridevi Ramachandra Raichur, A M Pandit, Anil Malleshappa   +2 more
doaj   +1 more source