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Ferritin‐Hijacking Nanoparticles Spatiotemporally Directing Endogenous Ferroptosis for Synergistic Anticancer Therapy

Advances in Materials, 2022
Existing ferroptosis as an iron‐dependent form of regulated cell death primarily relies on importing exogenous iron. However, the excessive employment of toxic materials may cause potential adverse effects on human health.
Luwen Zhu   +9 more
semanticscholar   +1 more source

Ferritin: A Multifunctional Nanoplatform for Biological Detection, Imaging Diagnosis, and Drug Delivery.

Accounts of Chemical Research, 2021
ConspectusFerritins are spherical iron storage proteins within cells that are composed of a combination of 24 subunits of two types, heavy-chain ferritin (HFn) and light-chain ferritin (LFn).
Ningning Song   +5 more
semanticscholar   +1 more source

Serum Ferritin

CRC Critical Reviews in Clinical Laboratory Sciences, 1979
(1) Brief introduction to iron metabolism and the biochemistry of ferritin. (2) Early studies of circulating ferritin. (3) Methods for measuring serum ferritin concentrations -- immunoradiometric, radioimmuno- and enzyme-linked immuno assays based on liver or spleen ferritin -- an evaluation of these techniques.
Mark Worwood, James D. Cook
openaire   +5 more sources

Mitochondrial ferritin

The International Journal of Biochemistry & Cell Biology, 2004
A novel ferritin type specifically targeted to mitochondria has been recently found in human and mouse. It is structurally and functionally similar to the cytosolic ferritins, well-characterized molecules found in most living systems which are designed to store and detoxify cellular iron.
LEVI S, AROSIO, Paolo
openaire   +4 more sources

Ferritin: The role of aluminum in ferritin function

Neurobiology of Aging, 1991
We previously showed that human brain ferritin (HBF) binds aluminum (Al) in vivo and in vitro and HBF isolated from Alzheimer's brain had more Al bound compared to aged matched controls (7). To further understand the role ferritin may play in Al neurotoxicity, we have studied in vitro the effect of Al on the function of human ferritin isolated from ...
J. G. Joshi, James T. Fleming
openaire   +3 more sources

Electrophoresis of Ferritins

Nature, 1968
ELECTROPHORETIC studies of ferritins—iron containing proteins—from horse, man and HeLa cells have already been recorded1,2. This communication describes the electrophoretic patterns of a plant ferritin known as phytoferritin3 and of ferritins from pig, ox and guinea-pig, compared with human and horse ferritin.
J. Mason, I. Zamiri
openaire   +3 more sources

Dissociation of ferritins

Archives of Biochemistry and Biophysics, 1989
Apoferritins prepared from horse spleen and heart and rat heart and liver were dissociated by treatment with acetic acid (pH 1.3-3.0). Sedimentation velocity studies showed that apoferritins of spleen and liver (16-17 S) and heart (18-19 S) dissociated into material sedimenting near 3.2 S.
Maria C. Linder   +4 more
openaire   +3 more sources

FERRITIN IN SERUM

The Lancet, 1973
FERRITIN is the major iron storage protein in the body. Although it is found in all tissues there is little quantitative information about its distribution.
M. Worwood   +3 more
openaire   +3 more sources

Assessment of serum ferritin as a biomarker in COVID-19: bystander or participant? Insights by comparison with other infectious and non-infectious diseases

Biomarkers, 2020
Background The 2019 coronavirus disease (COVID-19) caused by the SARS-CoV-2 virus has an impact on all aspects of patient care. Serum ferritin generally represents a biomarker of choice when iron deficiency is suspected.
K. Kappert, Amir Jahic, R. Tauber
semanticscholar   +1 more source

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