Results 231 to 240 of about 10,712 (297)

Iron deficiency and iron deficiency anemia in inherited bleeding disorders: common, underrecognized, and undertreated. [PDF]

Res Pract Thromb Haemost
Al-Samkari H.
europepmc   +1 more source

Dose‐dependent impairment of brain functional and microstructural connectivity during leukaemia chemotherapy

British Journal of Haematology, EarlyView.
Prospective functional MRI brain and neurocognitive assessments were performed serially during intensive chemotherapy for a cohort of adults with newly diagnosed acute myeloid leukaemia to elucidate ‘chemobrain’ language phenomena. At completion of consolidation, significant reductions in functional and microstructural connectivity were observed ...
Ashleigh P. Scott, Ada Lo, Ying Xia, Kate Thompson, Harriet Bodimeade, Amir Fazlollahi, Nicholas Weber, Cameron Curley, Stewart Hunt, Kirk Morris, Caroline McNamara, Nilu Perera, Elango Subramoniapillai, Steven W. Lane, Glen A. Kennedy, Olivier Salvado, Javier Urriola, Katie L. McMahon   +17 more
wiley   +1 more source

Human mitochondrial ferritin exhibits highly unusual iron-O₂chemistry distinct from that of cytosolic ferritins

Bradley JM, Bugg Z, Pullin J, Moore GR, Svistunenko DA, Le Brun NE.   +5 more
europepmc   +1 more source

Untangling iron threads: A deep dive into plant intracellular pools. [PDF]

Quant Plant Biol
Leskova A, Xiong TC, Mari S, Curie C.
europepmc   +1 more source

Challenges in Exploiting Human H Ferritin Nanoparticles for Drug Delivery: Navigating Physiological Constraints. [PDF]

Wiley Interdiscip Rev Nanomed Nanobiotechnol
Macone A, Cappelletti C, Incocciati A, Piacentini R, Botta S, Boffi A, Bonamore A.   +6 more
europepmc   +1 more source

Red blood cell membrane proteome as a reporter of disease severity, transfusion impact and genetic background in transfusion‐dependent β‐thalassaemia

British Journal of Haematology, EarlyView.
Summary Omics technologies have transformed research in haemoglobinopathies, yet the proteome of RBCs remains largely unexplored in transfusion‐dependent thalassaemia (TDT). In this proteomic analysis, Red blood cell (RBC) membranes from 48 adults with TDT were compared with healthy controls.
Konstantina Theocharaki, Sophia Delicou, Aikaterini Ntzoura‐Kani, Nikolaos Simantiris, Marianna Politou, Veroniki Komninaka, Martina Samiotaki, Jerome Zoidakis, Marianna H. Antonelou   +8 more
wiley   +1 more source

Yolk proteins of the schistosomiasis vector snail Biomphalaria glabrata revealed by multi-omics analysis. [PDF]

Sci Rep
Habib MR, Bu L, Posavi M, Zhong D, Yan G, Zhang SM.   +5 more
europepmc   +1 more source

Host Ferritin Translocates into the Chlamydial Inclusion: A Clear Alteration in its Subcellular Distribution as a Result of Infection [PDF]

, 2011
Al-Younes, H., Meyer, T.
core   +1 more source

Decreased renal function predicts severe cytokine release syndrome after CAR‐T‐cell therapy for large B‐cell lymphoma

British Journal of Haematology, EarlyView.
Summary Cytokine release syndrome (CRS) remains a major toxicity of chimeric antigen receptor (CAR) T‐cell therapy in large B‐cell lymphoma (LBCL), and robust pre‐infusion predictors are needed for risk‐adapted management. We retrospectively analysed LBCL patients in the Japanese nationwide registry who underwent CD19 CAR‐T‐cell therapy between 2019 ...
Yasuyuki Arai, Tomoyasu Jo, Takayuki Sato, Masatoshi Sakurai, Daisuke Kaji, Toshio Kitawaki, Kazuyuki Shimada, Tatsu Shimoyama, Satoshi Yoshihara, Shinichi Makita, Nobuharu Fujii, Go Yamamoto, Keisuke Kataoka, Emiko Sakaida, Hideki Goto, Yasuhiro Nakashima, Akiyo Yoshida, Yoshihiro Umezawa, Haryoon Kim, Motohiro Kato, Yoshiko Atsuta, Koji Kato   +21 more
wiley   +1 more source

Amyloid‐β aggregates induce vasculopathy via ferroptosis in brain endothelial cells

Brain Pathology, EarlyView.
Blood–brain barrier (BBB) disruption is evident in brains with amyloidopathy. In this study, we demonstrate that amyloid β (Aβ) drives abnormal lipid metabolism and lipid droplet formation in brain endothelial cells, leading to lipid peroxidation and ferroptosis.
Suhyeon Son, Suji Kim, Min‐Tae Jeon, Moonseok Choi, Kyu‐Sung Kim, Suji Lee, Seung‐Yeol Nah, Do‐Geun Kim   +7 more
wiley   +1 more source