Results 201 to 210 of about 115,871 (339)

Differential cell death decisions in the testis: evidence for an exclusive window of ferroptosis in round spermatids [PDF]

, 2019
Elizabeth G. Bromfield, Jessica L. H. Walters, Shenae L. Cafe, Ilana R. Bernstein, Simone J. Stanger, Amanda L. Anderson, R. John Aitken, Eileen A. McLaughlin, Matthew D. Dun, B.M. Gadella, Brett Nixon   +10 more
openalex   +1 more source

The Regulation of Ferroptosis by Tumor Suppressor p53 and its Pathway [PDF]

, 2020
Juan Liu, Cen Zhang, Jianming Wang, Wenwei Hu, Zhaohui Feng   +4 more
openalex   +1 more source

Tumor Intrinsic METTL5 Modulates ATF4 Translation to Prevent T Cell‐Induced Ferroptosis in Ovarian Cancer

Advanced Science, EarlyView.
An integrative analysis combining in vitro genome‐wide immune screens, in vivo ICB screens, and clinical data mining identifies METTL5 as a key tumor‐intrinsic immune factor. Mechanistic studies further reveal the importance of the METTL5‐ATF4‐SLC7A11/SLC3A2‐ferroptosis axis in modulating antitumor immune responses. These findings highlight METTL5 as a
Jiakai Hou, Cheng‐Wei Ju, Nicholas A. Egan, Yanjun Wei, Yunfei Wang, Minghao Dang, Tianyi Zhou, Leilei Shi, Ningbo Zheng, Si Chen, Ashley M. Guerrero, Xiaofang Liang, Wanfu Wu, Areej Akhtar, Chitra Dhiman, Debanwita Roy Burman, Andro E. Gerges, Mason D. Flores, Han Li, Li‐Sheng Zhang, Marleen Kok, Xiaobo Mao, Linghua Wang, Qin Feng, Yiwen Chen, Sanghoon Lee, Daniel J. McGrail, Nidhi Sahni, Chuan He, Amir A. Jazaeri, Weiyi Peng   +30 more
wiley   +1 more source

Cigarette smoking is associated with high level of ferroptosis in seminal plasma and affects semen quality [PDF]

, 2020
Zhanhui Ou, Qirong Wen, Yu Deng, Yang Yu, Zhiheng Chen, Ling Sun   +5 more
openalex   +3 more sources

Ferroptosis is newly characterized form of neuronal cell death in response to arsenite exposure

, 2018
Qianghu Tang, Lulu Bai, Zhen Zou, Meng Pan, Yinyin Xia, Shuqun Cheng, Shaoyu Mu, Jianrong Zhou, Xuefeng Wang, Xia Qin, Xianqing Cao, Xuejun Jiang, Chengzhi Chen   +12 more
openalex   +2 more sources

Concurrent Mutations in STK11 and KEAP1 Promote Ferroptosis Protection and SCD1 Dependence in Lung Cancer [PDF]

, 2020
Corrin A. Wohlhieter, Allison L. Richards, Fathema Uddin, Christopher H. Hulton, Àlvaro Quintanal-Villalonga, Axel Martin, Elisa de Stanchina, Umesh Bhanot, Marina Asher, Nisargbhai Shah, Omar Hayatt, Darren J. Buonocore, Natasha Rekhtman, Ronglai Shen, Kathryn C. Arbour, Mark T.A. Donoghue, John T. Poirier, Triparna Sen, Charles M. Rudin   +18 more
openalex   +1 more source

ACS Chem Biol [PDF]

While opto-genetics has proven to have tremendous value in revealing the functions of the macromolecular machinery in cells, it is not amenable to exploration of small molecules such as phospholipids (PLs).

core  

Engineering Bacteria as Living Therapeutics in Cancer Therapy

Advanced Science, EarlyView.
Through synthetic biology approaches, natural bacteria can be genetically programmed into multifunctional living therapeutics. These engineered bacteria are capable of secreting anti‐tumor factors, displaying tumor‐associated antigens on their surface, or undergoing programmed self‐lysis to release therapeutic cargo.
Jiangfeng Chen, Jiaqi Chen, Yixuan Chen, Wenxuan Yuan, Jiao Zhang, Guoqing Wang, Zhuojun Dai   +6 more
wiley   +1 more source

miR-182-5p and miR-378a-3p regulate ferroptosis in I/R-induced renal injury [PDF]

, 2020
Chenguang Ding, Xiaoming Ding, Jin Zheng, Bo Wang, Li Yang, Heli Xiang, Meng Dou, Yuxi Qiao, Puxun Tian, Wujun Xue   +9 more
openalex   +1 more source

Tumor‐Targeted FABP5/STING Cascade Promote Radiofrequency Ablation Induced Ferroptosis and Intratumoral Immune Rewiring in Hepatocellular Carcinoma

Advanced Science, EarlyView.
Targeted FABP5 co‐delivery nanoparticles amplify RFA‐induced ferroptosis and intratumoral immune rewiring via STING/TBK1 pathway activation in HCC. The pH‐responsive lipid nanoshell was integrated with cyclic RGD peptide (cRGD) and red blood cell membrane (RBCM), and encapsulated with superparamagnetic iron oxide (SPIO) and sgFABP5 to construct FS@RBCM/
Bufu Tang, Xiaojie Zhang, Yiting Sun, Jinhua Luo, Qiaoyou Weng, Cong Zhang, Zilin Wang, Shiji Fang, Yangrui Xiao, Liyun Zheng, Jianfei Tu, Rongfang Qiu, Yang Yang, Zhongwei Zhao, Weiqian Chen, Minjiang Chen, Jiansong Ji   +16 more
wiley   +1 more source