Results 221 to 230 of about 90,650 (265)

The Metabolic Underpinnings of Ferroptosis

open access: yesCell Metabolism, 2020
Acute or chronic cellular stress resulting from aberrant metabolic and biochemical processes may trigger a pervasive non-apoptotic form of cell death, generally known as ferroptosis. Ferroptosis is unique among the different cell death modalities, as it has been mostly linked to pathophysiological conditions and because several metabolic pathways, such
Jiashuo Zheng, Marcus Conrad
exaly   +4 more sources

Role of Ferroptosis in Stroke

Cellular and Molecular Neurobiology, 2022
Stroke is a common and serious nervous system disease caused by the rupture or blockage of the cardiovascular system. It causes millions of deaths and disabilities every year, which is a huge burden on humanity. It may be induced by thrombosis, hypertension, hyperlipidemia, hyperglycemia, smoking, advanced age and so on.
Yunfei Xu   +5 more
openaire   +2 more sources

Ferroptosis

Encuentros en la Biología, 2022
La ferroptosis es una muerte celular programada, oxidativa y dependiente de hierro que ha sido recientemente descrita. A pesar del poco tiempo en el que se lleva estudiando, se han hecho grandes hallazgos sobre su regulación y sus implicaciones fisiopatológicas tanto en cáncer como en procesos inflamatorios.
openaire   +2 more sources

Ferroptosis in Neurological Disease

The Neuroscientist, 2022
Iron accumulation in the CNS occurs in many neurological disorders. It can contribute to neuropathology as iron is a redox-active metal that can generate free radicals. The reasons for the iron buildup in these conditions are varied and depend on which aspects of iron influx, efflux, or sequestration that help maintain iron homeostasis are dysregulated.
Samuel David   +3 more
openaire   +2 more sources

Ferroptosis and Cancer Immunotherapy

Current Molecular Medicine, 2023
Abstract: Traditional treatment strategies for cancer are unsatisfactory. As a nonapoptotic cell death process and owning to the characteristics of iron-dependent lipid peroxide accumulation, ferroptosis has become a new target of tumor treatment. Numerous studies have proved that ferroptosis could enhance the immunogenicity of cancer and interact ...
Jumei, Yin   +6 more
openaire   +2 more sources

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