Results 251 to 260 of about 138,617 (359)

GLS1 Orchestrates Exosome‐Mediated Tumor‐Endothelial Communication to Facilitate Angiogenesis

Advanced Science, EarlyView.
This study reveals a previously unappreciated, non‐metabolic function of GLS1 in the control of tumor angiogenesis via exosome‐mediated CAV1‐TNC signaling, indicating that therapeutic targeting of GLS1 may offer a dual benefit by simultaneously suppressing tumor metabolic activity and angiogenic processes in head and neck cancer. ABSTRACT Glutaminase 1
Jianqiang Yang, Zhenzhen Fu, Fanghui Chen, Soumya Vijaya Kumar, Fan Yang, Yaochao Zheng, Yunqi Li, Yao Yao, Nabil F. Saba, Yong Teng   +9 more
wiley   +1 more source

The Crosstalk Mechanisms Between Ferroptosis and Pyroptosis and Their Applications in Diseases: From Molecular Networks to Clinical Strategies. [PDF]

J Cell Mol Med
Zhao WY, Li LY, Ye FW, Zhao JW.
europepmc   +1 more source

Dual‐Stage Microneedle Patch With Lipid Droplet‐Mediated ‘Capture‐Kill’ and Sustained Release for Enhanced Wound Healing

Advanced Science, EarlyView.
We report a lipid‐droplet‐engineered, gallium‐loaded sonodynamic therapeutic platform (LDTG) incorporated into a bilayer microneedle (MN) patch co‐delivering all‐trans retinoic acid (ATRA), termed LDTG A‐MNs, for synergistic antibacterial therapy and accelerated wound repair.
Peng Jiang, Meijun Jiang, Jiapeng Lei, Wen Zhang, Huiyuan Yang, Xueyang Wang, Siyu Zhang, Qiongfang Ruan, Shuhua Liu, Wei Li   +9 more
wiley   +1 more source

Electroacupuncture ameliorates ulcerative colitis by suppressing ferroptosis via the JAK2/STAT3 signaling pathway

Tao Zhu, Hong-ye Wan, Zhengyang Qu, Hongkai Zhu, Laixi Ji, Jing Zhang   +5 more
openalex   +1 more source

Regulation of fatty acid oxidation involved in high altitude hypoxia induced cardiomyocyte ferroptosis via the SIRT1-PPARα-GPX4 signaling pathway [PDF]

Xiaona Song, Jie Chen, Hongbao Xu, Ling Zhang, Zirou Wang, Lingling Pu, Zhaoli Chen, Xinxing Wang, Weili Liu   +8 more
openalex   +1 more source

Predominance of Ferroptotic Cell Death Mechanisms in Substantia Nigra Neurodegeneration in Parkinson's Disease

Annals of Neurology, EarlyView.
Objective The extent of neuronal loss in Parkinson's disease (PD) and the pathogenic processes underlying neuronal dysfunction and loss remain poorly understood. Here, we analyzed the expression of key molecules representing different cell death signaling pathways and their association with Lewy pathology, dopaminergic (DA) neuron loss and stage of PD ...
Yue Jing Heng, Anusha Jayaraman, Richard Reynolds, Jia Nee Foo   +3 more
wiley   +1 more source

Crosstalk between autophagy and ferroptosis in liver diseases (Review). [PDF]

Int J Mol Med
Wei Y, Zhou K, Su Y, Luan Z, Li P, Chang Y, Han B, Li H, Qiao Y, Ren J.   +9 more
europepmc   +1 more source

Identification of FADS2 as a Contributor of Ferroptosis Escape in Bladder Cancer

Pei-Xin Li, Shengwen Yao, Wenqiang Qi, Hanwen Liu, Xiaoyi Zhang, Bin Zhou, Shijie Zhang, Yao-Zhong Zhang, Hao Liang, Huangwei Huang, Yihao Zhao, Benkang Shi, Jun Chen, Jingchao Liu   +13 more
openalex   +1 more source

Bergamottin pretreatment attenuates cisplatin-induced acute kidney injury in mice by inhibiting BACE-1-mediated ferroptosis. [PDF]

Ren Fail
Yang XP, Wang YJ, Xu YS, Peng S, Yuan HF.   +4 more
europepmc   +1 more source

Hepatocellular carcinoma's inflammatory secret: ferroptosis as the key. [PDF]

Transl Cancer Res
Caro AA, LoBianco FV, Aykin-Burns N.
europepmc   +1 more source