Results 231 to 240 of about 89,109 (264)
Some of the next articles are maybe not open access.
Ferroptosis and Cancer Immunotherapy
Current Molecular Medicine, 2023Abstract: Traditional treatment strategies for cancer are unsatisfactory. As a nonapoptotic cell death process and owning to the characteristics of iron-dependent lipid peroxide accumulation, ferroptosis has become a new target of tumor treatment. Numerous studies have proved that ferroptosis could enhance the immunogenicity of cancer and interact ...
Jumei, Yin +6 more
openaire +2 more sources
The chemical basis of ferroptosis
Nature Chemical Biology, 2019Lipid peroxidation underlies the mechanism of oxidative cell death now known as ferroptosis. This modality, distinct from other forms of cell death, has been intensely researched in recent years owing to its relevance in both degenerative disease and cancer.
Marcus Conrad, Derek A. Pratt
openaire +3 more sources
Ferroptosis in Cardiovascular Diseases and Ferroptosis-Related Intervention Approaches
Cardiovascular Drugs and TherapyCardiovascular diseases (CVDs) are major public health problems that threaten the lives and health of individuals. The article has reviewed recent progresses about ferroptosis and ferroptosis-related intervention approaches for the treatment of CVDs and provided more references and strategies for targeting ferroptosis to prevent and treat CVDs.A ...
Xianpeng, Zhou +9 more
openaire +2 more sources
The Journal of Biochemistry
Abstract Ferroptosis is a form of regulated cell death characterized by iron-dependent phospholipid peroxidation and is closely related to various diseases. System Xc−, a cystine/glutamate antiporter, and glutathione peroxidase 4 (GPX4) are key molecules in ferroptosis.
openaire +2 more sources
Abstract Ferroptosis is a form of regulated cell death characterized by iron-dependent phospholipid peroxidation and is closely related to various diseases. System Xc−, a cystine/glutamate antiporter, and glutathione peroxidase 4 (GPX4) are key molecules in ferroptosis.
openaire +2 more sources
Ferroptosis in mitochondrial cardiomyopathy
Trends in Cell BiologyFerroptosis is a form of necrotic cell death characterized by iron-dependent lipid peroxidation culminating in membrane rupture. Accumulating evidence links ferroptosis to multiple cardiac diseases and identifies mitochondria as important regulators of ferroptosis.
Ahola, S., Langer, T.
openaire +4 more sources
Sweet signaling for ferroptosis
Cell Chemical BiologyA recent study published in Nature Cell Biology by Zhang et al. has uncovered a critical role for O-GlcNAcylation in sensing and regulating ferroptosis.1 Ferroptosis-induced ROS promotes OGT-mediated FOXK2 O-GlcNAcylation, driving its nuclear translocation to upregulate SLC7A11 and suppress cell death.
Fan, Yu, Lingyu, Jiang, Quan, Chen
openaire +2 more sources
Ferroptosis: A Frontier in Osteoporosis
Hormone and Metabolic ResearchAbstractReduced bone mass and degeneration of the microarchitecture of bone tissue are the hallmarks of osteoporosis, a bone metabolic disease that increases skeletal fragility and fracture susceptibility. Osteoporosis is primarily caused by unbalanced bone remodeling, in which bone synthesis ...
Shubhrat, Maheshwari +2 more
openaire +2 more sources
Ferroptosis surveillance independent of GPX4 and differentially regulated by sex hormones
Cell, 2023Deguang Liang +2 more
exaly