Results 251 to 260 of about 155,094 (383)

Features of experimental modeling of ferroptosis of hepatocytes

, 2022
V. S. Ponamarev
openalex   +2 more sources

Qing-Chang-Hua-Shi granule ameliorates experimental colitis by modulating Lactobacillus gasseri-mediated ferroptosis metabolic pathway. [PDF]

Chin Med
Cheng C, Zhu L, Hu J, Feng W, Li W, Au R, Li Y, Xu F, Wu Y, Cui Y, Di Z, Li B, Miao Y, Lin Y, Ge L, Shen H.   +15 more
europepmc   +1 more source

USP35 Acts as a Deubiquitinating Enzyme for ID3 to Promote Immune Escape in Colorectal Cancer

Advanced Science, EarlyView.
USP35 stabilizes ID3 expression by deubiquitinating the K2/K30 site, thereby upregulating PD‐L1 and promoting immune escape in colorectal cancer. IU1, an inhibitor of USP35 enzyme activity, has been shown to inhibit USP35, thereby accelerating ID3 degradation, enhancing CD8+ T cell killing, and reversing the immunosuppressive microenvironment ...
Wenxin Chen, Ling Wang, Hongmei Fan, Lisheng Li, Lingyu Zhang, Ruoxin Li, Fang Liu, Fuli Wen, Yunbin Ye, Chuanzhong Huang   +9 more
wiley   +1 more source

Identification of essential sites of lipid peroxidation in ferroptosis

Nature Chemical Biology, 2023
A. N. von Krusenstiern, R. Robson, Naixin Qian, Baiyu Qiu, Fanghao Hu, Eduard Reznik, N. Smith, Fereshteh Zandkarimi, Verna M. Estes, Marcel M. Dupont, Tal Hirschhorn, M. Shchepinov, Wei Min, K. Woerpel, B. Stockwell   +14 more
semanticscholar   +1 more source

Ferroptosis-immune-metabolic axis in asthma: mechanistic crosstalk, endotype-specific regulation, and translational targeting. [PDF]

Front Immunol
Ni FX, Hu J, Chen PS, Chen HH, Huang DH, Jiang ZB.   +5 more
europepmc   +1 more source

Tobacco Smoke Exposure From Prenatal To Adolescent Periods Drives IBD Pathogenesis: Dynamic DNA Methylation Signatures Across Lifespan Stages

Advanced Science, EarlyView.
This study illustrates that maternal smoking during pregnancy (MSDP) is an independent risk factor for IBD in offspring, and DNA methylation serves as a key mechanistic pathway connecting early‐life smoking exposure with IBD risk in offspring. That highlights the urgent need for preventive interventions targeting prospective parents and minors to ...
Han Zhang, Jianhui Zhao, Jie Chen, Xinyi Ma, Siyun Zhou, Alexandra Noble, Rahul Kalla, Judith Wellens, Kun Liu, Evropi Theodoratou, Jack Satsangi, Xue Li   +11 more
wiley   +1 more source

Conversion of Transplanted Mature Hepatocytes into Afp+ Reprogrammed Cells for Liver Regeneration After Injury

Advanced Science, EarlyView.
Donor‐derived tdTomato+ mature hepatocytes were FACS‐isolated and transplanted into Fah−/− host mice. During regeneration, these cells convert into proliferative, unipotent Afp+ rHeps. Their plasticity is governed by a PPARγ/AFP‐dependent metabolic switch, segregating into pro‐proliferative Afplow and pro‐survival Afphigh subpopulations.
Ting Fang, Chao Yang, Hua Qiu, Yuan Du, Xicheng Wang, Yuting Li, Mingyang Xu, Changcheng Liu, Xiuhua Li, Na Guo, Jun Shi, Wencheng Zhang, Zhiying He   +12 more
wiley   +1 more source

MED12 Dictates Epithelial Ovarian Cancer Cell Ferroptosis Sensitivity via YAP-TEAD1 Signaling. [PDF]

Int J Mol Sci
Luo X, Ding Y, Wang Z, Liu J.
europepmc   +1 more source

B355252 Targets UCP2 to Rescue Intracerebral Hemorrhage-Induced Injury by Promoting Mitochondrial Fusion and Inhibiting Ferroptosis [PDF]

Bo Hoon Han, Changsheng Ma, Yongping Liu, Chenfeng Shi, Jia Guo, Min Bai, Mengyuan Duan, Shu-Chen Meng, Jiaqi Liu, Maotao He   +9 more
openalex   +1 more source

Glutathione peroxidase 4 as an emerging therapeutic target in osteoarthritis: focus on ferroptosis. [PDF]

Front Cell Dev Biol
Zhang L, Li J, Yang X, Yang L.
europepmc   +1 more source