Results 251 to 260 of about 115,871 (339)

Loss of ACSL1 fuels ferroptosis resistance in clear cell renal carcinoma. [PDF]

open access: yesCancer Biol Ther
Wang S   +13 more
europepmc   +1 more source

Autophagy‐Targeting Fe–Cu Nanozyme for Tumor Immune Microenvironment Remodeling and Image‐Guided Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
In this study, a multifunctional iron‐copper metal–organic framework nanozyme platform co‐delivering chloroquine and perfluorohexane is engineered to circumvent tumor immune evasion by disrupting autophagic flux and restoring major histocompatibility complex class I presentation. This dual‐action nanoplatform orchestrates synergistic autophagy blockade
Li Yan   +8 more
wiley   +1 more source

Su1063 – Mir-4715-3P Modulates Aurka and Induces Ferroptosis in Upper Gastrointestinal Cancers

open access: bronze, 2019
Ahmed R. Gomaa   +5 more
openalex   +1 more source

Acidogenesis‐Propelled Coordination Transition in Light‐Triggered Fe‐Polyphenol Polymer for Reactive Oxygen Species‐Augmented Antitumor Therapy

open access: yesAdvanced Science, EarlyView.
A novel iron‐polyphenol‐photoacid coordination polymer (FeBPs) is designed to achieve red light‐triggered external acidification and internal coordination regulation, where this light‐controlled acidification induces coordination changes that enhance Fe active site exposure and provide H+ for beneficial Fe3+/Fe2+ conversion, thereby accelerating ROS ...
Ying Wan   +7 more
wiley   +1 more source

Illuminating the Unseen and Targeting the Untreatable: Aggregation‐Induced Emission Nanoparticles as Intelligent, Immune‐Compatible Tools for Precision Cancer Theranostics

open access: yesAggregate, EarlyView.
Rationally engineered AIE nanoparticles can unite deep‐tissue imaging, photodynamic therapy, photothermal therapy, and immune microenvironment reprogramming. Through precise photophysical tuning and targeted delivery, these intelligent nanoplatforms enable real‐time monitoring, potent tumor eradication, and immune activation, offering a versatile and ...
Quazi T. H. Shubhra   +5 more
wiley   +1 more source

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