Results 261 to 270 of about 115,871 (339)

Iron-responsive-like elements and neurodegenerative ferroptosis

, 2020
Jack T. Rogers, Catherine M. Cahill
openalex   +1 more source

Natural Polyphenol–Metal Supramolecular Nanocomplex for Ferroptosis Activation in Chemoresistant Hepatocellular Carcinoma

Aggregate, EarlyView.
This study presents a supramolecular nanocomplex assembled from a natural polyphenol and Cu(II) that enables cascade glutathione (GSH) depletion through synthesis inhibition, redox cycling, and Michael addition. The system induces dual cytoplasmic and mitochondrial ferroptosis in cisplatin‐resistant hepatocellular carcinoma (HCC), reverses drug ...
Yan Qin, Jialong Fan, Yi Zhang, Wei Yang, Jianzhong Cao, Bin Liu, Qing He   +6 more
wiley   +1 more source

Natural Compounds as Modulators of Ferroptosis: Mechanistic Insights and Therapeutic Prospects in Breast Cancer. [PDF]

Biomolecules
He H, Yu H, Zhou H, Cui G, Shao M.
europepmc   +1 more source

Vízoldható antioxidánsok döntéshelyzetben [PDF]

, 2018
Szarka, András
core   +1 more source

Nanozymes for Non‐Neoplastic Diseases: Catalytic Therapy Redefined

Aggregate, EarlyView.
Non‐neoplastic diseases pose a significant health burden. Nanozymes, enzyme‐like nanomaterials, offer promising strategies for regulating oxidative stress and inflammation. This review explores their development, structure–function relationships, and therapeutic potential, with a focus on precision medicine through targeted delivery and multimodal ...
Ling Mei, Xikai Wang, Zhuang Hu, Jierui Yan, Xiaobo Wang, Haoran Wang, Ya Hou, Pengfei Zhang, Qihang Ding   +8 more
wiley   +1 more source

Multimodal analysis investigating the shared pathogenic mechanisms of osteoporosis and osteoarthritis with an initial exploration of the role of ferroptosis. [PDF]

PLoS One
Wang C, Ran D, Li W, Yang C, Li W.
europepmc   +1 more source

Regulatory mechanism of ferroptosis, a new mode of cell death

, 2019
Da Liu, Guoya Li, Ang Jia, Yanyan Zhao, Chenxi Cao, Xuekun Xing   +5 more
openalex   +2 more sources

Identification of ferroptosis‐related genes involved in chronic obstructive pulmonary disease based on bioinformatics analysis

Animal Models and Experimental Medicine, EarlyView.
The design of the entire paper. Green part represents the bioinformatics analysis approach. Yellow part represents the ideas of animal experiment. Abstract Background Chronic obstructive pulmonary disease (COPD) is a type of chronic respiratory disease.
Xuejing Luan, Jinghui Xie, Lu Zhang, Xiao Ma, Lichangtian Jiao, Jie Zhu   +5 more
wiley   +1 more source

Natural products targeting ferroptosis in cancer: molecular mechanisms and applications. [PDF]

Front Oncol
Ye X, Ju X.
europepmc   +1 more source

Back Again to the Future: A New Era for Cerebroprotection

Annals of Neurology, EarlyView.
Cerebroprotection is a fresh framework for designing neurological therapy that targets glia and vascular cells, in addition to neurons. In the future, successful cerebroprotection will involve targeting all elements of the neurovascular unit. Preclinical trials must include functional outcomes, as well as lesion morphometry.
Patrick Lyden
wiley   +1 more source