Results 131 to 140 of about 967,634 (337)

Comparative effects of streptozotocin, dehydroepiandrosterone and letrozole with high fat diet on ovarian injury induction and functional impairment

Scientific Reports
This study investigates the mechanisms by which environmental factors affect ovarian function. Environmental toxins and unhealthy lifestyles adversely affect women’s health, primarily impair ovarian function. Environmental toxins and unhealthy lifestyles
Leyi Yu, Qingjie Peng, Cunling Ma, Jiahui Ouyang, Hongru Ma, Shuzhe Fan, Miao Sun, Huiming Ma, Xiaoli Du, Xiangdong Zhu, Guangyong Li, Rui He   +11 more
doaj   +1 more source

Nap1L4a Cooperates with Scl/Klf1 to Recruit H2A.Z in Mediating Interactions Among Cis‐Regulatory Elements and Transcription Required for Primitive Erythropoiesis in Zebrafish

Advanced Science, EarlyView.
Nap1l4a is required in erythropoiesis and hypoxia responses via physical interaction with Klf1 and Scl to recruit the histone variant H2A.Z. This facilitates its associated cis‐regulatory element (CRE) remodeling and the consequent chromatin assembly, and activates the transcription of erythroid lineage‐specific genes.
JiaHao Shi, FuMing Lai, Zheng Shen, XiaoYan Zhang, HanFei Wang, WenYe Liu, YunLong Wang, KuanYu Li, GuoLiang Li, YaPing Fang, Jing‐Xia Liu   +10 more
wiley   +1 more source

Study on Hepatotoxicity of Benzophenone-3 at Environmental Concentration in Postpartum Mice

Toxics
Benzophenone-3 (BP-3), a widely used ultraviolet absorber in various scenarios, exhibits estrogenic toxicity at environmental concentrations—as demonstrated in our prior work.
Huai-Fan Zhai, Ya-Nan Tian, Yu-Xin Sheng, Ya-Jia Pu, Yan-Rong Gao, Jia-Yi Chen, Jia-Di Liu, Jia Ma, Hai-Ming Xu, Peng-Bin Yang, Hong-Mei Li   +10 more
doaj   +1 more source

Survey of Third-Party Parenting Options Associated With Fertility Preservation Available to Patients With Cancer Around the Globe [PDF]

, 2017
Purpose: In the accompanying article, “Analysis of Fertility Preservation Options Available to Patients With Cancer Around the Globe,” we showed that specific fertility preservation services may not be offered at various sites around the world because of
Adiga, Satish Kumar, Almeida-Santos, Teresa, Anazodo, Antoinette, Andersen, Claus Yding, Anderson, Richard A., Antunes, Roberto de A., Arvas, Ayse, Ataman, Lauren M., Azambuja, Ricardo, Azmy, Osama, Beerendonk, Catharina C.M., Bourlon, Maria T., Campos-Junior, Paulo Henrique Almeida, Chehin, Maurício Barbour, de Roo, Saskia F., De Vos, Michel, del Mar Andrés, María, Diaz-Garcia, Cesar, Edmonds, Maxwell E., Fathi, Rouhollah, Ferreira Melo e Silva, Lígia Helena, Fontoura, Paula, Furui, Tatsuro, Greenblatt, Ellen M., Grieco, Silvana Chedid, Horbaczewska, Anna, Jach, Robert, Jayasinghe, Yasmin, Khrouf, Mohamed, Kim, Seok Hyun, Lee, Jung Ryeol, Mallmann, Peter, Marcos de Meneses e Silva, Joao, Marinho, Ricardo M., Medrano, Jose, Melo, Cláudia, Mitchell, Rod, Motta, Eduardo, Nelen, Willianne, Ramalho de Carvalho, Bruno, Rashedi, Alexandra S., Reis, Fernando M., Rodrigues, Jhenifer K., Romero, Sergio, Salama, Mahmoud, Sartorio, Cassio, Scarella, Anibal, Shaulov, Talya, Silva, Adelino Amaral, Smith, Kristin, Smitz, Johan, Sugishita, Yodo, Suh, Chang Suk, Suzuki, Nao, Sánchez, Flor, Takae, Seido, Terrado, Guillermo, Van Moer, Ellen, Vega, Mario, Wildt, Ludwig, Winkler-Crepaz, Katharina, Woodruff, Teresa K., Zand, Elnaz   +62 more
core   +3 more sources

HMGB2–RAD21 Axis Promotes Fibro/Adipogenic Progenitor Proliferation and Regulates Fat Infiltration

Advanced Science, EarlyView.
This study constructed the first developmental atlas of embryonic skeletal muscle fibro/adipogenic progenitors (FAPs) and identified an HMGB2+ FAPs subpopulation that regulates FAP pool size and muscle homeostasis. HMGB2 directly targets the RAD21 promoter, and its knockout significantly reduces FAP numbers, thereby lowering the potential for ...
Xian Tong, Ziyun Liang, Tianqi Duo, Liping Pan, Qi Zhu, Jiete Liang, Xianyao Luo, Qingcai Feng, Rong Xu, Yihao Liu, Xu Chen, Luxi Chen, Xiaohong Liu, Yaosheng Chen, Delin Mo   +14 more
wiley   +1 more source

Fertility preservation in women—a practical guide to preservation techniques and therapeutic strategies in breast cancer, Hodgkin's lymphoma and borderline ovarian tumours by the fertility preservation network FertiPROTEKT [PDF]

, 2018
Purpose: Fertility preservation methods are playing an increasing role in women up to the age of 40years because of rising survival rates in those affected by cancer.
Denschlag, Dominik, Dittrich, Ralf, Lawrenz, Barbara, Montag, Markus, Nawroth, Frank, von Wolff, Michael   +5 more
core  

Principles for Rigorous Design and Application of Synthetic Microbial Communities

Advanced Science, EarlyView.
SynComs are artificially designed to enable inter‐species metabolic interactions, metabolic division of labor, and ecological interactions that can elicit phenotypes like colonization stability and environmental adaptation. This systematic review explores the processes used to construct SynComs, the assessment of the mechanisms of metabolic interaction
Yuxiao Zhang, Minyu Jing, Lihui Lyu, Li Nie, Xihui Xu, Ru Sun, Xiyuan Xu, Siyu Chen, Shuobing He, Yumeng Zhang, Ping Huang, Weijie Luo, Jiaojiao Liang, Guifeng Gao, Kunkun Fan, Teng Yang, Liyan Zhang, Xiao Fu, Sarah M. Allard, Jack A. Gilbert, Jiabao Zhang, Haiyan Chu   +21 more
wiley   +1 more source

Magnetic and Crystal Symmetry Control on Spin Hall Conductivity in Altermagnets

Advanced Science, EarlyView.
Crystal structures and schematic illustrations of the spin Hall effect (SHE) in altermagnets. High‐symmetry RuO2 exhibits conventional SHE, while tilted RuO2 shows trivial unconventional SHE (USHE) caused by structural tilting. CrSb and MnTe, with reduced magnetic symmetry, display intrinsic USHE arising from symmetry‐driven spin–momentum locking ...
Dameul Jeong, Seoung‐Hun Kang, Young‐Kyun Kwon   +2 more
wiley   +1 more source

Mapping the Non‐Canonical Splicing Variants: Decrypting the Hidden Genetic Architecture of Idiopathic Male Infertility

Advanced Science, EarlyView.
This study highlights the significance of non‐canonical splicing variants in male infertility, a factor often overlooked during the analysis of high‐throughput sequencing data. Incorporating the non‐canonical splicing variants prioritization in the genetic analysis pipeline will increase the genetic diagnosis of patients with male infertility ...
Kuokuo Li, Yuge Chen, Dongdong Tang, Yuying Sheng, Xu Han, Hao Geng, Na Zhang, Zongliu Duan, Guanxiong Wang, Yang Gao, Rui Guo, Rong Hua, Zhiming Ding, Chuan Xu, Qunshan Shen, Zhen Yu, Bing Song, Mingrong Lv, Yuping Xu, Huan Wu, Ji Wu, Yunxia Cao, Xiaojin He   +22 more
wiley   +1 more source

MR‐DELTAnet: A Longitudinal MRI‐Transformer Model Predicting Pathological Complete Response and Revealing Immune Microenvironment via scRNA‐seq in Locally Advanced Rectal Cancer

Advanced Science, EarlyView.
The MR‐DELTAnet model utilizes longitudinal MRI to predict treatment response after neoadjuvant chemoradiotherapy in locally rectal cancer patients, accurately identifying patients likely to achieve pathological complete response for personalized management.
Wuteng Cao, Huaxian Chen, Jiao Li, Yihui Zheng, Liqing Xie, Guozhong Xiao, Zeyan Wang, Fen Yuan, Junhong Chen, Chongbao Sun, Jing Dai, Jinping Zeng, Xinhua Wang, Lei Wu, Hongcheng Lin   +14 more
wiley   +1 more source