Results 131 to 140 of about 37,352 (297)

A multifaceted microenvironment nanoregulator for targeted ovarian cancer therapy

Frontiers in Pharmacology
The treatment of ovarian cancer is hindered by its insidious onset and rapid progression. Exosomes (EXOs) present a promising therapeutic strategy for ovarian cancer by modulating the tumor microenvironment.
Yizheng Zu, Yizheng Zu, Min Li, Min Li, Ruyue Li, Ruyue Li, Shaohan Ma, Shaohan Ma, Yu’e Yang, Yu’e Yang, Shun Zhang, Yuan Ma, Yuan Ma, Tiantian Wu, Chunfang Ha, Chunfang Ha   +15 more
doaj   +1 more source

Fertility preservation Update [PDF]

, 2012
Several options are currently available for the preservation of fertility: embryo cryopreservation, oocyte cryopreservation, and ovarian tissue cryopreservation.
Dolmans, Marie-Madeleine, Donnez, Jacques, Jadoul, Pascale   +2 more
core  

Ursolic Acid Alleviates Orchitis via Modulating Ferroptosis in Peritubular Myoid Cells of Testis

Animal Research and One Health, EarlyView.
Ursolic acid modulates key ferroptosis‐related pathways in the peritubular myoid cells of the testis in forest musk deer. ABSTRACT Chronic stress adversely affects reproductive health, increasing susceptibility to pathologies such as orchitis. Additionally, the maintenance of iron homeostasis is essential for preserving the function of the testicles ...
Yang Wang, Tianqi Jin, Zexin Chen, Ye Gong, Qimin Liu, Zifang Wu, Heran Cao, Yan Li, Yuyan Liu, Tianhao Yang, Zhihong Jiang, Wuzi Dong   +11 more
wiley   +1 more source

Integration of Nutrition and Organic Agriculture Framework in Managing Gastrointestinal Nematodes in Ruminants

Animal Research and One Health, EarlyView.
Gastrointestinal nematode infections damage the gastrointestinal epithelial tissues of ruminants, affecting nutrient utilization and overall production performance. This review outlines host‐gastrointestinal nematode interactions and discusses integrated control strategies, including nutritional supplementation, grazing management, vaccines, and ...
Wenxun Chen, Xiangfang Tang, Yimin Zhuang, Shengjun Zhao, Ying Ren, Xiaokang Lv   +5 more
wiley   +1 more source

Fertility and fertility preservation techniques for breast cancer patients [PDF]

, 2008
Breast cancer is not rare in younger women. There has been remarkable improvement in the survival rate due to progress in cancer treatment. Those treatments often cause premature ovarian failure due to massive destruction of the ovarian reserve.
Memon, Fouzia
core  

Follicle Stimulating Hormone in Cattle Breeding: Fundamentals, Innovations, and Scope

Animal Research and One Health, EarlyView.
FSH is crucial in cattle reproduction, with exogenous administration enhancing breeding and embryo production. Recombinant FSH offers advantages over pituitary‐extracted variants, including fewer injections, reduced stress, and safer production. These innovations improve breeding efficiency, optimize reproductive outcomes, and contribute to sustainable
Muhammad Shahzad, Hubdar Ali Kolachi, Jesse Oluwaseun Ayantoye, Xiaomeng Zhang, Muhammad Usman Mehmood, Rajilan Hilali Shanga, Pengcheng Wan, Xueming Zhao   +7 more
wiley   +1 more source

Significant Deficits Are Seen in Extensor Muscle Performance but Not Flexor Muscle Performance 6 Months After Anterior Cruciate Ligament Reconstruction Using a Rectus Femoris Tendon Autograft

Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To evaluate bilateral isokinetic performance symmetry of knee extensors and flexors 6 months after anterior cruciate ligament reconstruction using a rectus femoris tendon autograft. Methods This retrospective case series included patients consecutively recruited at a single tertiary sports medicine center between January 2023 and July 2024 ...
Alef Cavalcanti Matias de Barros, Márcio Cabral Fagundes Rêgo, Karinna Sonálya Aires da Costa Oliveira, Marcelo Cabral Fagundes Rêgo, Carlos Eduardo da Silveira Franciozi, Diego Ariel de Lima, Camilo Partezani Helito, José Leonardo Rocha de Faria, Jamilson Simões Brasileiro   +8 more
wiley   +1 more source

Progestin-primed ovarian stimulation for oocyte cryopreservation in patients with nonmedical indications: a case–control study

Reproductive Biology and Endocrinology
Background The PPOS (Progestin Primed Ovarian Stimulation) protocol has been evaluated and has proved its effectiveness in preventing the LH (luteinizing hormone) surge.
Ophélie Sounigo, Léah Cohen Aloro, Michael Grynberg, Céleste Becquart, Maxence Majer, Vincent Puy, Christophe Sifer, Claire Vinolas, Florence Eustache, Laetita Hesters, Anne Mayeur, Isabelle Cedrin-Durnerin, Charlotte Sonigo, Maeliss Peigné   +13 more
doaj   +1 more source

Targeting Amastigote and Trypomastigote Phases: Multi‐Epitope Vaccine Strategy Against Trypanosoma cruzi

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Effective vaccines against Trypanosoma cruzi, the causative agent of Chagas disease, are urgently needed. Here, we report the design and in silico validation of a novel multiepitope vaccine construct targeting the key surface proteins ASP‐2 and gp82. Using a comprehensive immunoinformatics pipeline, we identified and selected 38 potent T‐cell (
Maria Karolaynne da Silva, Caio Patrício de Souza Sena, Davi Serradella Vieira, Magdi E. A. Zaki, Leow Chiuan Yee, Shahina Akter, Umberto Laino Fulco, Jonas Ivan Nobre Oliveira, João Firmino Rodrigues‐Neto   +8 more
wiley   +1 more source

Pregnancy‐related effect on elexacaftor, tezacaftor and ivacaftor pharmacokinetics in women with cystic fibrosis

British Journal of Clinical Pharmacology, EarlyView.
Aim The number of pregnancies among women with cystic fibrosis (wwCF) has steadily increased over the past decade. However, the pharmacokinetics (PK) of elexacaftor–tezacaftor–ivacaftor (ETI) during gestation remains uncharacterized, despite its widespread use in this population.
Paulette Magnas, Naim Bouazza, Frantz Foissac, Saïk Urien, Léo Froelicher‐Bournaud, Gabrielle Lui, Victoria Guillemart, Nicolas Carlier, Jennifer Da Silva, Johanna Fesenbeckh, Reem Kanaan, Isabelle Honoré, Clémence Martin, Jean‐Marc Treluyer, Vassilis Tsatsaris, Pierre‐Régis Burgel, Sihem Benaboud   +16 more
wiley   +1 more source