Results 141 to 150 of about 967,634 (337)

Hidden Charge‐Order in the Mixed‐Valent K0.75Li2Cr6O12 High‐Pressure Oxide

Advanced Science, EarlyView.
K0.75Li2Cr6O12 is one of the few mixed valent chromium oxides. It shows a single angle spiral magnetic structure with a k = [1/3 1/3 ¼] propagation vector. Density functional theory reveals a hidden charge order that is necessary to stabilize the antiferromagnetic (AFM) ground state.
Angel M. Arévalo‐López, Clemens Ritter, Marielle Huvé, Olivier Mentré   +3 more
wiley   +1 more source

Paternal ribosome biogenesis dysfunction caused by cyclophosphamide-busulfan chemotherapy contributes to early embryonic developmental impairment in mice

Journal of Translational Medicine
Background Combined cyclophosphamide (CTX) and busulfan (BUS) chemotherapy, while effective against malignancies, poses significant risks to male reproductive health. This study systematically investigates the proteomic basis underlying CTX + BUS-induced
Xin Li, Zexin Bian, Xialu Liu, Liyun Cao, Peipei Liu, Hongying Xu, Yan Zhao, Jun Tan   +7 more
doaj   +1 more source

A multifaceted microenvironment nanoregulator for targeted ovarian cancer therapy

Frontiers in Pharmacology
The treatment of ovarian cancer is hindered by its insidious onset and rapid progression. Exosomes (EXOs) present a promising therapeutic strategy for ovarian cancer by modulating the tumor microenvironment.
Yizheng Zu, Yizheng Zu, Min Li, Min Li, Ruyue Li, Ruyue Li, Shaohan Ma, Shaohan Ma, Yu’e Yang, Yu’e Yang, Shun Zhang, Yuan Ma, Yuan Ma, Tiantian Wu, Chunfang Ha, Chunfang Ha   +15 more
doaj   +1 more source

Disorders of sex development (DSD): an overview of recent scientific advances [PDF]

, 2014
Developments in biotechnology have radically altered clinical and research themes in the small field of disorders of sex development, as in other rare medical conditions. In the age of genetics, an increasing number of DSDs have been identified. Aided by
Conway, GS
core  

SIRT5–RAC2 Axis Drives Monocyte‐to‐Macrophage Differentiation to Promote Inflammatory Injury in Premature Ovarian Insufficiency

Advanced Science, EarlyView.
SIRT5 desuccinylates and stabilizes RAC2, activating CSF1R‐dependent signaling to drive monocyte differentiation into M0 macrophages and their polarization toward pro‐inflammatory M1 phenotypes in CTX‐induced premature ovarian insufficiency. Inhibiting the SIRT5‐RAC2 axis attenuates inflammation, reduces granulosa cell apoptosis, and preserves ...
Wenjing TanTai, Yaqi Li, Shengnan Liu, Minjuan Wu, Zhixiao Liu, Junfeng Jiang, Jingjing Chen, Xiaoding Xu, Li Li, Chaoqun Li, Fang Zhao, Ye Liu, Haitao Ni, Tengfei Zhang, Mingjuan Xu, Chaofeng Han   +15 more
wiley   +1 more source

Metformin modulates the TXNIP-NLRP3-GSDMD pathway to improve diabetic bladder dysfunction

Scientific Reports
To validate the therapeutic efficacy of metformin on diabetic bladder dysfunction (DBD) and further elucidate whether the TXNIP-NLRP3-GSDMD axis serves as a target for metformin in ameliorating DBD. C57BL/6J mice were induced with diet-induced obesity by
Bincheng Huang, Jin Zhang, Haifu Tian, Shuai Ren, Keming Chen, Jiajin Feng, Shuzhe Fan, Yunshang Tuo, Xuehao Wang, Leyi Yu, Cunling Ma, Qingjie Peng, Xiaojiang Chen, Rui He, Guangyong Li   +14 more
doaj   +1 more source

Desire for children and fertility preservation in transgender and gender-diverse people: A systematic review.

Best Practice & Research: Clinical Obstetrics & Gynaecology, 2023
T. Stolk, J. Asseler, J. Huirne, E. van den Boogaard, N. van Mello   +4 more
semanticscholar   +1 more source

Chemical Doping Engineering of Polarization and Topological Textures in van der Waals Ferroelectric CuInP2S6

Advanced Science, EarlyView.
Our work reports that Li⁺ doping in CuInP2S₆ induces coexistence of high‐ and low‐polarization states, which fosters a rich spectrum of topological polar textures, such as bubbles and labyrinth domains. An unconventional flexoelectric effect is also discovered, where strain gradients can mechanically manipulate these polarization states and their ...
Lei Gao, Wenhao Li, Fei Sun, Ziyi Zhou, Zhihao Shen, Jianwei Liang, He Jiang, Weiming Xiong, Weijin Chen, Xiaoyue Zhang, Yi Zhang, Xinzhi Liu, Yue Zheng   +12 more
wiley   +1 more source

Future potential of IVM including fertility preservation.

Fertility and Sterility, 2023
J. Cadenas, Liv la Cour Poulsen, L. S. Mamsen, C. Y. Andersen   +3 more
semanticscholar   +1 more source

Amphiphilic Polymer Conetworks for Non‐Fullerene Organic Solar Cells: Regulated Molecular Stacking Enables Efficient Downconversion

Advanced Energy Materials, EarlyView.
This work presents a novel bulk‐heterojunction‐integrated organic luminophore geometry using amphiphilic polymer conetworks as an interlayer scaffold. The design enhances optoelectronic performance via efficient downconversion and reinforced molecular stacking, offering a versatile architecture that paves the way for next‐generation organic solar cells.
Chieh‐Szu Huang, Danbi Kim, Wenyan Yang, Yang Lu, Robert J. E. Westbrook, Huagui Lai, Zimu Wei, Chaeyeon Lee, Fan Fu, Neil C. Greenham, Bo Ram Lee, Samuel D. Stranks   +11 more
wiley   +1 more source