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FIGO statement: Fertility preservation

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2023
Fertility preservation is a growing field in reproductive medicine that may raise ethical questions. Preservation of fertility must be discussed with the patient if gonadotoxic treatment is required, whether in the case of benign or malignant pathology ...
L. Henry, Jonathan S. Berek, Ivonne Diaz, D. Feldberg, Edgar Mocanu, C. Niederberger, Samuel Ohlander, Nikhil Purandare, Z. Rosenwaks, T. Tulandi, Megan Wasson, S. Wilailak, Jaideep Malhotra   +12 more
semanticscholar   +1 more source

Fertility Preservation in Young Women With Breast Cancer: A Review

Journal of Breast Cancer, 2023
Fertility preservation is a major concern in young patients diagnosed with breast cancer and planning to receive multimodality treatment, including gonadotoxic chemotherapy with or without age-related decline through long-term endocrine therapy.
Y. Hong, Changhee Park, H. Paik, Kyung-Hun Lee, J. R. Lee, W. Han, Seho Park, Seockhoon Chung, Hee Jeong Kim   +8 more
semanticscholar   +1 more source

[Fertility preservation].

Ugeskrift for laeger, 2021
Fertility preservation should be considered in girls and young women faced with a potentially gonadotoxic treatment such as chemotherapy. IVF can be performed with the aim to collect and freeze the oocytes, or ovarian tissue can be cryopreserved and transplanted back to the patient at a later stage.
Colmorn, Lotte Berdiin, Kristensen, Stine Gry, Dueholm, Margit, Macklon, Kirsten Tryde   +3 more
openaire   +5 more sources

The future of fertility preservation for women treated with chemotherapy

Reproduction and Fertility, 2023
Cytotoxic chemotherapies have been a mainstay of cancer treatment but are associated with numerous systemic adverse effects, including impacts on fertility and endocrine health.
L. Alesi, Q. Nguyen, J. Stringer, A. Winship, Karla J. Hutt   +4 more
semanticscholar   +1 more source

Human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) alleviate excessive autophagy of ovarian granular cells through VEGFA/PI3K/AKT/mTOR pathway in premature ovarian failure rat model

Journal of Ovarian Research, 2023
Background Premature ovarian failure (POF) is one of the leading causes of female infertility and is accompanied by abnormal endocrine, seriously affecting female quality of life.
Wenjie Dai, Hong Yang, Bo Xu, Tiantian He, Ling Liu, Xiaoqian Ma, Jiaxue Ma, Guoqin Yang, Rui Si, Xiuying Pei, Xing Du, Xufeng Fu   +11 more
doaj   +1 more source

Metformin improves polycystic ovary syndrome in mice by inhibiting ovarian ferroptosis

Frontiers in Endocrinology, 2023
Background and objectivePCOS is a common metabolic disorder in women of reproductive age, which pathogenesis is very complex. The role of ferroptosis in PCOS is a novel finding, and the mechanistic studies are not clear. Metformin is a commonly used drug
Qingjie Peng, Xiaojiang Chen, Xiaoxia Liang, Jiahui Ouyang, Qiangqiang Wang, Shuai Ren, Haibo Xie, Chunhong Wang, Yaqun Sun, Xin Wu, Hetao Liu, Changchun Hei, Miao Sun, Qing Chang, Xinrui Liu, Guangyong Li, Guangyong Li, Rui He   +17 more
doaj   +1 more source

High-Survival Rate After Microinjection of Mouse Oocytes and Early Embryos With mRNA by Combining a Tip Pipette and Piezoelectric-Assisted Micromanipulator

Frontiers in Cell and Developmental Biology, 2021
Utilizing microinjection to introduce biological molecules such as DNA, mRNA, siRNA, and proteins into the cell is well established to study oocyte maturation and early embryo development in vitro. However, microinjection is an empirical technology.
Lei-Ning Chen, Lei-Ning Chen, Xiao-Yan Fan, Xiao-Yan Fan, Yi-Tong Liu, Shao-Qing Chen, Feng-Yun Xie, Feng-Yun Xie, Li Zeng, Juan Wen, Jin Li, Jun-Yu Ma, Jun-Yu Ma, Xiang-Hong Ou, Xiang-Hong Ou, Shi-Ming Luo, Shi-Ming Luo, Lei Guo, Lei Guo   +18 more
doaj   +1 more source

Role of antioxidants in fertility preservation of sperm — A narrative review

Animal bioscience, 2022
Male fertility is affected by multiple endogenous stressors, including reactive oxygen species (ROS), which greatly deteriorate the fertility. However, physiological levels of ROS are required by sperm for the proper accomplishment of different cellular ...
A. Qamar, M. I. Naveed, Sanan Raza, Xun Fang, P. Roy, S. Bang, B. Tanga, I. Saadeldin, Sanghoon Lee, Jongki Cho   +9 more
semanticscholar   +1 more source

Fertility Preservation in Girls [PDF]

Obstetrics and Gynecology International, 2012
Children that undergo treatment for cancer are at risk of suffering from subfertility or hormonal dysfunction due to the detrimental effects of radiotherapy and chemotherapeutic agents on the gonads. Cryopreservation of ovarian tissue prior to treatment offers the possibility of restoring gonadal function after resumption of therapy.
Michael Weintraub, Eduardo Mitrani, Ariel Revel, Meital Lebovich, Vardit Ravitsky, Stephen Kennedy, Eitan Gross, Jennia Michaeli, Neri Laufer, Yehuda Ginosar, Einat Eizenman   +10 more
openaire   +3 more sources

For patients with non-obstructive azoospermia, the outcome of testicular sperm extraction correlates with self-esteem, sexual health and the quality of the couple’s relationship

Basic and Clinical Andrology, 2022
Resume Introduction Quelques études concernant l’azoospermie ou les résultats négatifs de l’extraction de sperme testiculaire (TESE) montrent que ces résultats peuvent être liés à la dépression ou aux dysfonctions érectiles.
Marion BENDAYAN, Emine SAIS, Laura ALTER, Khadija FATHALLAH, Monique JAOUL, Pierre Olivier BOSSET, Geoffroy ROBIN, Florence BOITRELLE   +7 more
doaj   +1 more source