Results 111 to 120 of about 282,360 (388)

In Vitro fertilization and adverse obstetric and perinatal outcomes.

open access: yesSeminars in Perinatology, 2017
Most IVF-conceived children are healthy, but IVF has also been associated with adverse obstetric and perinatal outcomes as well as congenital anomalies.
C. Sullivan-Pyke   +3 more
semanticscholar   +1 more source

Effect of cortisol on bovine oocytes maturation and further embryonic development after in vitro fertilization [PDF]

open access: yes, 2018
Dissertação de Mestrado, Engenharia Zootécnica, 07 de dezembro de 2018, Universidade dos Açores.A maturação meiótica dos ovócitos e o posterior desenvolvimento embrionário após a fertilização são importantes requisitos fisiológicos para a sobrevivência ...
Mahdy, Aya Khaled Hassan
core  

RSPO2 Coordinates with GDF9:BMP15 Heterodimers to Promote Granulosa Cell and Oocyte Development in Mice

open access: yesAdvanced Science, EarlyView.
RSPO2 and GDF9:BMP15 heterodimers—core components of oocyte‐secreted factors (OSFs)—coordinate to shape the molecular architecture of preantral granulosa cells via gene‐specific synergistic and antagonistic regulation, mediated through CTNNB1–SMAD2 signaling crosstalk.
Yingmei Wang   +7 more
wiley   +1 more source

A Complementarity‐Based Approach to De Novo Binder Design

open access: yesAdvanced Science, EarlyView.
A novel method for surface complementarity detection (HECTOR) enables highly efficient docking and design of protein interfaces. Applied to therapeutically relevant targets, this method yields de novo binders with potent antagonistic activity. As a first‐principles approach, HECTOR offers a training‐free solution to the binder design problem and is ...
Kateryna Maksymenko   +17 more
wiley   +1 more source

The association between in vitro fertilization outcome and the inflammatory markers of complete blood count among nonobese unexplained infertile couples

open access: yesTaiwanese Journal of Obstetrics & Gynecology, 2018
Objective(s): The purpose of our study was to evaluate whether the inflammatory parameters of complete blood count (CBC), including white blood cell (WBC), neutrophil-to-lymphocyte-ratio (NLR), platelet-to-lymphocyte-ratio (PLR), and mean platelet volume
Esra Nur Tola
doaj  

A Novel Cultivation System for Germ Cell Proliferation and Sustaining Whole Testicular Niche

open access: yesAdvanced Science, EarlyView.
A hydrogel microneedle‐based system enables whole testicular cultivation, supporting spermatogonial proliferation and enhancing spermatogenesis in vitro. This ‘whole testicular spermatogonia pool’ (WTSP) significantly increases spermatid production and fertility potential in mice. This system also promotes spermatogonial expansion in human fetal testes,
Yu Xia   +14 more
wiley   +1 more source

The effect of anesthetic agents for oocyte pick-up on in vitro fertilization outcome: A retrospective study in a tertiary center

open access: yesTaiwanese Journal of Obstetrics & Gynecology, 2019
Objective: General anesthesia is used in most in vitro fertilization (IVF) clinics for oocyte pick-up (OPU), however, there is no consensus on type of anesthetic agent use among clinicians performing OPU.
Esra Nur Tola
doaj  

Live-Birth Rate Associated With Repeat In Vitro Fertilization Treatment Cycles.

open access: yesJournal of the American Medical Association (JAMA), 2015
IMPORTANCE The likelihood of achieving a live birth with repeat in vitro fertilization (IVF) is unclear, yet treatment is commonly limited to 3 or 4 embryo transfers.
Andrew D A C Smith   +3 more
semanticscholar   +1 more source

Effects of simulated weightlessness on meiosis. Fertilization, and early development in mice [PDF]

open access: yes
The initial goal was to construct a clinostat which could support mammalian cell culture. The clinostat was selected as a means by which to simulate microgravity conditions within the laboratory, by constant re-orientation of cells with respect to the ...
Wolgemuth, D. J.
core   +1 more source

Sleep Deprivation Activates a Conserved Lactate‐H3K18la‐RORα Axis Driving Neutrophilic Inflammation Across Species

open access: yesAdvanced Science, EarlyView.
Sleep deprivation triggers systemic immune activation characterized by neutrophil accumulation and cytokine release. This study reveals a conserved metabolic‒epigenetic mechanism whereby lactate‐induced H3K18 lactylation upregulates RORα expression, promoting neutrophilic inflammation.
Ren Zhou   +15 more
wiley   +1 more source

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