Results 121 to 130 of about 2,639,951 (318)

Lineage labeling with zebrafish hand2 Cre and CreERT2 recombinase CRISPR knock‐ins

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background The ability to generate endogenous Cre recombinase drivers using CRISPR‐Cas9 knock‐in technology allows lineage tracing, cell type‐specific gene studies, and in vivo validation of inferred developmental trajectories from phenotypic and gene expression analyses. This report describes endogenous zebrafish hand2 Cre and CreERT2 drivers
Zhitao Ming   +14 more
wiley   +1 more source

Not just a carrier: Clinical presentation and management of patients with heterozygous disease‐causing alkaline phosphatase (ALPL) variants identified through expanded carrier screening

open access: yesMolecular Genetics &Genomic Medicine, Volume 11, Issue 1, January 2023., 2023
This work describes our cross‐disciplinary experience identifying and evaluating 12 patients for clinical, biochemical, and familial features of Hypophosphatasia (HPP) from a retrospective database review of expanded carrier screening (ECS) results in our center.
Natalie M. Beck   +9 more
wiley   +1 more source

Frequency of cytomegalovirus in fertile and infertile men, referring to Afzalipour Hospital IVF Research Center, Kerman, IRAN: A case-control study

open access: yesInternational Journal of Reproductive BioMedicine, 2018
Background: Cytomegalovirus (CMV) virus can hide in urinary genital tract cells and affect male infertility disorders. Objective: To evaluate frequency of CMV in the semen samples of men with infertility problems referring to a in vitro fertilization ...
Majid Mohseni   +4 more
doaj  

Molecular anatomy of emerging Xenopus left–right organizer at successive developmental stages

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Vertebrate left–right symmetry breaking is preceded by formation of left–right organizer. In Amphibian, this structure is formed by gastrocoel roof plate, which emerges from superficial suprablastoporal cells. GRP is subdivided into medial area, which generates leftward flow by rotating monocilia and lateral Nodal1 expressing areas,
Natalia Petri   +3 more
wiley   +1 more source

A network of transient domains for breaking symmetry during anterior–posterior axis formation in the porcine embryo

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Breaking radial symmetry for anterior–posterior axis formation is one of the key developmental steps of vertebrate gastrulation and is established through a succession of transient domains defined by morphology or gene expression. Three such domains were interpreted recently in the rabbit to be part of a “three‐anchor‐point model” for axis ...
Ruben Plöger   +2 more
wiley   +1 more source

Single‐cell RNA‐sequencing of retrieved human oocytes and eggs in clinical practice and for human ovarian cell atlasing

open access: yesMolecular Reproduction and Development, Volume 89, Issue 12, Page 597-607, December 2022., 2022
Abstract With the advancement of single‐cell separation techniques and high‐throughput sequencing platforms, single‐cell RNA‐sequencing (scRNA‐seq) has emerged as a vital technology for understanding tissue and organ systems at cellular resolution. Through transcriptional analysis, it is possible to characterize unique or rare cell types, interpret ...
Jordan H. Machlin, Ariella Shikanov
wiley   +1 more source

Women's Status and Fertility: A Novel Perspective on Low Fertility Issue [PDF]

open access: yesarXiv
This model offers a compelling explanation for the observed decline in fertility rates in developed countries, correlating it with the rising economic status of women, and thereby providing valuable insights for policy-making. In summary, through a game theory model, we identify the rising economic status of women as the underlying cause of low ...
arxiv  

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