Results 111 to 120 of about 114,132,762 (308)

Neurotensin stimulates the sperm acrosome reaction and reduces percentages of fertilization in vitro. [PDF]

F S Sci, 2020
Campbell GE, Jones EL, Comizzoli P, Duffy DM.   +3 more
europepmc   +1 more source

NICE: A Two‐Step Non‐Invasive Framework for Embryo cfDNA Read Enrichment and Quality Assessment

Advanced Science, EarlyView.
The non‐invasive NICE framework, built on an ensemble stacking machine learning model, prioritizes embryos by analyzing cell‐free DNA from spent culture medium. By integrating multimodal signals, including genomic and epigenetic profiles, this automated approach standardizes morphological assessment without human bias, paving the way for more precise ...
Xueya Zhou, Shu Ding, Zhenyi Zhang, Qiaoling Shangguan, Jie Qiao, Peijie Zhou, Yidong Chen   +6 more
wiley   +1 more source

Influence of PEG Molecular Weight on Washout Resistance and Deposition Efficiency of Magnetoresponsive Nanoclusters Under Pulsatile Flow for Magnetic Drug Targeting

Pharmaceuticals
Background/Objectives: Magnetic drug targeting (MDT) using polyethene glycol (PEG)-coated magnetoresponsive nanoclusters (MNCs) can localize therapeutics, but washout from high-shear arterial flow limits efficacy.
Sandor I. Bernad, Elena S. Bernad
doaj   +1 more source

Carbohydrate‐Mediated Cellular Uptake of Boronic Acid Hybrids In Cellulo and Insulin‐Deficient Zebrafish: Live Imaging and Application of Multiphoton FLIM

Advanced Science, EarlyView.
Boronic acid‐based fluorescent hybrids have been used as part of a versatile platform for real‐time metabolic bioimaging across cellular and organismal scales. Including glucose‐responsive imaging in living cells and in an insulin‐deficient vertebrate model, this work opens new opportunities for the development of precision diagnostics, metabolic ...
Haobo Ge, John S. Fossey, David Gonzalez Calatayud, Stephen E. Flower, Sabrina Wang, Hanna Aitessaid, Melita Tvardauskaite, Julia Dudzic, Max Jewell, Charareh Pourzand, Stanley W. Botchway, David Gurevich, Tony D. James, Sofia I. Pascu   +13 more
wiley   +1 more source

EFFECTS OF RISK ON OPTIMAL NITROGEN FERTILIZATION DATES IN WINTER WHEAT PRODUCTION AS AFFECTED BY DISEASE AND NITROGEN SOURCE [PDF]

Optimal fertilization dates were found for two nitrogen sources in the presence of two diseases for wheat farmers with different risk preferences. Risk was independent of fertilization date.
Roberts, Roland K., English, Burton C., Larson, James A., Howard, Donald D., Walters, Jeremy T.   +4 more
core  

Evaluation of different factors affecting the efficiency of oocytes cryopreservation in the bovine model [PDF]

, 2011
Interest in oocyte cryopreservation has recently increased. Cattle oocytes are sensitive to low temperatures, and despite the efforts of numerous research groups cryopreservation of oocytes remains a difficult task.
De Blasi, Marina
core   +1 more source

Magnetic Drug Targeting Under Pulsatile Flow: A Safety-Constrained Framework for Deposition and Retention Stability

Magnetochemistry
Magnetic drug targeting (MDT) is commonly evaluated by peak accumulation at the target site. Under pulsatile flow, however, initial deposition does not predict sustained localisation.
Sandor I. Bernad, Elena S. Bernad
doaj   +1 more source

TGFBI Maintains Fibrocartilage Homeostasis by Restraining O‐GlcNAcylation to Inactivate and Destabilize ADAMTS16 in Temporomandibular Joint Osteoarthritis

Advanced Science, EarlyView.
TGFBI deficiency elevates O‐GlcNAcylation, promoting the transcriptional activation of ADAMTS16 and OGT‐mediated post‐translational modification of ADAMTS16 at Ser1170. This leads to its stabilization and accumulation, driving chondrocyte metabolic disorders and senescent phenotypes, ultimately resulting in fibrocartilage dysfunction and TMJOA ...
Xin Liu, Xinyue Luo, Jie Zhao, Ziyan Jiang, Jiayi Zhai, Taomin Zhu, Xueke Jia, Xiaohan Ma, Henghua Jiang, Huimin Li, Yaping Feng, Jin Ke, Xing Long   +12 more
wiley   +1 more source

Defragmentation of in-vitro fertilization blastocyst stage embryos leading to rescued blastocyst expansion and clinical pregnancy

, 2023
Embryo fragmentation, or extrusion of cell fragments, is a naturally occurring phenomenon that may be associated with impaired embryo development, failed implantation and decreased pregnancy rates.
Chae-Kim, Jennifer J., Waggener, K., Gavrilova-Jordan, L., NC DOCKS at East Carolina University   +3 more
core  

From Particle Retention to Washout: Helical Bypass Geometry Reorganises Flow in Distal Anastomosis

Computation
Current evaluation of bypass graft performance relies predominantly on wall shear stress metrics, even though thrombosis and atherogenesis are fundamentally governed by particle transport and residence within disturbed flow regions.
Sandor I. Bernad, Elena Silvia Bernad
doaj   +1 more source