Results 61 to 70 of about 2,639,951 (318)

Multivariate prediction of mixed, multilevel, sequential outcomes arising from in vitro fertilisation [PDF]

arXiv, 2020
In vitro fertilization (IVF) comprises a sequence of interventions concerned with the creation and culture of embryos which are then transferred to the patient's uterus. While the clinically important endpoint is birth, the responses to each stage of treatment contain additional information about the reasons for success or failure. As such, the ability
arxiv  

Artesunate Inhibits Neointimal Hyperplasia by Promoting IRF4 Associated Macrophage Polarization

Advanced Science, EarlyView.
This study shows that macrophage interferon regulatory factor 4 (IRF4) improved arterial injury‐induced neointimal hyperplasia by promoting of M2 polarization via up‐regulating krüppel‐like factor 4 (KLF4) in rodent and nonhuman primate models. Notably, artesunate is identified as a potent inducer of IRF4 in macrophages, and proposed as a promising ...
Jinlin Miao, Yule Yong, Zhaohui Zheng, Kui Zhang, Wei Li, Jiayi Liu, Siyi Zhou, Juan‐juan Qin, Haoyang Sun, Yatao Wang, Xianghui Fu, Xing Luo, Siyu Chen, Zhi‐Gang She, Jingjing Cai, Ping Zhu   +15 more
wiley   +1 more source

FERTILIZATION OF BOVINE OOCYTES VITRIFIED PRE- AND POST IN VITRO MATURATION

Folia Medica Indonesiana, 2017
The success rate of fertilization post save frozen oocytes is still very low, because the oocyte has distinctive features, namely the volume ratio and a lower surface to the limited penetration of water and cryoprotectants penetrate cells.
Zakiyatul Faizah, Ninik Darsini, Aucky Hinting   +2 more
doaj   +1 more source

Advancements in Biochar as a Sustainable Adsorbent for Water Pollution Mitigation

Advanced Science, EarlyView.
Biochar, obtained through pyrolysis of organic waste, serves as a sustainable solution for wastewater treatment due to its adaptability and low‐cost nature. This review comprehensively examines recent advancements in biochar production, functional modifications, and applications, highlighting the integration of machine learning and artificial ...
Devika Laishram, Su‐Bin Kim, Seul‐Yi Lee, Soo‐Jin Park   +3 more
wiley   +1 more source

EmbryosFormer: Deformable Transformer and Collaborative Encoding-Decoding for Embryos Stage Development Classification [PDF]

arXiv, 2022
The timing of cell divisions in early embryos during the In-Vitro Fertilization (IVF) process is a key predictor of embryo viability. However, observing cell divisions in Time-Lapse Monitoring (TLM) is a time-consuming process and highly depends on experts.
arxiv  

Neuropeptide Ecdysis‐Triggering Hormone and Its Receptor Mediate the Fecundity Improvement of ‘Candidatus Liberibacter Asiaticus’‐Infected Diaphorina citri Females and CLas Proliferation

Advanced Science, EarlyView.
In CLas‐infected D. citri, CLas lowers 20E levels initially, relieving the suppression of ETH release. The subsequent increase in ETH levels upregulates its receptor DcETHR and activates the JH signaling pathway. The signaling cascade of 20E‐ETH/ETHR‐JH along with miR‐210, targeting DcETHR, boost female fecundity in CLas+ D.
Xiaoge Nian, Bo Wang, Paul Holford, George Andrew Charles Beattie, Shijian Tan, Weiwei Yuan, Yijing Cen, Yurong He, Songdou Zhang   +8 more
wiley   +1 more source

Mutations in OOEP and NLRP5 identified in infertile patients with early embryonic arrest

Human Mutation, Volume 43, Issue 12, Page 1909-1920, December 2022., 2022
Abstract The subcortical maternal complex (SCMC), composed of several maternal‐effect genes, is vital for the development of oocytes and early embryos. Variants of SCMC‐encoding genes (NLRP2, NLRP5, TLE6, PADI6, and KHDC3L, but not OOEP and ZBED3) are associated with human oocyte maturation dysfunction, fertilization failure, and early embryonic arrest.
Xiaomei Tong, Jiamin Jin, Zhanhong Hu, Yingyi Zhang, Heng‐Yu Fan, Yin‐Li Zhang, Songying Zhang   +6 more
wiley   +1 more source

Avaliação da aplicabilidade da técnica de maturação in vitro de oócitos humanos e posterior fertilização Evaluation of the usefulness of the in vitro maturation technique of human oocyte and subsequent fertilization

Revista Brasileira de Ginecologia e Obstetrícia, 2003
OBJETIVO: avaliar a aplicabilidade da técnica de maturação in vitro de oócitos humanos e posterior fertilização. MÉTODOS: estudo prospectivo não randomizado descritivo realizado no período de novembro de 1999 a março de 2001 no qual foram incluídas 15 ...
Maria Clara Magalhães dos Santos Amaral, Maria das Graças Rocha Santana Camargos, Marco Aurélio Fernandes Vieira, Rubens Lene Carvalho Tavares, Claudia Navarro Carvalho Duarte Lemos, Aroldo Fernando Camargos   +5 more
doaj   +1 more source

DPImpute: A Genotype Imputation Framework for Ultra‐Low Coverage Whole‐Genome Sequencing and its Application in Genomic Selection

Advanced Science, EarlyView.
DPImpute is a two‐step pipeline that outperforms existing tools in whole‐genome SNP imputation, particularly under conditions of ultra‐low coverage sequencing, small sample sizes, and limited references. It enables precise imputation for single blastocyst cells, supporting genomic selection at the pre‐implantation stage.
Weigang Zheng, Wenlong Ma, Zhilong Chen, Chao Wang, Tao Sun, Wenjun Dong, Wenjing Zhang, Song Zhang, Zhonglin Tang, Kui Li, Yunxiang Zhao, Yuwen Liu   +11 more
wiley   +1 more source

Germline selection of PTPN11 (HGNC:9644) variants make a major contribution to both Noonan syndrome's high birth rate and the transmission of sporadic cancer variants resulting in fetal abnormality

Human Mutation, Volume 43, Issue 12, Page 2205-2221, December 2022., 2022
Mutation frequency heat map of spontaneous PTPN11 variants show spatial clustering in the testis due to germline selection explaining the high birth incidence of Noonan syndrome. Some somatic PTPN11 cancer mutations are similarly clustered in testis. Abstract Some spontaneous germline gain‐of‐function mutations promote spermatogonial stem cell clonal ...
Jordan Eboreime, Soo‐Kyung Choi, Song‐Ro Yoon, Anastasiia Sadybekov, Vsevolod Katritch, Peter Calabrese, Norman Arnheim   +6 more
wiley   +1 more source