Results 41 to 50 of about 115,104 (317)

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Luteinizing hormone dynamics during progestin-primed ovarian stimulation do not predict follicular output in women with normo-ovarian reserve

Frontiers in Endocrinology
BackgroundProgestin-primed ovarian stimulation (PPOS) has emerged as an effective alternative to conventional pituitary suppression strategies in assisted reproductive technology cycles.
Fazilet Kubra Boynukalin, Meral Gultomruk, Neslihan Sonmez, Peter Humaidan, Mustafa Bahceci, Gurkan Bozdag   +5 more
doaj   +1 more source

Therapeutic effects of Vitex (Vitagnus castus) extract on in vitro maturation and fertilization of oocytes in mice affected by polycystic ovary syndrome [PDF]

Āsīb/shināsī-i Darmāngāhī-i Dāmpizishkī, 2020
Polycystic ovary syndrome results from lack of follicular wall collagen reduction leading to accumulation of follicles and decreased oocyte quality. This study aimed to evaluate the effect of vitex extract on in vitro maturation and fertilization of ...
tohid ghorbani, amir karimi, gholamreza najafi, maghsud besharti, Mouhsen Sharafi   +4 more
doaj   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

The association between in vitro fertilization outcome and the inflammatory markers of complete blood count among nonobese unexplained infertile couples

Taiwanese Journal of Obstetrics & Gynecology, 2018
Objective(s): The purpose of our study was to evaluate whether the inflammatory parameters of complete blood count (CBC), including white blood cell (WBC), neutrophil-to-lymphocyte-ratio (NLR), platelet-to-lymphocyte-ratio (PLR), and mean platelet volume
Esra Nur Tola
doaj   +1 more source

Reducing Obstetric Morbidity in In Vitro Fertilization Pregnancies [PDF]

, 2021
Daniela Diego, Heather S. Hipp
openalex   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

The effect of anesthetic agents for oocyte pick-up on in vitro fertilization outcome: A retrospective study in a tertiary center

Taiwanese Journal of Obstetrics & Gynecology, 2019
Objective: General anesthesia is used in most in vitro fertilization (IVF) clinics for oocyte pick-up (OPU), however, there is no consensus on type of anesthetic agent use among clinicians performing OPU.
Esra Nur Tola
doaj   +1 more source

A Surface‐engineered Microfluidic Device for Antibody‐Mediated Negative Selection of High‐Quality Sperm for Assisted Reproduction

Advanced Functional Materials, EarlyView.
This study reports a microfluidic device with a functionalized surface utilizing a polyoxazoline coating and covalently immobilized gold nanoparticles and anti‐phosphatidylserine antibody. The device efficiently eliminates pre‐apoptotic and apoptotic spermatozoa and yields sperm with substantially improved quality and low DNA damage, offering a simple ...
Soraya Rasi Ghaemi, David J. Sharkey, Nicole O. McPherson, Markos Negash Alemie, Krasimir Vasilev, Sarah A. Robertson   +5 more
wiley   +1 more source

Treatment management algorithm for natural frozen embryo transfer cycles using a real-time ovulation prediction machine learning model

Scientific Reports
Our aim was to develop an AI-based NC-FET Treatment Management Algorithm (NTMA), decision-support system that predicts ovulation in real time to manage and optimize natural frozen embryo transfer cycle (NC-FET) scheduling.
Eden Moran, Ariel Hourvitz, Almog Luz, Nevo Itzhak, Rohi Hourvitz, Michal Youngster, Micha Baum, Ettie Maman   +7 more
doaj   +1 more source