Results 31 to 40 of about 115,104 (317)

Oxidative stress markers in GnRH agonist and antagonist protocols in IVF [PDF]

Journal of Medical Biochemistry, 2017
Background: Our aim was to study the effect of GnRH agonist and antagonist protocols of ovarian stimulation on oxidative stress parameters in serum and the influence of oxidative stress parameters change on the outcome of IVF cycles.
Tulić Lidija, Vidaković Snežana, Tulić Ivan, Ćurčić Marijana, Stojnić Jelena, Jeremić Katarina   +5 more
doaj  

A Strategic Program for Risk Assessment and Intervention to Mitigate Environmental Stressor-Related Adverse Pregnancy Outcomes in the Indian Population

Frontiers in Reproductive Health, 2021
The Problem: Global environmental stressors of human health include, but are not limited to, conflict, migration, war, natural disasters, climate change, pollution, trauma, and pandemics.
Divyanu Jain, Ajay K. Jain, Ajay K. Jain, Gerlinde A. S. Metz, Nina Ballanyi, Abha Sood, Rupert Linder, David M. Olson, David M. Olson   +8 more
doaj   +1 more source

Perinatal Outcomes of Singleton, Twin and Triplet Gestations after Oocyte Donation: A Retrospective, Population-Based Cohort Analysis

Children
Background/Objectives: Although high live birth rates are associated with oocyte donation (OD), these pregnancies are associated with increased obstetric and perinatal risks.
Or Eliner, Roni Rahav Koren, Hila Shalev Ram, Mattan Levi, Einat Haikin Herzberger, Amir Wiser, Netanella Miller   +6 more
doaj   +1 more source

How a woman’s myomectomy saved her father’s life: evidence of fumarate hydratase–deficient uterine leiomyoma and early detection of germline variants in fumarate hydratase

F&S Reports, 2022
Objective: To describe a case of a personal and family history of early uterine leiomyomatosis that revealed a pathogenic variant in the FH gene encoding fumarate hydratase.
Greysha Rivera-Cruz, M.D., Baris Boyraz, M.D., Ph.D., John C. Petrozza, M.D.   +2 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Sexual Function and in Vitro Fertilization

Acta clinica Croatica, 2022
Cilj istraživanja bio je ispitati seksualnost osoba koje liječe neplodnost postupcima izvantjelesne oplodnje. Naglasak istraživanja bio je na seksualnoj disfunkciji, seksualnom zadovoljstvu i povezanim čimbenicima rizika. Podaci su prikupljeni na osnovi validiranog i standardiziranog upitnika. Uzorak je činilo 119 ispitanika koji su liječeni postupcima
Andrej Starc, Sanela Aljija, Tomislav Jukić, Raja Dahmane Gošnak, Ante Rotim, Doroteja Pavan Jukić   +5 more
openaire   +4 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Detection of SARS-CoV-2 by real-time PCR under challenging pre-analytical conditions reveals independence of swab media and cooling chain

Scientific Reports, 2021
With global demand for SARS-CoV-2 testing ever rising, shortages in commercially available viral transport media pose a serious problem for laboratories and health care providers.
Sabrina Summer, Ralf Schmidt, Anna Nele Herdina, Isabella Krickl, Julia Madner, Georg Greiner, Florian J. Mayer, Nicole Perkmann-Nagele, Robert Strassl   +8 more
doaj   +1 more source

Characteristics of Infertility Causes in Patients Undergoing in Vitro Fertilization (IVF)

Obgynia, 2021
Objective: The study was done to determine the characteristics of infertility cause in couples undergoing in-vitro fertilization in in-vitro fertilization clinic Bali Royal Hospital Denpasar on January–December 2019.
Ida Bagus Putra Adnyana, Ida Bagus Rendra Kurniawan Artha Depart, Anton Tanjung, Luthfi Rahman   +3 more
doaj   +1 more source