Results 71 to 80 of about 58,955 (309)

Vivencias de la familia del enfermo mental

CuidArte, 2012
Introducción: Es bien conocido que los enfermos mentales son socialmente estigmatizados, han sido motivo del prejuicio de la misma sociedad, dificultando en mayor medida el papel de su familia, en quienes también recae el rechazo, generando en ellos ...
Betsy Flores Atilano, Susana Salgado Jiménez, Teresa Martínez Martínez, Norma Angélica Santiago De la Cruz   +3 more
doaj   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Quinazoline-2,4(1H,3H)-dione derivatives as new class of CB1 Agonists: A pharmacophore-based virtual screening workflow and Lead discovery [version 1; peer review: 2 approved]

F1000Research
Background The cannabinoid 1 (CB1) receptor is the primary target of Δ9-tetrahydrocannabinol (Δ9-THC), the psychoactive component of cannabis sativa (commonly known as “kif” in Morocco).
Fouad Khalil, Abdellah EL AISSOUQ, MOURAD STITOU, Mohamed Enneiymy, Said El Rhabori, Hicham Zaitan, Abdelkrim Ouammou   +6 more
doaj   +1 more source

Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz, Neha V. Safi, Iliana Pliska‐Bloch, Ulrike W. Kaunzner, Ha Luu, Mert Sisman, Yi Wang, Thanh D. Nguyen, Sandra Hurtado Rúa, Susan A. Gauthier   +9 more
wiley   +1 more source

Quinazoline-2,4(1H,3H)-dione derivatives as new class of CB1 Agonists: A pharmacophore-based virtual screening workflow and drug discovery [version 2; peer review: 2 approved]

F1000Research
Background The cannabinoid 1 (CB1) receptor is the primary target of Δ9-tetrahydrocannabinol (Δ9-THC), the psychoactive component of cannabis sativa (commonly known as “kif” in Morocco).
Fouad Khalil, Abdellah EL AISSOUQ, MOURAD STITOU, Mohamed Enneiymy, Said El Rhabori, Hicham Zaitan, Abdelkrim Ouammou   +6 more
doaj   +1 more source

Terapia ocupacional en el adulto mayor como estrategia para prevenir el deterioro cognitivo

CuidArte, 2015
Hoy en día existe la posibilidad de contar con terapias ocupacionales (TO) en los centros de atención al Adulto Mayor que teóricamente pueden ayudar a prevenir el Deterioro Cognitivo y a permitir que ellos realicen de manera independiente sus actividades
Zurisadai Colunga Orozco, Mariana Reymundo Flores, Maria Viviana Valdes Salinas, Javier Alonso Trujillo   +3 more
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Guía general del análisis de los datos en investigación cualitativa para Enfermería

CuidArte, 2013
El objetivo de este trabajo radicó en estructurar un documento general sobre el análisis de los datos que guíe a los aprendices de la investigación cualitativa en esta operación determinante, la que es difícil de comprender.
Leticia Cuevas Guajardo, Dulce María Guillén Cadena, Guillermina Arenas Montaño, Luisa Bravo Sánchez   +3 more
doaj   +1 more source

Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu, Xiaoning Ren, Cuihua Fan, Chun Li, Lijie Zhang, Zaiqiang Zhang, Shaowu Li, Zhongmeng Lai, Bin Cai, Ying Fu, Yi Lin, Zhibao Zhu   +11 more
wiley   +1 more source

Percepción psicosocial del adolescente en familia homoparental y heteroparental

CuidArte, 2012
Objetivo: Conocer la diferencia entre las experiencias psicosociales del adolescente en familia homoparental y heteroparental. Metodología: Fue un estudio cualitativo de tipo explorativo y corte transversal usando el método fenomenológico para la ...
Norma Ivette Beltrán Lugo, Luz Aurora Bribiesca Villaseñor, Thalía Monserrat Valencia López, Ricardo Tadeo Ortíz Garduño   +3 more
doaj   +1 more source