Results 111 to 120 of about 1,787,060 (299)

Single-cell reconstruction of the early maternal–fetal interface in humans

Nature, 2018
R. Vento-Tormo, M. Efremova, R. Botting, M. Turco, Miquel Vento-Tormo, K. Meyer, Jong-eun Park, Emily Stephenson, K. Polański, Ângela Gonçalves, L. Gardner, S. Holmqvist, J. Henriksson, Angela E. Zou, A. Sharkey, Ben Millar, B. Innes, Laura Wood, A. Wilbrey-Clark, R. Payne, M. Ivarsson, S. Lisgo, A. Filby, D. Rowitch, J. Bulmer, Gavin J. Wright, Michael J. T. Stubbington, M. Haniffa, A. Moffett, S. Teichmann   +29 more
semanticscholar   +1 more source

Establishment and optimization of the two‐step induction system for generating primordial germ cell‐like cells from chicken embryonic stem cells

FEBS Open Bio, EarlyView.
This study optimizes a two‐step induction system to generate PGCLCs from chicken ESCs. The induced cells express germline markers and migrate to gonads in ovo, offering a novel approach for avian genetic resource conservation. Primordial germ cells (PGCs) are the progenitor cells of sperm and eggs.
Zeyu Li, XianShuai Xu, GuangZheng Liu, XiaoQian Lv, JiuZhou Song, HongYan Sun, YingJie Niu, QiSheng Zuo, Wei Han, BiChun Li, Kai Jin   +10 more
wiley   +1 more source

Fetal Anomalies in Obstetric Ultrasound in Enugu, Southeast Nigeria

International Journal of Medicine and Health Development
Background: Fetal anomaly (FA) is a global issue with varying degrees of morbidity and mortality. Objectives: To evaluate the various ultrasound-detected FA and their incidence in our environment and ascertain the maternal age group with the highest ...
Salome N. Ezeofor, Augustine C. Onuh, Chiamaka V. Uzochukwu   +2 more
doaj   +1 more source

The impact of Hnrnpl deficiency on transcriptional patterns of developing muscle cells

FEBS Open Bio, EarlyView.
We performed nanopore whole‐transcriptome sequencing comparing RNA from Hnrnpl‐knockdown versus control C2C12 myoblasts to investigate the contributions of Hnrnpl to muscle development. Our results indicate that Hnrnpl regulates the expression of genes involved with Notch signaling and skeletal muscle, particularly splicing patterns of specific muscle ...
Hannah R. Littel, Mekala Gunasekaran, Audrey L. Daugherty, Natalya M. Wells, Johnnie Turner, Christine C. Bruels, Christina A. Pacak, Isabelle Draper, Peter B. Kang   +8 more
wiley   +1 more source

Fetal and Abortion Rights Under the Maastricht Principles on the Human Rights of Future Generations: A Contradiction

Journal of Legal Studies
On 3 February 2023, the Maastricht Principles on the Human Rights of Future Generations was adopted in Maastricht, Netherlands, by a group of human rights experts.
Aguocha Chinedu Collins
doaj   +1 more source

Developmental switching of messenger RNA expression from the human alpha-globin cluster: fetal/adult pattern of theta-globin gene expression [PDF]

, 1992
Maher Albitar, Alessandra Carè, C Peschle, SA Liebhaber   +3 more
openalex   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Editorial: The developing kidney: Perinatal aspects and relevance throughout life

Frontiers in Pediatrics, 2022
Karel Allegaert, Karel Allegaert, Karel Allegaert, Karel Allegaert, Silvia Iacobelli, Silvia Iacobelli   +5 more
doaj   +1 more source

Consensus definition of fetal growth restriction: a Delphi procedure

Ultrasound in Obstetrics and Gynecology, 2016
S. Gordijn, I. Beune, B. Thilaganathan, A. Papageorghiou, A. Baschat, P. Baker, R. Silver, K. Wynia, W. Ganzevoort   +8 more
semanticscholar   +1 more source