Results 51 to 60 of about 1,507,917 (263)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Amnion cells engineering: A new perspective in fetal membrane healing after intrauterine surgery? [PDF]

, 2006
In this study we aimed to set up an in vitro culture of the rabbit amnion in order to support in vivo fetal membrane healing capacity following fetoscopy.
Julia Henke, Susanne Klotz, Schillinger, Ulrike, Kovacs, Laszlo, Horch, R. E., Horch, Raymund E., Matthias Foehn, Andreas Raith, Ulrike Schillinger, Foehn, Matthias, Laszlo Kovacs, Klotz, Susanne, Raymund E. Horch, Papadopulos, Nikolaos A., Edgar Biemer, Föhn, Matthias, Raith, Andreas, Biemer, Edgar, Henke, Julia, Nikolaos A. Papadopulos, Papadopulos, NA;Klotz, S;Raith, A;Foehn, M;Schillinger, U;Henke, J;Kovacs, L;Horch, RE;Biemer, E, Papadopulos, Nikolaos A.;Klotz, Susanne;Raith, Andreas;Foehn, Matthias;Schillinger, Ulrike;Henke, Julia;Kovacs, Laszlo;Horch, Raymund E.;Biemer, Edgar   +21 more
core   +1 more source

Fetal anomalies in prolonged gestation in Awassi ewe: A case report [PDF]

Iraqi Journal of Veterinary Sciences, 2019
This report was described the observation of five types of congenital anomalies with a Hydramnios Syndrome in prolonged gestational (6 months) three years old awassi ewe bearing an abnormal fetus for first time, ultrasonography revealed signs of ...
U. Naoman, B. Al-Watar, E. Lazim, E. Hussein   +3 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Dilemmas in fetal medicine: premature application of technology or responding to womens choice? [PDF]

, 2006
Copyright @ 2006 The Author.It is argued that innovative health technologies (IHTs) may be changing the roles of both patients and health practitioners, and raising new issues, including ethical, legal and social dilemmas.
Williams, C, Clare Williams
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Zika and Flavivirus Shell Disorder: Virulence and Fetal Morbidity

Biomolecules, 2019
Zika virus (ZIKV) was first discovered in 1947 in Africa. Since then, sporadic ZIKV infections of humans have been reported in Africa and Asia. For a long time, this virus was mostly unnoticed due to its mild symptoms and low fatality rates.
Gerard Kian-Meng Goh, A. Keith Dunker, James A. Foster, Vladimir N. Uversky   +3 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

International standards for early fetal size and pregnancy dating based on ultrasound measurement of crown-rump length in the first trimester of pregnancy. [PDF]

, 2014
OBJECTIVES: There are no international standards for relating fetal crown-rump length (CRL) to gestational age (GA), and most existing charts have considerable methodological limitations.
Villar, J, L J Salomon, J Villar, Victora, C. G., Victora, CG, Noble, J. A., Papageorghiou, A. T., Ismail, L. Cheikh, Cheikh Ismail, L, Noble, JA, Kennedy, S. H., E O Ohuma, Ohuma, Eric, R Pang † †, Jaffer, YA, A T Papageorghiou, Dr A Papageorghiou, Altman, DG, Gravett, M. G., Z A Bhutta, Pang, R., Lambert, Ann, J A Noble, Bhutta, ZA, S H Kennedy, Salomon, L. J., Pang, R, Villar, J., M Carvalho, L Cheikh Ismail, Bertino, E., Carvalho, M., Gravett, MG, Altman, D. G., Purwar, M., Bertino, E, C G Victora ¶, #z A B, Kennedy, Stephen, Y A Jaffer, Carvalho, M, E Bertino, International Fetal and Newborn Growth Consortium for the 21st C, Villar, Jose, § § §#, Barros, FC, J, A Lambert, M Purwar ¶ ¶, Kennedy, SH, Papageorghiou, Aris, D G Altman, Lambert, A., Altman, Doug, Ohuma, E. O., M G Gravett § §, Jaffer, Y. A., Salomon, LJ, Lambert, A, F C Barros § ¶, Purwar, M, Carvalho, Maria, Ohuma, EO, Bhutta, Z. A., Papageorghiou, AT, Barros, F. C., Bertino, Enrico   +66 more
core   +1 more source