Results 91 to 100 of about 17,449 (194)

Spatiotemporal dynamics of β‐arrestin‐mediated Src activation in 5‐HT7 receptor signaling pathway

open access: yesThe FEBS Journal, EarlyView.
GPCRs induce distinct cellular responses via G protein‐ or β‐arrestin‐mediated signaling pathways. This study revealed that β‐arrestin‐biased 5‐HT7R ligand induces slow, sustained Src activation, contrasting with transient G protein‐mediated activation.
Hyunbin Kim   +8 more
wiley   +1 more source

Alcohol use disorder: an Australian perspective on screening, diagnosis, treatment and prevention

open access: yesInternal Medicine Journal, EarlyView.
Abstract Alcohol is one of Australia's most harmful recreational drugs, contributing more to death, disease and economic harm than all illicit drugs combined. Though it accounts for 4.1% of the national disease burden, it remains under‐prioritised in health policy, prevention and treatment.
Andrew J. Palmer   +2 more
wiley   +1 more source

Importance of Fetal Alcohol Spectrum Disorders Prevention and Intervention. [PDF]

open access: yesSubst Use Addctn J
Donaldson T   +5 more
europepmc   +1 more source

Cultivating Nurse Leaders: Integrating Policy Analysis Projects in Doctor of Nursing Practice Programmes

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Aim To present the process of establishing a Doctor of Nursing Practice (DNP) policy analysis project option at one nursing school, offering examples of diverse student and graduate analyses to guide other institutions. Background Nurses are skilled patient advocates, and their advocacy forms a crucial foundation for influencing health policy.
Elizabeth K. Kuzma   +10 more
wiley   +1 more source

Annual Research Review: Early conduct problems – precursors, outcomes, and etiology

open access: yesJournal of Child Psychology and Psychiatry, EarlyView.
During the toddler and preschool period, nearly all children engage in some level of aggression, defiance, stealing, and temper tantrums. While the frequency and intensity of these behaviors tends to decrease across early childhood, a subset of children engage in these conduct problem behaviors at a higher intensity early in life and/or do not desist ...
Luke W. Hyde   +2 more
wiley   +1 more source

Sexual dimorphism in lung transcriptomic adaptations in fetal alcohol spectrum disorders. [PDF]

open access: yesRespir Res
Naik VD   +12 more
europepmc   +1 more source

Continued Involvement: A Scoping Review on Family Members' Needs and Experiences Collaborating With Support Staff for Relatives With Intellectual Disabilities Living Outside the Family Home

open access: yesJournal of Intellectual Disability Research, EarlyView.
ABSTRACT Background Family members' involvement in the care for their relative often continues after their relative has moved out of the family home. However, little is known about the needs of family members when collaborating specifically with support staff caring for their relative.
Frances R. Vereijken   +3 more
wiley   +1 more source

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