Combined Face-Brain Morphology and Associated Neurocognitive Correlates in Fetal Alcohol Spectrum Disorders [PDF]
, 2018 BACKGROUND: Since the 1970s, a range of facial, neurostructural, and neurocognitive adverse effects have been shown to be associated with prenatal alcohol exposure. Typically, these effects are studied individually and not in combination.
CIFASD +12 more
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Advanced Science, EarlyView.In the present study, we have demonstrated that the NUP85‐USP47‐ASK1 signaling pathway may have regulated the progression of liver fibrosis through modulating ERS. Additionally, we have developed a CREKA‐coupled liposome to target delivery of MV, a pharmacological inhibitor of NUP85, to activated HSCs, thereby attenuating liver fibrosis. ABSTRACT Liver
Dashuai Yang +11 more
wiley +1 more source
Older Pregnant Women and Binge Drinking: Increasing the Risk of Fetal Alcohol Spectrum Disorder [PDF]
, 2011 Identifying maternal characteristics that increase the risk of Fetal Alcohol Spectrum Disorders (FASD) is a critical step toward creating targeted pregnancy intervention.
Staff, Editorial
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Printable Conductive Hydrogels for Electrochemical Biosensing and Soft Bioelectronic Interfaces
Advanced Science, EarlyView.Flexible, conductive hydrogels that integrate printability, mechanical tunability, biocompatibility, and electronic performance remain challenging to achieve. Here, we develop 3D‐printable poly(ethylene glycol)–poly(pyrrole)‐ hydrogels with tissue‐like mechanics, high cytocompatibility, and robust electrochemical function.
Lukas Hein +6 more
wiley +1 more source
The Complexity of Sleep Disorders in Children with FASD
Quality in SportIntroduction and Purpose: Fetal alcohol spectrum disorders (FASD) is a group of conditions that can occur after prenatal alcohol exposure. In recent years, it is estimated that about 10% of women consume alcohol during pregnancy.
Laura Więcko +6 more
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Fetal alcohol spectrum disorders: a review of interventions for prevention and management in Indigenous communities [PDF]
This resource sheet provides estimates on the prevalence of fetal alcohol spectrum disorders in the general and Indigenous populations of Australia, and reviews the local and international evidence on the effectiveness of programs that aim to prevent or ...
Closing the Gap Clearinghouse
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Biomechanics of foetal movement. [PDF]
, 2015 © 2015, AO Research Institute. All rights reserved.Foetal movements commence at seven weeks of gestation, with the foetal movement repertoire including twitches, whole body movements, stretches, isolated limb movements, breathing movements, head and neck
Nowlan, NC
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First Generation Proteolysis Targeting Chimeras (PROTACs) for the Treatment of Progeria
Advanced Science, EarlyView.We report the first PROTACs designed to degrade progerin, introducing a novel therapeutic approach for progeria. The best compound, UCM‐18142, significantly reduces progerin levels and improves key disease phenotypes in patient‐derived cells and in the LmnaG609G/G609G mouse model, paving the way for new treatment strategies targeting the root cause of ...
Jon Macicior‐Michelena +5 more
wiley +1 more source
Fetal alcohol spectrum disorders: current issues in awareness, prevention and intervention [PDF]
This paper reviews the research and current policy surrounding prenatal alcohol exposure and fetal alcohol spectrum disorders (FASD). Alcohol use during pregnancy is linked to a spectrum of adverse fetal outcomes.
Sara McLean, Stewart McDougall
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Computational prediction of gene targets for fetal alcohol spectrum disorders [PDF]
, 2010 PhD, Faculty of Health Sciences, University of the Witwatersrand, 2008Fetal alcohol spectrum disorders (FASD) describe the range of disorders that result from in utero alcohol exposure.
Lombard, Zane
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