Results 61 to 70 of about 60,676 (321)

Association between fetal sex and maternal plasma microRNA responses to prenatal alcohol exposure: evidence from a birth outcome-stratified cohort

Biology of Sex Differences, 2020
Most persons with fetal alcohol spectrum disorders (FASDs) remain undiagnosed or are diagnosed in later life. To address the need for earlier diagnosis, we previously assessed miRNAs in the blood plasma of pregnant women who were classified as unexposed ...
Nihal A. Salem, Amanda H. Mahnke, Alan B. Wells, Alexander M. Tseng, Lyubov Yevtushok, Natalya Zymak-Zakutnya, Wladimir Wertlecki, Christina D. Chambers, Rajesh C. Miranda, Collaborative Initiative on Fetal Alcohol Spectrum Disorders (CIFASD)   +9 more
doaj   +1 more source

Putting Families First: How the Opioid Epidemic is Affecting Children and Families, and the Child Welfare Policy Options to Address It [PDF]

, 2019
: Opioids and Child Welfare Across the country, placements in foster care are rising. In 2016, the U.S. Department of Health and Human Services reported that 273,539 children in the U.S. entered foster care.
American Academy of Pediatrics Council on Foster Care, Adoption, and Kinship Care, Greiner, Mary V, Laris, Zach, Waite, Douglas   +3 more
core   +1 more source

CHB‐Induced Immune Zonation Chaos Elicited LXRα‐mediated Lipid Metabolism Disorders in Kupffer Cells to Induce Cancer Stem Cell Formation

Advanced Science, EarlyView.
By profiling the spatiotemporal hepatic landscape of CHB mouse models, the originally peri‐portal localized KCs migrated to the peri‐central in a CXCL9‐CXCR3‐dependent manner, facilitating their interaction with HBV+ hepatocytes. The interaction promoted LMD in KCs through ASGR1‐induced LXRα degradation, which, in turn, induced CSC formation via Stat3 ...
Jingqi Shi, Qingyu Li, Jian Li, Jian Bai, Ji Xi, Qi He, Jianglin Zhou, Xuejun Wang, Xiang Song, Xiaoju Li, Xiangpei Yue, Xiaochang Zhang, Zhen Sun, Jiangbo Li, Wen Yang, Yuke Cui, Wenjie Shu, Liang Guo, Shengqi Wang   +18 more
wiley   +1 more source

Fetal Alcohol Spectrum Disorders: an overview from the glia perspective

Frontiers in Integrative Neuroscience, 2016
Alcohol consumption during pregnancy can produce a variety of central nervous system abnormalities in the offspring resulting in a broad spectrum of cognitive and behavioral impairments that constitute the most severe and long-lasting effects observed in
Clare J. Wilhelm, Clare J. Wilhelm, Marina eGuizzetti, Marina eGuizzetti   +3 more
doaj   +1 more source

Risky drinking patterns are being continued into pregnancy: a prospective cohort study [PDF]

, 2014
Background: Risky patterns of alcohol use prior to pregnancy increase the risk of alcohol-exposed pregnancies and subsequent adverse outcomes. It is important to understand how consumption changes once women become pregnant.
Amy E. Anderson
core   +1 more source

Transplantation of GABAergic Interneuron Progenitors Restores Cortical Circuit Function in an Alzheimer's Disease Mouse Model

Advanced Science, EarlyView.
Transplantation of medial ganglionic eminence (MGE) interneuron progenitors into APP/PS1 cortices restored the slow oscillation characteristic of Alzheimer's disease. Donor cells survived, migrated, and matured into functional GABAergic interneurons, forming synaptic connections.
Shinya Yokomizo, Megi Maci, April M. Stafford, Morgan R. Miller, Stephen J. Perle, Shuzo Inagaki, Shusaku Takahashi, Heather Brown‐Harding, Linda Liang, Alex Lovely, Moustafa Algamal, Rebecca L. Gillani, Theodore J. Zwang, Douglas Richardson, Janice R. Naegele, Daniel Vogt, Ksenia V. Kastanenka   +16 more
wiley   +1 more source

Eyeblink Classical Conditioning in Alcoholism and Fetal Alcohol Spectrum Disorders

Frontiers in Psychiatry, 2015
Alcoholism is a debilitating disorder that can take a significant toll on health and professional and personal relationships. Excessive alcohol consumption can have a serious impact on both drinkers and developing fetuses, leading to long-term learning ...
Dominic T. Cheng, Sandra W Jacobson, Sandra W Jacobson, Joseph L. Jacobson, Joseph L. Jacobson, Christopher D. Molteno, Mark E. Stanton, John E. Desmond   +7 more
doaj   +1 more source

Murine Models for the Study of Fetal Alcohol Spectrum Disorders: An Overview

Frontiers in Pediatrics, 2020
Prenatal alcohol exposure is associated to different physical, behavioral, cognitive, and neurological impairments collectively known as fetal alcohol spectrum disorder.
Laura Almeida, Laura Almeida, Laura Almeida, Vicente Andreu-Fernández, Vicente Andreu-Fernández, Vicente Andreu-Fernández, Elisabet Navarro-Tapia, Elisabet Navarro-Tapia, Elisabet Navarro-Tapia, Rosa Aras-López, Rosa Aras-López, Mariona Serra-Delgado, Leopoldo Martínez, Leopoldo Martínez, Leopoldo Martínez, Oscar García-Algar, Oscar García-Algar, Oscar García-Algar, María Dolores Gómez-Roig, María Dolores Gómez-Roig, María Dolores Gómez-Roig   +20 more
doaj   +1 more source

Extracellular Vesicles of Streptococcus anginosus Mediate Gastritis via Epithelial Barrier Disruption and Macrophage‐driven Inflammation

Advanced Science, EarlyView.
Streptococcus anginosus extracellular vesicles (SA‐EVs) accumulate in gastric tissue, disrupt epithelial tight junctions, and induce gastritis characterized by neutrophil infiltration and elevated cytokines (TNF‐α, IL‐6, IL‐17A). Proteomics identifies TMPC and FBP62 as key SA‐EVs virulence factors; their genetic deletion attenuates inflammation ...
Ying Gong, Lina Duan, Jie Xiao, Yulu Deng, Hongxia Wang, Yajie Zhang, Xiumei Hu, Haifang Wang, Taixue An, Xin Li, Yurong Qiu, Lei Zheng, Haixia Li   +12 more
wiley   +1 more source

ROLE OF SHORT-TERM INTERVENTION IN THE PREVENTION OF FETAL ALCOHOL SYNDROME AND FETAL ALCOHOL SPECTRUM DISORDERS

Acta Biomedica Scientifica, 2014
The review of scientific literature describes modern understanding of the problem of teratogenic effect of alcohol on the fetus and pregnancy outcome.
A. Y. Maryanyan
doaj